Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ACKR4 (atypical chemokine receptor 4)

Identity

Alias_namesCCRL1
chemokine (C-C motif) receptor-like 1
Alias_symbol (synonym)CCR11
CCBP2
VSHK1
CCX-CKR
PPR1
Other aliasCC-CKR-11
CCR-11
CCR10
CCX CKR
CKR-11
HGNC (Hugo) ACKR4
LocusID (NCBI) 51554
Atlas_Id 51003
Location 3q22.1  [Link to chromosome band 3q22]
Location_base_pair Starts at 132597237 and ends at 132602641 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACKR4   1611
Cards
Entrez_Gene (NCBI)ACKR4  51554  atypical chemokine receptor 4
AliasesCC-CKR-11; CCBP2; CCR-11; CCR10; 
CCR11; CCRL1; CCX; CCX-CKR; CKR-11; PPR1; VSHK1
GeneCards (Weizmann)ACKR4
Ensembl hg19 (Hinxton)ENSG00000129048 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129048 [Gene_View]  chr3:132597237-132602641 [Contig_View]  ACKR4 [Vega]
ICGC DataPortalENSG00000129048
TCGA cBioPortalACKR4
AceView (NCBI)ACKR4
Genatlas (Paris)ACKR4
WikiGenes51554
SOURCE (Princeton)ACKR4
Genetics Home Reference (NIH)ACKR4
Genomic and cartography
GoldenPath hg38 (UCSC)ACKR4  -     chr3:132597237-132602641 +  3q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACKR4  -     3q22.1   [Description]    (hg19-Feb_2009)
EnsemblACKR4 - 3q22.1 [CytoView hg19]  ACKR4 - 3q22.1 [CytoView hg38]
Mapping of homologs : NCBIACKR4 [Mapview hg19]  ACKR4 [Mapview hg38]
OMIM606065   
Gene and transcription
Genbank (Entrez)AF110640 AK225927 AK304461 AK313923 BC069438
RefSeq transcript (Entrez)NM_016557 NM_178445
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACKR4
Cluster EST : UnigeneHs.743547 [ NCBI ]
CGAP (NCI)Hs.743547
Alternative Splicing GalleryENSG00000129048
Gene ExpressionACKR4 [ NCBI-GEO ]   ACKR4 [ EBI - ARRAY_EXPRESS ]   ACKR4 [ SEEK ]   ACKR4 [ MEM ]
Gene Expression Viewer (FireBrowse)ACKR4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51554
GTEX Portal (Tissue expression)ACKR4
Human Protein AtlasENSG00000129048-ACKR4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPB9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPB9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPB9
Splice isoforms : SwissVarQ9NPB9
PhosPhoSitePlusQ9NPB9
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)ACKR4    Chemokine_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)ACKR4
DMDM Disease mutations51554
Blocks (Seattle)ACKR4
SuperfamilyQ9NPB9
Human Protein Atlas [tissue]ENSG00000129048-ACKR4 [tissue]
Peptide AtlasQ9NPB9
HPRD07298
IPIIPI00014785   IPI00911115   IPI00883755   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPB9
IntAct (EBI)Q9NPB9
FunCoupENSG00000129048
BioGRIDACKR4
STRING (EMBL)ACKR4
ZODIACACKR4
Ontologies - Pathways
QuickGOQ9NPB9
Ontology : AmiGOchemokine receptor activity  scavenger receptor activity  protein binding  early endosome  plasma membrane  integral component of plasma membrane  receptor-mediated endocytosis  chemotaxis  immune response  G-protein coupled receptor signaling pathway  chemokine binding  recycling endosome  chemokine-mediated signaling pathway  
Ontology : EGO-EBIchemokine receptor activity  scavenger receptor activity  protein binding  early endosome  plasma membrane  integral component of plasma membrane  receptor-mediated endocytosis  chemotaxis  immune response  G-protein coupled receptor signaling pathway  chemokine binding  recycling endosome  chemokine-mediated signaling pathway  
NDEx NetworkACKR4
Atlas of Cancer Signalling NetworkACKR4
Wikipedia pathwaysACKR4
Orthology - Evolution
OrthoDB51554
GeneTree (enSembl)ENSG00000129048
Phylogenetic Trees/Animal Genes : TreeFamACKR4
HOVERGENQ9NPB9
HOGENOMQ9NPB9
Homologs : HomoloGeneACKR4
Homology/Alignments : Family Browser (UCSC)ACKR4
Gene fusions - Rearrangements
Tumor Fusion PortalACKR4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACKR4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACKR4
dbVarACKR4
ClinVarACKR4
1000_GenomesACKR4 
Exome Variant ServerACKR4
ExAC (Exome Aggregation Consortium)ENSG00000129048
GNOMAD BrowserENSG00000129048
Genetic variants : HAPMAP51554
Genomic Variants (DGV)ACKR4 [DGVbeta]
DECIPHERACKR4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACKR4 
Mutations
ICGC Data PortalACKR4 
TCGA Data PortalACKR4 
Broad Tumor PortalACKR4
OASIS PortalACKR4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDACKR4
BioMutasearch ACKR4
DgiDB (Drug Gene Interaction Database)ACKR4
DoCM (Curated mutations)ACKR4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACKR4 (select a term)
intoGenACKR4
Cancer3DACKR4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606065   
Orphanet
DisGeNETACKR4
MedgenACKR4
Genetic Testing Registry ACKR4
NextProtQ9NPB9 [Medical]
TSGene51554
GENETestsACKR4
Target ValidationACKR4
Huge Navigator ACKR4 [HugePedia]
snp3D : Map Gene to Disease51554
BioCentury BCIQACKR4
ClinGenACKR4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51554
Chemical/Pharm GKB GenePA35036
Clinical trialACKR4
Miscellaneous
canSAR (ICR)ACKR4 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACKR4
EVEXACKR4
GoPubMedACKR4
iHOPACKR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:01:49 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.