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ACOT7 (acyl-CoA thioesterase 7)

Identity

Alias_symbol (synonym)BACH
ACH1
ACT
CTE-II
LACH1
MGC1126
hBACH
Other aliasLACH
HGNC (Hugo) ACOT7
LocusID (NCBI) 11332
Atlas_Id 740
Location 1p36.31  [Link to chromosome band 1p36]
Location_base_pair Starts at 6264272 and ends at 6393766 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACOT7 (1p36.31) / ACOT7 (1p36.31)ACOT7 (1p36.31) / FUCA1 (1p36.11)ACOT7 (1p36.31) / KLHL21 (1p36.31)
ACOT7 (1p36.31) / NPHP4 (1p36.31)ACOT7 (1p36.31) / NSMCE2 (8q24.13)ACOT7 (1p36.31) / TTC34 (1p36.32)
ACOT7 (1p36.31) / ZCCHC24 (10q22.3)NOL9 (1p36.31) / ACOT7 (1p36.31)NPHP4 (1p36.31) / ACOT7 (1p36.31)
RBM28 (7q32.1) / ACOT7 (1p36.31)ACOT7 1p36.31 / FUCA1 1p36.11ACOT7 1p36.31 / KLHL21 1p36.31
ACOT7 1p36.31 / NSMCE2 8q24.13ACOT7 1p36.31 / TTC34 1p36.32NPHP4 1p36.31 / ACOT7 1p36.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACOT7   24157
Cards
Entrez_Gene (NCBI)ACOT7  11332  acyl-CoA thioesterase 7
AliasesACH1; ACT; BACH; CTE-II; 
LACH; LACH1; hBACH
GeneCards (Weizmann)ACOT7
Ensembl hg19 (Hinxton)ENSG00000097021 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000097021 [Gene_View]  chr1:6264272-6393766 [Contig_View]  ACOT7 [Vega]
ICGC DataPortalENSG00000097021
TCGA cBioPortalACOT7
AceView (NCBI)ACOT7
Genatlas (Paris)ACOT7
WikiGenes11332
SOURCE (Princeton)ACOT7
Genetics Home Reference (NIH)ACOT7
Genomic and cartography
GoldenPath hg38 (UCSC)ACOT7  -     chr1:6264272-6393766 -  1p36.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACOT7  -     1p36.31   [Description]    (hg19-Feb_2009)
EnsemblACOT7 - 1p36.31 [CytoView hg19]  ACOT7 - 1p36.31 [CytoView hg38]
Mapping of homologs : NCBIACOT7 [Mapview hg19]  ACOT7 [Mapview hg38]
OMIM602587   
Gene and transcription
Genbank (Entrez)AB074415 AB074416 AB074417 AB074418 AB074419
RefSeq transcript (Entrez)NM_007274 NM_181862 NM_181863 NM_181864 NM_181865 NM_181866
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACOT7
Cluster EST : UnigeneHs.126137 [ NCBI ]
CGAP (NCI)Hs.126137
Alternative Splicing GalleryENSG00000097021
Gene ExpressionACOT7 [ NCBI-GEO ]   ACOT7 [ EBI - ARRAY_EXPRESS ]   ACOT7 [ SEEK ]   ACOT7 [ MEM ]
Gene Expression Viewer (FireBrowse)ACOT7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11332
GTEX Portal (Tissue expression)ACOT7
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00154   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00154  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00154
Splice isoforms : SwissVarO00154
Catalytic activity : Enzyme3.1.2.2 [ Enzyme-Expasy ]   3.1.2.23.1.2.2 [ IntEnz-EBI ]   3.1.2.2 [ BRENDA ]   3.1.2.2 [ KEGG ]   
PhosPhoSitePlusO00154
Domaine pattern : Prosite (Expaxy)HOTDOG_ACOT (PS51770)   
Domains : Interpro (EBI)HOTDOG_ACOT    HotDog_dom    Thioestr_dom   
Domain families : Pfam (Sanger)4HBT (PF03061)   
Domain families : Pfam (NCBI)pfam03061   
Conserved Domain (NCBI)ACOT7
DMDM Disease mutations11332
Blocks (Seattle)ACOT7
PDB (SRS)2QQ2   
PDB (PDBSum)2QQ2   
PDB (IMB)2QQ2   
PDB (RSDB)2QQ2   
Structural Biology KnowledgeBase2QQ2   
SCOP (Structural Classification of Proteins)2QQ2   
CATH (Classification of proteins structures)2QQ2   
SuperfamilyO00154
Human Protein AtlasENSG00000097021
Peptide AtlasO00154
HPRD12517
IPIIPI00010415   IPI00883762   IPI00746126   IPI00219451   IPI00219452   IPI01011431   IPI01010982   IPI00395748   
Protein Interaction databases
DIP (DOE-UCLA)O00154
IntAct (EBI)O00154
FunCoupENSG00000097021
BioGRIDACOT7
STRING (EMBL)ACOT7
ZODIACACOT7
Ontologies - Pathways
QuickGOO00154
Ontology : AmiGOfatty-acyl-CoA binding  protein binding  nucleoplasm  mitochondrion  cytosol  cytosol  coenzyme A biosynthetic process  palmitoyl-CoA hydrolase activity  long-chain fatty-acyl-CoA biosynthetic process  long-chain fatty acyl-CoA binding  medium-chain fatty-acyl-CoA catabolic process  long-chain fatty-acyl-CoA catabolic process  protein homodimerization activity  acyl-CoA hydrolase activity  medium-chain fatty acid biosynthetic process  carboxylic ester hydrolase activity  extracellular exosome  myristoyl-CoA hydrolase activity  palmitic acid biosynthetic process  
Ontology : EGO-EBIfatty-acyl-CoA binding  protein binding  nucleoplasm  mitochondrion  cytosol  cytosol  coenzyme A biosynthetic process  palmitoyl-CoA hydrolase activity  long-chain fatty-acyl-CoA biosynthetic process  long-chain fatty acyl-CoA binding  medium-chain fatty-acyl-CoA catabolic process  long-chain fatty-acyl-CoA catabolic process  protein homodimerization activity  acyl-CoA hydrolase activity  medium-chain fatty acid biosynthetic process  carboxylic ester hydrolase activity  extracellular exosome  myristoyl-CoA hydrolase activity  palmitic acid biosynthetic process  
Pathways : KEGGFatty acid elongation    Biosynthesis of unsaturated fatty acids   
NDEx NetworkACOT7
Atlas of Cancer Signalling NetworkACOT7
Wikipedia pathwaysACOT7
Orthology - Evolution
OrthoDB11332
GeneTree (enSembl)ENSG00000097021
Phylogenetic Trees/Animal Genes : TreeFamACOT7
HOVERGENO00154
HOGENOMO00154
Homologs : HomoloGeneACOT7
Homology/Alignments : Family Browser (UCSC)ACOT7
Gene fusions - Rearrangements
Fusion : MitelmanACOT7/FUCA1 [1p36.31/1p36.11]  
Fusion : MitelmanACOT7/KLHL21 [1p36.31/1p36.31]  [t(1;1)(p36;p36)]  
Fusion : MitelmanACOT7/NSMCE2 [1p36.31/8q24.13]  [t(1;8)(p36;q24)]  
Fusion : MitelmanACOT7/TTC34 [1p36.31/1p36.32]  [t(1;1)(p36;p36)]  
Fusion : MitelmanNPHP4/ACOT7 [1p36.31/1p36.31]  [t(1;1)(p36;p36)]  
Fusion: TCGAACOT7 1p36.31 FUCA1 1p36.11 BRCA
Fusion: TCGAACOT7 1p36.31 KLHL21 1p36.31 BRCA
Fusion: TCGAACOT7 1p36.31 NSMCE2 8q24.13 BRCA
Fusion: TCGAACOT7 1p36.31 TTC34 1p36.32 BRCA
Fusion: TCGANPHP4 1p36.31 ACOT7 1p36.31 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACOT7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACOT7
dbVarACOT7
ClinVarACOT7
1000_GenomesACOT7 
Exome Variant ServerACOT7
ExAC (Exome Aggregation Consortium)ACOT7 (select the gene name)
Genetic variants : HAPMAP11332
Genomic Variants (DGV)ACOT7 [DGVbeta]
DECIPHERACOT7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACOT7 
Mutations
ICGC Data PortalACOT7 
TCGA Data PortalACOT7 
Broad Tumor PortalACOT7
OASIS PortalACOT7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACOT7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACOT7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACOT7
DgiDB (Drug Gene Interaction Database)ACOT7
DoCM (Curated mutations)ACOT7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACOT7 (select a term)
intoGenACOT7
Cancer3DACOT7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602587   
Orphanet
MedgenACOT7
Genetic Testing Registry ACOT7
NextProtO00154 [Medical]
TSGene11332
GENETestsACOT7
Target ValidationACOT7
Huge Navigator ACOT7 [HugePedia]
snp3D : Map Gene to Disease11332
BioCentury BCIQACOT7
ClinGenACOT7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11332
Chemical/Pharm GKB GenePA142672655
Clinical trialACOT7
Miscellaneous
canSAR (ICR)ACOT7 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACOT7
EVEXACOT7
GoPubMedACOT7
iHOPACOT7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:22:31 CEST 2017

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