Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ACP5 (acid phosphatase 5, tartrate resistant)

Identity

Alias (NCBI)HPAP
TRACP5a
TRACP5b
TRAP
TrATPase
HGNC (Hugo) ACP5
HGNC Alias symbTRAP
HPAP
HGNC Alias nametartrate-resistant acid phosphatase
 human purple acid phosphatase
LocusID (NCBI) 54
Atlas_Id 555
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 11574660 and ends at 11577645 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACP5 (19p13.2) / GTF2F1 (19p13.3)ACP5 (19p13.2) / PSAP (10q22.1)GTF2F1 (19p13.3) / ACP5 (19p13.2)
PSAP (10q22.1) / ACP5 (19p13.2)ACP5 19p13.2 / GTF2F1 19p13.3GTF2F1 19p13.3 / ACP5 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Enchondromatosis

External links

Nomenclature
HGNC (Hugo)ACP5   124
Cards
Entrez_Gene (NCBI)ACP5    acid phosphatase 5, tartrate resistant
AliasesHPAP; TRACP5a; TRACP5b; TRAP; 
TrATPase
GeneCards (Weizmann)ACP5
Ensembl hg19 (Hinxton)ENSG00000102575 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102575 [Gene_View]  ENSG00000102575 [Sequence]  chr19:11574660-11577645 [Contig_View]  ACP5 [Vega]
ICGC DataPortalENSG00000102575
TCGA cBioPortalACP5
AceView (NCBI)ACP5
Genatlas (Paris)ACP5
SOURCE (Princeton)ACP5
Genetics Home Reference (NIH)ACP5
Genomic and cartography
GoldenPath hg38 (UCSC)ACP5  -     chr19:11574660-11577645 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACP5  -     19p13.2   [Description]    (hg19-Feb_2009)
GoldenPathACP5 - 19p13.2 [CytoView hg19]  ACP5 - 19p13.2 [CytoView hg38]
ImmunoBaseENSG00000102575
genome Data Viewer NCBIACP5 [Mapview hg19]  
OMIM171640   607944   
Gene and transcription
Genbank (Entrez)AK225912 AK290717 AK307164 BC025414 BC111014
RefSeq transcript (Entrez)NM_001111034 NM_001111035 NM_001111036 NM_001322023 NM_001611
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACP5
Alternative Splicing GalleryENSG00000102575
Gene ExpressionACP5 [ NCBI-GEO ]   ACP5 [ EBI - ARRAY_EXPRESS ]   ACP5 [ SEEK ]   ACP5 [ MEM ]
Gene Expression Viewer (FireBrowse)ACP5 [ Firebrowse - Broad ]
GenevisibleExpression of ACP5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54
GTEX Portal (Tissue expression)ACP5
Human Protein AtlasENSG00000102575-ACP5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13686   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP13686  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13686
Splice isoforms : SwissVarP13686
Catalytic activity : Enzyme3.1.3.2 [ Enzyme-Expasy ]   3.1.3.23.1.3.2 [ IntEnz-EBI ]   3.1.3.2 [ BRENDA ]   3.1.3.2 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP13686
Domains : Interpro (EBI)Acid_PPase    Calcineurin-like_PHP_ApaH    Metallo-depent_PP-like   
Domain families : Pfam (Sanger)Metallophos (PF00149)   
Domain families : Pfam (NCBI)pfam00149   
Conserved Domain (NCBI)ACP5
Blocks (Seattle)ACP5
PDB (RSDB)1WAR    2BQ8   
PDB Europe1WAR    2BQ8   
PDB (PDBSum)1WAR    2BQ8   
PDB (IMB)1WAR    2BQ8   
Structural Biology KnowledgeBase1WAR    2BQ8   
SCOP (Structural Classification of Proteins)1WAR    2BQ8   
CATH (Classification of proteins structures)1WAR    2BQ8   
SuperfamilyP13686
Human Protein Atlas [tissue]ENSG00000102575-ACP5 [tissue]
Peptide AtlasP13686
HPRD01374
IPIIPI00419240   
Protein Interaction databases
DIP (DOE-UCLA)P13686
IntAct (EBI)P13686
BioGRIDACP5
STRING (EMBL)ACP5
ZODIACACP5
Ontologies - Pathways
QuickGOP13686
Ontology : AmiGOossification  acid phosphatase activity  lysosome  cytosol  riboflavin metabolic process  ferrous iron binding  ferrous iron binding  ferric iron binding  ferric iron binding  integral component of membrane  dephosphorylation  bone resorption  
Ontology : EGO-EBIossification  acid phosphatase activity  lysosome  cytosol  riboflavin metabolic process  ferrous iron binding  ferrous iron binding  ferric iron binding  ferric iron binding  integral component of membrane  dephosphorylation  bone resorption  
Pathways : KEGGRiboflavin metabolism    Lysosome    Osteoclast differentiation    Rheumatoid arthritis   
NDEx NetworkACP5
Atlas of Cancer Signalling NetworkACP5
Wikipedia pathwaysACP5
Orthology - Evolution
OrthoDB54
GeneTree (enSembl)ENSG00000102575
Phylogenetic Trees/Animal Genes : TreeFamACP5
HOGENOMP13686
Homologs : HomoloGeneACP5
Homology/Alignments : Family Browser (UCSC)ACP5
Gene fusions - Rearrangements
Fusion : MitelmanACP5/GTF2F1 [19p13.2/19p13.3]  
Fusion : MitelmanGTF2F1/ACP5 [19p13.3/19p13.2]  
Fusion PortalACP5 19p13.2 GTF2F1 19p13.3 SKCM
Fusion PortalGTF2F1 19p13.3 ACP5 19p13.2 SKCM
Fusion : QuiverACP5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACP5 [hg38]
dbVarACP5
ClinVarACP5
MonarchACP5
1000_GenomesACP5 
Exome Variant ServerACP5
GNOMAD BrowserENSG00000102575
Varsome BrowserACP5
Genomic Variants (DGV)ACP5 [DGVbeta]
DECIPHERACP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACP5 
Mutations
ICGC Data PortalACP5 
TCGA Data PortalACP5 
Broad Tumor PortalACP5
OASIS PortalACP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACP5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DACP5
Mutations and Diseases : HGMDACP5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch ACP5
DgiDB (Drug Gene Interaction Database)ACP5
DoCM (Curated mutations)ACP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACP5 (select a term)
intoGenACP5
Cancer3DACP5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM171640    607944   
Orphanet2842   
DisGeNETACP5
MedgenACP5
Genetic Testing Registry ACP5
NextProtP13686 [Medical]
GENETestsACP5
Target ValidationACP5
Huge Navigator ACP5 [HugePedia]
ClinGenACP5
Clinical trials, drugs, therapy
MyCancerGenomeACP5
Protein Interactions : CTD
Pharm GKB GenePA24448
PharosP13686
Clinical trialACP5
Miscellaneous
canSAR (ICR)ACP5 (select the gene name)
HarmonizomeACP5
DataMed IndexACP5
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXACP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:09:44 CET 2021
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.