Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ACOX2 (acyl-CoA oxidase 2)

Identity

Alias_namesacyl-Coenzyme A oxidase 2, branched chain
acyl-CoA oxidase 2, branched chain
Alias_symbol (synonym)BRCACOX
BRCOX
THCCox
Other aliasBCOX
CBAS6
HGNC (Hugo) ACOX2
LocusID (NCBI) 8309
Atlas_Id 55740
Location 3p14.3  [Link to chromosome band 3p14]
Location_base_pair Starts at 58505136 and ends at 58537202 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACOX2   120
Cards
Entrez_Gene (NCBI)ACOX2  8309  acyl-CoA oxidase 2
AliasesBCOX; BRCACOX; BRCOX; CBAS6; 
THCCox
GeneCards (Weizmann)ACOX2
Ensembl hg19 (Hinxton)ENSG00000168306 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168306 [Gene_View]  chr3:58505136-58537202 [Contig_View]  ACOX2 [Vega]
ICGC DataPortalENSG00000168306
TCGA cBioPortalACOX2
AceView (NCBI)ACOX2
Genatlas (Paris)ACOX2
WikiGenes8309
SOURCE (Princeton)ACOX2
Genetics Home Reference (NIH)ACOX2
Genomic and cartography
GoldenPath hg38 (UCSC)ACOX2  -     chr3:58505136-58537202 -  3p14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACOX2  -     3p14.3   [Description]    (hg19-Feb_2009)
EnsemblACOX2 - 3p14.3 [CytoView hg19]  ACOX2 - 3p14.3 [CytoView hg38]
Mapping of homologs : NCBIACOX2 [Mapview hg19]  ACOX2 [Mapview hg38]
OMIM601641   617308   
Gene and transcription
Genbank (Entrez)AK298402 AK313512 BC033517 BC047700 BG698950
RefSeq transcript (Entrez)NM_003500
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACOX2
Cluster EST : UnigeneHs.444959 [ NCBI ]
CGAP (NCI)Hs.444959
Alternative Splicing GalleryENSG00000168306
Gene ExpressionACOX2 [ NCBI-GEO ]   ACOX2 [ EBI - ARRAY_EXPRESS ]   ACOX2 [ SEEK ]   ACOX2 [ MEM ]
Gene Expression Viewer (FireBrowse)ACOX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8309
GTEX Portal (Tissue expression)ACOX2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99424   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99424  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99424
Splice isoforms : SwissVarQ99424
Catalytic activity : Enzyme1.17.99.3 [ Enzyme-Expasy ]   1.17.99.31.17.99.3 [ IntEnz-EBI ]   1.17.99.3 [ BRENDA ]   1.17.99.3 [ KEGG ]   
PhosPhoSitePlusQ99424
Domains : Interpro (EBI)Acyl-CoA_ox_N    Acyl-CoA_Oxase/DH_cen-dom    Acyl-CoA_oxidase    Acyl-CoA_oxidase_C    AcylCo_DH/oxidase_C    AcylCoA_DH/ox_N    AcylCoA_DH/oxidase_NM_dom   
Domain families : Pfam (Sanger)ACOX (PF01756)    Acyl-CoA_dh_M (PF02770)    Acyl-CoA_ox_N (PF14749)   
Domain families : Pfam (NCBI)pfam01756    pfam02770    pfam14749   
Conserved Domain (NCBI)ACOX2
DMDM Disease mutations8309
Blocks (Seattle)ACOX2
SuperfamilyQ99424
Human Protein AtlasENSG00000168306
Peptide AtlasQ99424
HPRD09037
IPIIPI00293125   IPI00796345   IPI00797502   IPI00947183   IPI00944913   IPI00946825   
Protein Interaction databases
DIP (DOE-UCLA)Q99424
IntAct (EBI)Q99424
FunCoupENSG00000168306
BioGRIDACOX2
STRING (EMBL)ACOX2
ZODIACACOX2
Ontologies - Pathways
QuickGOQ99424
Ontology : AmiGOacyl-CoA dehydrogenase activity  acyl-CoA oxidase activity  receptor binding  mitochondrion  peroxisome  peroxisome  peroxisomal matrix  bile acid biosynthetic process  positive regulation of cell death  pristanoyl-CoA oxidase activity  fatty acid beta-oxidation using acyl-CoA oxidase  fatty acid beta-oxidation using acyl-CoA oxidase  3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity  protein homodimerization activity  intracellular membrane-bounded organelle  flavin adenine dinucleotide binding  positive regulation of response to oxidative stress  
Ontology : EGO-EBIacyl-CoA dehydrogenase activity  acyl-CoA oxidase activity  receptor binding  mitochondrion  peroxisome  peroxisome  peroxisomal matrix  bile acid biosynthetic process  positive regulation of cell death  pristanoyl-CoA oxidase activity  fatty acid beta-oxidation using acyl-CoA oxidase  fatty acid beta-oxidation using acyl-CoA oxidase  3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity  protein homodimerization activity  intracellular membrane-bounded organelle  flavin adenine dinucleotide binding  positive regulation of response to oxidative stress  
Pathways : KEGGPrimary bile acid biosynthesis    PPAR signaling pathway    Peroxisome   
NDEx NetworkACOX2
Atlas of Cancer Signalling NetworkACOX2
Wikipedia pathwaysACOX2
Orthology - Evolution
OrthoDB8309
GeneTree (enSembl)ENSG00000168306
Phylogenetic Trees/Animal Genes : TreeFamACOX2
HOVERGENQ99424
HOGENOMQ99424
Homologs : HomoloGeneACOX2
Homology/Alignments : Family Browser (UCSC)ACOX2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACOX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACOX2
dbVarACOX2
ClinVarACOX2
1000_GenomesACOX2 
Exome Variant ServerACOX2
ExAC (Exome Aggregation Consortium)ACOX2 (select the gene name)
Genetic variants : HAPMAP8309
Genomic Variants (DGV)ACOX2 [DGVbeta]
DECIPHERACOX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACOX2 
Mutations
ICGC Data PortalACOX2 
TCGA Data PortalACOX2 
Broad Tumor PortalACOX2
OASIS PortalACOX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACOX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACOX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACOX2
DgiDB (Drug Gene Interaction Database)ACOX2
DoCM (Curated mutations)ACOX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACOX2 (select a term)
intoGenACOX2
Cancer3DACOX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601641    617308   
Orphanet
MedgenACOX2
Genetic Testing Registry ACOX2
NextProtQ99424 [Medical]
TSGene8309
GENETestsACOX2
Target ValidationACOX2
Huge Navigator ACOX2 [HugePedia]
snp3D : Map Gene to Disease8309
BioCentury BCIQACOX2
ClinGenACOX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8309
Chemical/Pharm GKB GenePA24444
Clinical trialACOX2
Miscellaneous
canSAR (ICR)ACOX2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACOX2
EVEXACOX2
GoPubMedACOX2
iHOPACOX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:54:14 CEST 2017

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