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ACPP (acid phosphatase, prostate)

Identity

Other names5'-NT
ACP-3
ACP3
HGNC (Hugo) ACPP
LocusID (NCBI) 55
Location 3q22.1
Location_base_pair Starts at 132036211 and ends at 132077690 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ACPP   125
Cards
Entrez_Gene (NCBI)ACPP  55  acid phosphatase, prostate
GeneCards (Weizmann)ACPP
Ensembl hg19 (Hinxton)ENSG00000014257 [Gene_View]  chr3:132036211-132077690 [Contig_View]  ACPP [Vega]
Ensembl hg38 (Hinxton)ENSG00000014257 [Gene_View]  chr3:132036211-132077690 [Contig_View]  ACPP [Vega]
ICGC DataPortalENSG00000014257
cBioPortalACPP
AceView (NCBI)ACPP
Genatlas (Paris)ACPP
WikiGenes55
SOURCE (Princeton)ACPP
Genomic and cartography
GoldenPath hg19 (UCSC)ACPP  -     chr3:132036211-132077690 +  3q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACPP  -     3q22.1   [Description]    (hg38-Dec_2013)
EnsemblACPP - 3q22.1 [CytoView hg19]  ACPP - 3q22.1 [CytoView hg38]
Mapping of homologs : NCBIACPP [Mapview hg19]  ACPP [Mapview hg38]
OMIM171790   
Gene and transcription
Genbank (Entrez)AA578274 AB102888 AK300540 AW136372 BC007460
RefSeq transcript (Entrez)NM_001099 NM_001134194 NM_001292037
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_005612 NW_001838884 NW_004929311
Consensus coding sequences : CCDS (NCBI)ACPP
Cluster EST : UnigeneHs.433060 [ NCBI ]
CGAP (NCI)Hs.433060
Alternative Splicing : Fast-db (Paris)GSHG0021160
Alternative Splicing GalleryENSG00000014257
Gene ExpressionACPP [ NCBI-GEO ]     ACPP [ SEEK ]   ACPP [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15309 (Uniprot)
NextProtP15309  [Medical]
With graphics : InterProP15309
Splice isoforms : SwissVarP15309 (Swissvar)
Catalytic activity : Enzyme3.1.3.2 [ Enzyme-Expasy ]   3.1.3.23.1.3.2 [ IntEnz-EBI ]   3.1.3.2 [ BRENDA ]   3.1.3.2 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)HIS_ACID_PHOSPHAT_1 (PS00616)    HIS_ACID_PHOSPHAT_2 (PS00778)   
Domains : Interpro (EBI)His_Pase_superF_clade-2    His_PPase_superfam   
Related proteins : CluSTrP15309
Domain families : Pfam (Sanger)His_Phos_2 (PF00328)   
Domain families : Pfam (NCBI)pfam00328   
DMDM Disease mutations55
Blocks (Seattle)P15309
PDB (SRS)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    3PPD   
PDB (PDBSum)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    3PPD   
PDB (IMB)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    3PPD   
PDB (RSDB)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    3PPD   
Human Protein AtlasENSG00000014257
Peptide AtlasP15309
HPRD01378
IPIIPI00396434   IPI00289983   IPI00945650   IPI00946121   IPI00795534   
Protein Interaction databases
DIP (DOE-UCLA)P15309
IntAct (EBI)P15309
FunCoupENSG00000014257
BioGRIDACPP
IntegromeDBACPP
STRING (EMBL)ACPP
Ontologies - Pathways
QuickGOP15309
Ontology : AmiGOacid phosphatase activity  protein binding  extracellular space  extracellular space  intracellular  nucleus  lysosomal membrane  multivesicular body  plasma membrane  purine nucleobase metabolic process  thiamine metabolic process  5'-nucleotidase activity  nucleotide metabolic process  vesicle membrane  integral component of membrane  dephosphorylation  phosphatase activity  secretory granule  filopodium  Golgi cisterna  choline binding  thiamine phosphate phosphatase activity  identical protein binding  protein homodimerization activity  apical part of cell  adenosine metabolic process  regulation of sensory perception of pain  lysophosphatidic acid phosphatase activity  positive regulation of adenosine receptor signaling pathway  extracellular vesicular exosome  
Ontology : EGO-EBIacid phosphatase activity  protein binding  extracellular space  extracellular space  intracellular  nucleus  lysosomal membrane  multivesicular body  plasma membrane  purine nucleobase metabolic process  thiamine metabolic process  5'-nucleotidase activity  nucleotide metabolic process  vesicle membrane  integral component of membrane  dephosphorylation  phosphatase activity  secretory granule  filopodium  Golgi cisterna  choline binding  thiamine phosphate phosphatase activity  identical protein binding  protein homodimerization activity  apical part of cell  adenosine metabolic process  regulation of sensory perception of pain  lysophosphatidic acid phosphatase activity  positive regulation of adenosine receptor signaling pathway  extracellular vesicular exosome  
Pathways : KEGGRiboflavin metabolism   
Protein Interaction DatabaseACPP
DoCM (Curated mutations)ACPP
Wikipedia pathwaysACPP
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerACPP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACPP
dbVarACPP
ClinVarACPP
1000_GenomesACPP 
Exome Variant ServerACPP
SNP (GeneSNP Utah)ACPP
SNP : HGBaseACPP
Genetic variants : HAPMAPACPP
Genomic VariantsACPP  ACPP [DGVbeta]
Mutations
ICGC Data PortalENSG00000014257 
Somatic Mutations in Cancer : COSMICACPP 
CONAN: Copy Number AnalysisACPP 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:132036211-132077690
Mutations and Diseases : HGMDACPP
OMIM171790   
MedgenACPP
NextProtP15309 [Medical]
GENETestsACPP
Disease Genetic AssociationACPP
Huge Navigator ACPP [HugePedia]  ACPP [HugeCancerGEM]
snp3D : Map Gene to Disease55
DGIdb (Drug Gene Interaction db)ACPP
General knowledge
Homologs : HomoloGeneACPP
Homology/Alignments : Family Browser (UCSC)ACPP
Phylogenetic Trees/Animal Genes : TreeFamACPP
Chemical/Protein Interactions : CTD55
Chemical/Pharm GKB GenePA24449
Clinical trialACPP
Cancer Resource (Charite)ENSG00000014257
Other databases
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
CoreMineACPP
GoPubMedACPP
iHOPACPP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 19:59:47 CET 2014

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