Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ACOT4 (acyl-CoA thioesterase 4)

Identity

Alias_symbol (synonym)FLJ31235
PTE-Ib
PTE2B
Other aliasPTE1B
HGNC (Hugo) ACOT4
LocusID (NCBI) 122970
Atlas_Id 60091
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 74058410 and ends at 74062470 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
COQ6 (14q24.3) / ACOT4 (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACOT4   19748
Cards
Entrez_Gene (NCBI)ACOT4  122970  acyl-CoA thioesterase 4
AliasesPTE-Ib; PTE1B; PTE2B
GeneCards (Weizmann)ACOT4
Ensembl hg19 (Hinxton) [Gene_View]  chr14:74058410-74062470 [Contig_View]  ACOT4 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr14:74058410-74062470 [Contig_View]  ACOT4 [Vega]
TCGA cBioPortalACOT4
AceView (NCBI)ACOT4
Genatlas (Paris)ACOT4
WikiGenes122970
SOURCE (Princeton)ACOT4
Genetics Home Reference (NIH)ACOT4
Genomic and cartography
GoldenPath hg19 (UCSC)ACOT4  -     chr14:74058410-74062470 +  14q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACOT4  -     14q24.3   [Description]    (hg38-Dec_2013)
EnsemblACOT4 - 14q24.3 [CytoView hg19]  ACOT4 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBIACOT4 [Mapview hg19]  ACOT4 [Mapview hg38]
OMIM614314   
Gene and transcription
Genbank (Entrez)AK055797 AK094223 BC031799 BC090945 BC117341
RefSeq transcript (Entrez)NM_152331
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)ACOT4
Cluster EST : UnigeneHs.49433 [ NCBI ]
CGAP (NCI)Hs.49433
Gene ExpressionACOT4 [ NCBI-GEO ]   ACOT4 [ EBI - ARRAY_EXPRESS ]   ACOT4 [ SEEK ]   ACOT4 [ MEM ]
Gene Expression Viewer (FireBrowse)ACOT4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)122970
GTEX Portal (Tissue expression)ACOT4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N9L9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N9L9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N9L9
Splice isoforms : SwissVarQ8N9L9
Catalytic activity : Enzyme3.1.2.2 [ Enzyme-Expasy ]   3.1.2.23.1.2.2 [ IntEnz-EBI ]   3.1.2.2 [ BRENDA ]   3.1.2.2 [ KEGG ]   
PhosPhoSitePlusQ8N9L9
Domains : Interpro (EBI)AB_hydrolase    Acyl-CoA_thioEstase_long-chain    BAAT_C    Thio_Ohase/aa_AcTrfase   
Domain families : Pfam (Sanger)BAAT_C (PF08840)    Bile_Hydr_Trans (PF04775)   
Domain families : Pfam (NCBI)pfam08840    pfam04775   
Conserved Domain (NCBI)ACOT4
DMDM Disease mutations122970
Blocks (Seattle)ACOT4
PDB (SRS)3K2I   
PDB (PDBSum)3K2I   
PDB (IMB)3K2I   
PDB (RSDB)3K2I   
Structural Biology KnowledgeBase3K2I   
SCOP (Structural Classification of Proteins)3K2I   
CATH (Classification of proteins structures)3K2I   
SuperfamilyQ8N9L9
Peptide AtlasQ8N9L9
HPRD17928
IPIIPI00171211   
Protein Interaction databases
DIP (DOE-UCLA)Q8N9L9
IntAct (EBI)Q8N9L9
BioGRIDACOT4
STRING (EMBL)ACOT4
ZODIACACOT4
Ontologies - Pathways
QuickGOQ8N9L9
Ontology : AmiGOvery long-chain fatty acid metabolic process  long-chain fatty acid metabolic process  succinyl-CoA hydrolase activity  receptor binding  peroxisome  succinyl-CoA metabolic process  acyl-CoA metabolic process  palmitoyl-CoA hydrolase activity  butyrate metabolic process  saturated monocarboxylic acid metabolic process  unsaturated monocarboxylic acid metabolic process  dicarboxylic acid metabolic process  dicarboxylic acid catabolic process  short-chain fatty acid metabolic process  acyl-CoA hydrolase activity  carboxylic ester hydrolase activity  
Ontology : EGO-EBIvery long-chain fatty acid metabolic process  long-chain fatty acid metabolic process  succinyl-CoA hydrolase activity  receptor binding  peroxisome  succinyl-CoA metabolic process  acyl-CoA metabolic process  palmitoyl-CoA hydrolase activity  butyrate metabolic process  saturated monocarboxylic acid metabolic process  unsaturated monocarboxylic acid metabolic process  dicarboxylic acid metabolic process  dicarboxylic acid catabolic process  short-chain fatty acid metabolic process  acyl-CoA hydrolase activity  carboxylic ester hydrolase activity  
Pathways : KEGGFatty acid elongation    Biosynthesis of unsaturated fatty acids   
NDEx NetworkACOT4
Atlas of Cancer Signalling NetworkACOT4
Wikipedia pathwaysACOT4
Orthology - Evolution
OrthoDB122970
Phylogenetic Trees/Animal Genes : TreeFamACOT4
HOVERGENQ8N9L9
HOGENOMQ8N9L9
Homologs : HomoloGeneACOT4
Homology/Alignments : Family Browser (UCSC)ACOT4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACOT4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACOT4
dbVarACOT4
ClinVarACOT4
1000_GenomesACOT4 
Exome Variant ServerACOT4
ExAC (Exome Aggregation Consortium)ACOT4 (select the gene name)
Genetic variants : HAPMAP122970
Genomic Variants (DGV)ACOT4 [DGVbeta]
DECIPHER (Syndromes)14:74058410-74062470  
CONAN: Copy Number AnalysisACOT4 
Mutations
ICGC Data PortalACOT4 
TCGA Data PortalACOT4 
Broad Tumor PortalACOT4
OASIS PortalACOT4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACOT4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACOT4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACOT4
DgiDB (Drug Gene Interaction Database)ACOT4
DoCM (Curated mutations)ACOT4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACOT4 (select a term)
intoGenACOT4
Cancer3DACOT4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614314   
Orphanet
MedgenACOT4
Genetic Testing Registry ACOT4
NextProtQ8N9L9 [Medical]
TSGene122970
GENETestsACOT4
Huge Navigator ACOT4 [HugePedia]
snp3D : Map Gene to Disease122970
BioCentury BCIQACOT4
ClinGenACOT4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD122970
Chemical/Pharm GKB GenePA142672654
Clinical trialACOT4
Miscellaneous
canSAR (ICR)ACOT4 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACOT4
EVEXACOT4
GoPubMedACOT4
iHOPACOT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 11:53:30 CET 2017

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