Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ACOT8 (acyl-CoA thioesterase 8)

Identity

Alias_namesPTE1
peroxisomal acyl-CoA thioesterase
peroxisomal acyl-CoA thioesterase 1
Alias_symbol (synonym)hACTE-III
hTE
PTE-2
NAP1
Other aliasHNAACTE
PTE-1
PTE2
HGNC (Hugo) ACOT8
LocusID (NCBI) 10005
Atlas_Id 46420
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 45841721 and ends at 45857409 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACOT8   15919
Cards
Entrez_Gene (NCBI)ACOT8  10005  acyl-CoA thioesterase 8
AliasesHNAACTE; NAP1; PTE-1; PTE-2; 
PTE1; PTE2; hACTE-III; hTE
GeneCards (Weizmann)ACOT8
Ensembl hg19 (Hinxton)ENSG00000101473 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101473 [Gene_View]  chr20:45841721-45857409 [Contig_View]  ACOT8 [Vega]
ICGC DataPortalENSG00000101473
TCGA cBioPortalACOT8
AceView (NCBI)ACOT8
Genatlas (Paris)ACOT8
WikiGenes10005
SOURCE (Princeton)ACOT8
Genetics Home Reference (NIH)ACOT8
Genomic and cartography
GoldenPath hg38 (UCSC)ACOT8  -     chr20:45841721-45857409 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACOT8  -     20q13.12   [Description]    (hg19-Feb_2009)
EnsemblACOT8 - 20q13.12 [CytoView hg19]  ACOT8 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIACOT8 [Mapview hg19]  ACOT8 [Mapview hg38]
OMIM608123   
Gene and transcription
Genbank (Entrez)AF014404 AF124264 AK056668 AK126206 AK292494
RefSeq transcript (Entrez)NM_005469 NM_183385 NM_183386
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACOT8
Cluster EST : UnigeneHs.444776 [ NCBI ]
CGAP (NCI)Hs.444776
Alternative Splicing GalleryENSG00000101473
Gene ExpressionACOT8 [ NCBI-GEO ]   ACOT8 [ EBI - ARRAY_EXPRESS ]   ACOT8 [ SEEK ]   ACOT8 [ MEM ]
Gene Expression Viewer (FireBrowse)ACOT8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10005
GTEX Portal (Tissue expression)ACOT8
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14734   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14734  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14734
Splice isoforms : SwissVarO14734
PhosPhoSitePlusO14734
Domains : Interpro (EBI)Acyl_CoA_thio    HotDog_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)ACOT8
DMDM Disease mutations10005
Blocks (Seattle)ACOT8
SuperfamilyO14734
Human Protein AtlasENSG00000101473
Peptide AtlasO14734
HPRD06998
IPIIPI00298202   IPI00373836   IPI00908749   IPI00871999   IPI00643265   IPI00983409   IPI00909572   IPI00977149   IPI01012063   
Protein Interaction databases
DIP (DOE-UCLA)O14734
IntAct (EBI)O14734
FunCoupENSG00000101473
BioGRIDACOT8
STRING (EMBL)ACOT8
ZODIACACOT8
Ontologies - Pathways
QuickGOO14734
Ontology : AmiGOacetyl-CoA hydrolase activity  receptor binding  protein binding  mitochondrion  peroxisomal matrix  peroxisomal matrix  peroxisomal matrix  acyl-CoA metabolic process  bile acid biosynthetic process  fatty acid catabolic process  viral process  CoA hydrolase activity  palmitoyl-CoA hydrolase activity  peroxisome fission  fatty acid beta-oxidation using acyl-CoA oxidase  choloyl-CoA hydrolase activity  long-chain fatty-acyl-CoA biosynthetic process  alpha-linolenic acid metabolic process  dicarboxylic acid catabolic process  negative regulation of CD4 biosynthetic process  acyl-CoA hydrolase activity  acyl-CoA hydrolase activity  carboxylic ester hydrolase activity  medium-chain acyl-CoA hydrolase activity  long-chain acyl-CoA hydrolase activity  
Ontology : EGO-EBIacetyl-CoA hydrolase activity  receptor binding  protein binding  mitochondrion  peroxisomal matrix  peroxisomal matrix  peroxisomal matrix  acyl-CoA metabolic process  bile acid biosynthetic process  fatty acid catabolic process  viral process  CoA hydrolase activity  palmitoyl-CoA hydrolase activity  peroxisome fission  fatty acid beta-oxidation using acyl-CoA oxidase  choloyl-CoA hydrolase activity  long-chain fatty-acyl-CoA biosynthetic process  alpha-linolenic acid metabolic process  dicarboxylic acid catabolic process  negative regulation of CD4 biosynthetic process  acyl-CoA hydrolase activity  acyl-CoA hydrolase activity  carboxylic ester hydrolase activity  medium-chain acyl-CoA hydrolase activity  long-chain acyl-CoA hydrolase activity  
Pathways : KEGGPrimary bile acid biosynthesis    Peroxisome   
NDEx NetworkACOT8
Atlas of Cancer Signalling NetworkACOT8
Wikipedia pathwaysACOT8
Orthology - Evolution
OrthoDB10005
GeneTree (enSembl)ENSG00000101473
Phylogenetic Trees/Animal Genes : TreeFamACOT8
HOVERGENO14734
HOGENOMO14734
Homologs : HomoloGeneACOT8
Homology/Alignments : Family Browser (UCSC)ACOT8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACOT8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACOT8
dbVarACOT8
ClinVarACOT8
1000_GenomesACOT8 
Exome Variant ServerACOT8
ExAC (Exome Aggregation Consortium)ACOT8 (select the gene name)
Genetic variants : HAPMAP10005
Genomic Variants (DGV)ACOT8 [DGVbeta]
DECIPHERACOT8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACOT8 
Mutations
ICGC Data PortalACOT8 
TCGA Data PortalACOT8 
Broad Tumor PortalACOT8
OASIS PortalACOT8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACOT8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACOT8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACOT8
DgiDB (Drug Gene Interaction Database)ACOT8
DoCM (Curated mutations)ACOT8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACOT8 (select a term)
intoGenACOT8
Cancer3DACOT8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608123   
Orphanet
MedgenACOT8
Genetic Testing Registry ACOT8
NextProtO14734 [Medical]
TSGene10005
GENETestsACOT8
Target ValidationACOT8
Huge Navigator ACOT8 [HugePedia]
snp3D : Map Gene to Disease10005
BioCentury BCIQACOT8
ClinGenACOT8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10005
Chemical/Pharm GKB GenePA33941
Clinical trialACOT8
Miscellaneous
canSAR (ICR)ACOT8 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACOT8
EVEXACOT8
GoPubMedACOT8
iHOPACOT8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:45:59 CEST 2017

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