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ACP3 (acid phosphatase 3)

Identity

Alias (NCBI)5'-NT
ACP-3
ACPP
TM-PAP
HGNC (Hugo) ACP3
HGNC Alias symbACP-3
PAP
TM-PAP
HGNC Alias nameprostatic acid phosphatase
HGNC Previous nameACPP
HGNC Previous nameacid phosphatase, prostate
LocusID (NCBI) 55
Atlas_Id 53343
Location 3q22.1  [Link to chromosome band 3q22]
Location_base_pair Starts at 132317407 and ends at 132358841 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PKM2 ACPP 3q22.1RPLP2 11p15.5 / ACPP 3q22.1
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

 

Nomenclature
HGNC (Hugo)ACP3   125
Cards
Entrez_Gene (NCBI)ACP3    acid phosphatase 3
Aliases5'-NT; ACP-3; ACPP; TM-PAP
GeneCards (Weizmann)ACP3
Ensembl hg19 (Hinxton)ENSG00000014257 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000014257 [Gene_View]  ENSG00000014257 [Sequence]  chr3:132317407-132358841 [Contig_View]  ACP3 [Vega]
ICGC DataPortalENSG00000014257
TCGA cBioPortalACP3
AceView (NCBI)ACP3
Genatlas (Paris)ACP3
SOURCE (Princeton)ACP3
Genetics Home Reference (NIH)ACP3
Genomic and cartography
GoldenPath hg38 (UCSC)ACP3  -     chr3:132317407-132358841 +  3q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACP3  -     3q22.1   [Description]    (hg19-Feb_2009)
GoldenPathACP3 - 3q22.1 [CytoView hg19]  ACP3 - 3q22.1 [CytoView hg38]
ImmunoBaseENSG00000014257
Genome Data Viewer NCBIACP3 [Mapview hg19]  
OMIM171790   
Gene and transcription
Genbank (Entrez)AA578274 AB102888 AK300540 AW136372 BC007460
RefSeq transcript (Entrez)NM_001099 NM_001134194 NM_001292037
Consensus coding sequences : CCDS (NCBI)ACP3
Gene ExpressionACP3 [ NCBI-GEO ]   ACP3 [ EBI - ARRAY_EXPRESS ]   ACP3 [ SEEK ]   ACP3 [ MEM ]
Gene Expression Viewer (FireBrowse)ACP3 [ Firebrowse - Broad ]
GenevisibleExpression of ACP3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55
GTEX Portal (Tissue expression)ACP3
Human Protein AtlasENSG00000014257-ACP3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15309   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15309  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15309
PhosPhoSitePlusP15309
Domaine pattern : Prosite (Expaxy)HIS_ACID_PHOSPHAT_1 (PS00616)    HIS_ACID_PHOSPHAT_2 (PS00778)   
Domains : Interpro (EBI)Acid_Pase_AS    His_Pase_clade-2    His_PPase_superfam   
Domain families : Pfam (Sanger)His_Phos_2 (PF00328)   
Domain families : Pfam (NCBI)pfam00328   
Conserved Domain (NCBI)ACP3
PDB (RSDB)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
PDB Europe1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
PDB (PDBSum)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
PDB (IMB)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
Structural Biology KnowledgeBase1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
SCOP (Structural Classification of Proteins)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
CATH (Classification of proteins structures)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
SuperfamilyP15309
AlphaFold pdb e-kbP15309   
Human Protein Atlas [tissue]ENSG00000014257-ACP3 [tissue]
HPRD01378
Protein Interaction databases
DIP (DOE-UCLA)P15309
IntAct (EBI)P15309
BioGRIDACP3
STRING (EMBL)ACP3
ZODIACACP3
Ontologies - Pathways
QuickGOP15309
Ontology : AmiGOacid phosphatase activity  acid phosphatase activity  acid phosphatase activity  protein tyrosine phosphatase activity  protein binding  extracellular space  extracellular space  nucleus  lysosome  lysosomal membrane  cytosol  plasma membrane  plasma membrane  plasma membrane  purine nucleobase metabolic process  thiamine metabolic process  lysosome organization  5'-nucleotidase activity  nucleotide metabolic process  vesicle membrane  integral component of membrane  dephosphorylation  dephosphorylation  phosphatase activity  phosphatase activity  filopodium  peptidyl-tyrosine dephosphorylation  azurophil granule membrane  thiamine phosphate phosphatase activity  identical protein binding  protein homodimerization activity  neutrophil degranulation  adenosine metabolic process  regulation of sensory perception of pain  lysophosphatidic acid phosphatase activity  positive regulation of adenosine receptor signaling pathway  extracellular exosome  
Ontology : EGO-EBIacid phosphatase activity  acid phosphatase activity  acid phosphatase activity  protein tyrosine phosphatase activity  protein binding  extracellular space  extracellular space  nucleus  lysosome  lysosomal membrane  cytosol  plasma membrane  plasma membrane  plasma membrane  purine nucleobase metabolic process  thiamine metabolic process  lysosome organization  5'-nucleotidase activity  nucleotide metabolic process  vesicle membrane  integral component of membrane  dephosphorylation  dephosphorylation  phosphatase activity  phosphatase activity  filopodium  peptidyl-tyrosine dephosphorylation  azurophil granule membrane  thiamine phosphate phosphatase activity  identical protein binding  protein homodimerization activity  neutrophil degranulation  adenosine metabolic process  regulation of sensory perception of pain  lysophosphatidic acid phosphatase activity  positive regulation of adenosine receptor signaling pathway  extracellular exosome  
NDEx NetworkACP3
Atlas of Cancer Signalling NetworkACP3
Wikipedia pathwaysACP3
Orthology - Evolution
OrthoDB55
GeneTree (enSembl)ENSG00000014257
Phylogenetic Trees/Animal Genes : TreeFamACP3
Homologs : HomoloGeneACP3
Homology/Alignments : Family Browser (UCSC)ACP3
Gene fusions - Rearrangements
Fusion : MitelmanPKM/ACPP [15q23/3q22.1]  
Fusion : MitelmanRPLP2/ACPP [11p15.5/3q22.1]  
Fusion : QuiverACP3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACP3
dbVarACP3
ClinVarACP3
MonarchACP3
1000_GenomesACP3 
Exome Variant ServerACP3
GNOMAD BrowserENSG00000014257
Varsome BrowserACP3
ACMGACP3 variants
VarityP15309
Genomic Variants (DGV)ACP3 [DGVbeta]
DECIPHERACP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACP3 
Mutations
ICGC Data PortalACP3 
TCGA Data PortalACP3 
Broad Tumor PortalACP3
OASIS PortalACP3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDACP3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaACP3
DgiDB (Drug Gene Interaction Database)ACP3
DoCM (Curated mutations)ACP3
CIViC (Clinical Interpretations of Variants in Cancer)ACP3
Cancer3DACP3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM171790   
Orphanet
DisGeNETACP3
MedgenACP3
Genetic Testing Registry ACP3
NextProtP15309 [Medical]
GENETestsACP3
Target ValidationACP3
Huge Navigator ACP3 [HugePedia]
ClinGenACP3
Clinical trials, drugs, therapy
MyCancerGenomeACP3
Protein Interactions : CTDACP3
PharosP15309
Clinical trialACP3
Miscellaneous
canSAR (ICR)ACP3
HarmonizomeACP3
DataMed IndexACP3
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXACP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:58:15 CEST 2021

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