Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ACOX3 (acyl-CoA oxidase 3, pristanoyl)

Identity

Alias_namesacyl-Coenzyme A oxidase 3
Other alias-
HGNC (Hugo) ACOX3
LocusID (NCBI) 8310
Atlas_Id 43783
Location 4p16.1  [Link to chromosome band 4p16]
Location_base_pair Starts at 8368009 and ends at 8442452 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACOX3 (4p16.1) / ACOX3 (4p16.1)ACOX3 (4p16.1) / C1orf106 (1q32.1)ACOX3 (4p16.1) / DLGAP4 (20q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACOX3   121
Cards
Entrez_Gene (NCBI)ACOX3  8310  acyl-CoA oxidase 3, pristanoyl
Aliases
GeneCards (Weizmann)ACOX3
Ensembl hg19 (Hinxton)ENSG00000087008 [Gene_View]  chr4:8368009-8442452 [Contig_View]  ACOX3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000087008 [Gene_View]  chr4:8368009-8442452 [Contig_View]  ACOX3 [Vega]
ICGC DataPortalENSG00000087008
TCGA cBioPortalACOX3
AceView (NCBI)ACOX3
Genatlas (Paris)ACOX3
WikiGenes8310
SOURCE (Princeton)ACOX3
Genetics Home Reference (NIH)ACOX3
Genomic and cartography
GoldenPath hg19 (UCSC)ACOX3  -     chr4:8368009-8442452 -  4p16.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACOX3  -     4p16.1   [Description]    (hg38-Dec_2013)
EnsemblACOX3 - 4p16.1 [CytoView hg19]  ACOX3 - 4p16.1 [CytoView hg38]
Mapping of homologs : NCBIACOX3 [Mapview hg19]  ACOX3 [Mapview hg38]
OMIM603402   
Gene and transcription
Genbank (Entrez)AK225080 AK313242 BC017053 CA306669 DA949869
RefSeq transcript (Entrez)NM_001101667 NM_003501
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006051 NW_004929314
Consensus coding sequences : CCDS (NCBI)ACOX3
Cluster EST : UnigeneHs.479122 [ NCBI ]
CGAP (NCI)Hs.479122
Alternative Splicing GalleryENSG00000087008
Gene ExpressionACOX3 [ NCBI-GEO ]   ACOX3 [ EBI - ARRAY_EXPRESS ]   ACOX3 [ SEEK ]   ACOX3 [ MEM ]
Gene Expression Viewer (FireBrowse)ACOX3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8310
GTEX Portal (Tissue expression)ACOX3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15254   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15254  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15254
Splice isoforms : SwissVarO15254
Catalytic activity : Enzyme1.3.3.6 [ Enzyme-Expasy ]   1.3.3.61.3.3.6 [ IntEnz-EBI ]   1.3.3.6 [ BRENDA ]   1.3.3.6 [ KEGG ]   
PhosPhoSitePlusO15254
Domains : Interpro (EBI)Acyl-CoA_Oxase/DH_cen-dom    Acyl-CoA_oxidase    Acyl-CoA_oxidase_C    AcylCo_DH/oxidase_C    AcylCoA_DH/oxidase_NM_dom   
Domain families : Pfam (Sanger)ACOX (PF01756)    Acyl-CoA_dh_1 (PF00441)    Acyl-CoA_dh_M (PF02770)   
Domain families : Pfam (NCBI)pfam01756    pfam00441    pfam02770   
Conserved Domain (NCBI)ACOX3
DMDM Disease mutations8310
Blocks (Seattle)ACOX3
SuperfamilyO15254
Human Protein AtlasENSG00000087008
Peptide AtlasO15254
HPRD04552
IPIIPI00020226   IPI00827610   IPI00966246   
Protein Interaction databases
DIP (DOE-UCLA)O15254
IntAct (EBI)O15254
FunCoupENSG00000087008
BioGRIDACOX3
STRING (EMBL)ACOX3
ZODIACACOX3
Ontologies - Pathways
QuickGOO15254
Ontology : AmiGOfatty-acyl-CoA binding  acyl-CoA dehydrogenase activity  receptor binding  mitochondrion  peroxisome  peroxisomal matrix  electron carrier activity  membrane  pristanoyl-CoA oxidase activity  pristanoyl-CoA oxidase activity  fatty acid beta-oxidation using acyl-CoA dehydrogenase  fatty acid beta-oxidation using acyl-CoA oxidase  fatty acid beta-oxidation using acyl-CoA oxidase  flavin adenine dinucleotide binding  oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor  lipid homeostasis  
Ontology : EGO-EBIfatty-acyl-CoA binding  acyl-CoA dehydrogenase activity  receptor binding  mitochondrion  peroxisome  peroxisomal matrix  electron carrier activity  membrane  pristanoyl-CoA oxidase activity  pristanoyl-CoA oxidase activity  fatty acid beta-oxidation using acyl-CoA dehydrogenase  fatty acid beta-oxidation using acyl-CoA oxidase  fatty acid beta-oxidation using acyl-CoA oxidase  flavin adenine dinucleotide binding  oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor  lipid homeostasis  
Pathways : KEGGFatty acid degradation    alpha-Linolenic acid metabolism    Biosynthesis of unsaturated fatty acids    PPAR signaling pathway    Peroxisome   
NDEx NetworkACOX3
Atlas of Cancer Signalling NetworkACOX3
Wikipedia pathwaysACOX3
Orthology - Evolution
OrthoDB8310
GeneTree (enSembl)ENSG00000087008
Phylogenetic Trees/Animal Genes : TreeFamACOX3
HOVERGENO15254
HOGENOMO15254
Homologs : HomoloGeneACOX3
Homology/Alignments : Family Browser (UCSC)ACOX3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACOX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACOX3
dbVarACOX3
ClinVarACOX3
1000_GenomesACOX3 
Exome Variant ServerACOX3
ExAC (Exome Aggregation Consortium)ACOX3 (select the gene name)
Genetic variants : HAPMAP8310
Genomic Variants (DGV)ACOX3 [DGVbeta]
DECIPHER (Syndromes)4:8368009-8442452  ENSG00000087008
CONAN: Copy Number AnalysisACOX3 
Mutations
ICGC Data PortalACOX3 
TCGA Data PortalACOX3 
Broad Tumor PortalACOX3
OASIS PortalACOX3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACOX3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACOX3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ACOX3
DgiDB (Drug Gene Interaction Database)ACOX3
DoCM (Curated mutations)ACOX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACOX3 (select a term)
intoGenACOX3
Cancer3DACOX3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603402   
Orphanet
MedgenACOX3
Genetic Testing Registry ACOX3
NextProtO15254 [Medical]
TSGene8310
GENETestsACOX3
Huge Navigator ACOX3 [HugePedia]
snp3D : Map Gene to Disease8310
BioCentury BCIQACOX3
ClinGenACOX3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8310
Chemical/Pharm GKB GenePA24445
Clinical trialACOX3
Miscellaneous
canSAR (ICR)ACOX3 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACOX3
EVEXACOX3
GoPubMedACOX3
iHOPACOX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:51:23 CEST 2017

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