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ACP2 (acid phosphatase 2, lysosomal)

Identity

Alias_symbol (synonym)LAP
Other alias
HGNC (Hugo) ACP2
LocusID (NCBI) 53
Atlas_Id 554
Location 11p11.2  [Link to chromosome band 11p11]
Location_base_pair Starts at 47239302 and ends at 47248628 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACP2 (11p11.2) / KIRREL3 (11q24.2)ACP2 (11p11.2) / MRVI1-AS1 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACP2   123
Cards
Entrez_Gene (NCBI)ACP2  53  acid phosphatase 2, lysosomal
AliasesLAP
GeneCards (Weizmann)ACP2
Ensembl hg19 (Hinxton)ENSG00000134575 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134575 [Gene_View]  chr11:47239302-47248628 [Contig_View]  ACP2 [Vega]
ICGC DataPortalENSG00000134575
TCGA cBioPortalACP2
AceView (NCBI)ACP2
Genatlas (Paris)ACP2
WikiGenes53
SOURCE (Princeton)ACP2
Genetics Home Reference (NIH)ACP2
Genomic and cartography
GoldenPath hg38 (UCSC)ACP2  -     chr11:47239302-47248628 -  11p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACP2  -     11p11.2   [Description]    (hg19-Feb_2009)
EnsemblACP2 - 11p11.2 [CytoView hg19]  ACP2 - 11p11.2 [CytoView hg38]
Mapping of homologs : NCBIACP2 [Mapview hg19]  ACP2 [Mapview hg38]
OMIM171650   200950   
Gene and transcription
Genbank (Entrez)AK298122 AK298439 AK299382 AK300569 AK300911
RefSeq transcript (Entrez)NM_001131064 NM_001302489 NM_001302490 NM_001302491 NM_001302492 NM_001610
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACP2
Cluster EST : UnigeneHs.532492 [ NCBI ]
CGAP (NCI)Hs.532492
Alternative Splicing GalleryENSG00000134575
Gene ExpressionACP2 [ NCBI-GEO ]   ACP2 [ EBI - ARRAY_EXPRESS ]   ACP2 [ SEEK ]   ACP2 [ MEM ]
Gene Expression Viewer (FireBrowse)ACP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53
GTEX Portal (Tissue expression)ACP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11117   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11117  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11117
Splice isoforms : SwissVarP11117
Catalytic activity : Enzyme3.1.3.2 [ Enzyme-Expasy ]   3.1.3.23.1.3.2 [ IntEnz-EBI ]   3.1.3.2 [ BRENDA ]   3.1.3.2 [ KEGG ]   
PhosPhoSitePlusP11117
Domaine pattern : Prosite (Expaxy)HIS_ACID_PHOSPHAT_1 (PS00616)    HIS_ACID_PHOSPHAT_2 (PS00778)   
Domains : Interpro (EBI)Acid_Pase_AS    His_Pase_clade-2    His_PPase_superfam   
Domain families : Pfam (Sanger)His_Phos_2 (PF00328)   
Domain families : Pfam (NCBI)pfam00328   
Conserved Domain (NCBI)ACP2
DMDM Disease mutations53
Blocks (Seattle)ACP2
SuperfamilyP11117
Human Protein AtlasENSG00000134575
Peptide AtlasP11117
HPRD01375
IPIIPI00003807   IPI01014507   IPI01010611   IPI00977516   IPI00976906   IPI00974018   IPI00975825   IPI01015683   IPI00983335   IPI00909518   IPI00984373   IPI00925377   
Protein Interaction databases
DIP (DOE-UCLA)P11117
IntAct (EBI)P11117
FunCoupENSG00000134575
BioGRIDACP2
STRING (EMBL)ACP2
ZODIACACP2
Ontologies - Pathways
QuickGOP11117
Ontology : AmiGOskeletal system development  acid phosphatase activity  lysosome  lysosomal membrane  lysosome organization  membrane  integral component of membrane  dephosphorylation  lysosomal lumen  extracellular exosome  
Ontology : EGO-EBIskeletal system development  acid phosphatase activity  lysosome  lysosomal membrane  lysosome organization  membrane  integral component of membrane  dephosphorylation  lysosomal lumen  extracellular exosome  
Pathways : KEGGRiboflavin metabolism    Lysosome   
NDEx NetworkACP2
Atlas of Cancer Signalling NetworkACP2
Wikipedia pathwaysACP2
Orthology - Evolution
OrthoDB53
GeneTree (enSembl)ENSG00000134575
Phylogenetic Trees/Animal Genes : TreeFamACP2
HOVERGENP11117
HOGENOMP11117
Homologs : HomoloGeneACP2
Homology/Alignments : Family Browser (UCSC)ACP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACP2
dbVarACP2
ClinVarACP2
1000_GenomesACP2 
Exome Variant ServerACP2
ExAC (Exome Aggregation Consortium)ACP2 (select the gene name)
Genetic variants : HAPMAP53
Genomic Variants (DGV)ACP2 [DGVbeta]
DECIPHERACP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACP2 
Mutations
ICGC Data PortalACP2 
TCGA Data PortalACP2 
Broad Tumor PortalACP2
OASIS PortalACP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACP2
DgiDB (Drug Gene Interaction Database)ACP2
DoCM (Curated mutations)ACP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACP2 (select a term)
intoGenACP2
Cancer3DACP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM171650    200950   
Orphanet
MedgenACP2
Genetic Testing Registry ACP2
NextProtP11117 [Medical]
TSGene53
GENETestsACP2
Target ValidationACP2
Huge Navigator ACP2 [HugePedia]
snp3D : Map Gene to Disease53
BioCentury BCIQACP2
ClinGenACP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53
Chemical/Pharm GKB GenePA24447
Clinical trialACP2
Miscellaneous
canSAR (ICR)ACP2 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACP2
EVEXACP2
GoPubMedACP2
iHOPACP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:46:00 CEST 2017

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