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ACPP (acid phosphatase, prostate)

Identity

Other names5'-NT
ACP-3
ACP3
HGNC (Hugo) ACPP
LocusID (NCBI) 55
Atlas_Id 53343
Location 3q22.1
Location_base_pair Starts at 132036211 and ends at 132077690 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACPP (3q22.1) / PAFAH1B1 (17p13.3)PKM (15q23) / ACPP (3q22.1)RPLP2 (11p15.5) / ACPP (3q22.1)
PKM2 ACPP 3q22.1RPLP2 11p15.5 / ACPP 3q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACPP   125
Cards
Entrez_Gene (NCBI)ACPP  55  acid phosphatase, prostate
Aliases5'-NT; ACP-3; ACP3
GeneCards (Weizmann)ACPP
Ensembl hg19 (Hinxton)ENSG00000014257 [Gene_View]  chr3:132036211-132077690 [Contig_View]  ACPP [Vega]
Ensembl hg38 (Hinxton)ENSG00000014257 [Gene_View]  chr3:132036211-132077690 [Contig_View]  ACPP [Vega]
ICGC DataPortalENSG00000014257
TCGA cBioPortalACPP
AceView (NCBI)ACPP
Genatlas (Paris)ACPP
WikiGenes55
SOURCE (Princeton)ACPP
Genomic and cartography
GoldenPath hg19 (UCSC)ACPP  -     chr3:132036211-132077690 +  3q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACPP  -     3q22.1   [Description]    (hg38-Dec_2013)
EnsemblACPP - 3q22.1 [CytoView hg19]  ACPP - 3q22.1 [CytoView hg38]
Mapping of homologs : NCBIACPP [Mapview hg19]  ACPP [Mapview hg38]
OMIM171790   
Gene and transcription
Genbank (Entrez)AA578274 AB102888 AK300540 AW136372 BC007460
RefSeq transcript (Entrez)NM_001099 NM_001134194 NM_001292037
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)ACPP
Cluster EST : UnigeneHs.433060 [ NCBI ]
CGAP (NCI)Hs.433060
Alternative Splicing GalleryENSG00000014257
Gene ExpressionACPP [ NCBI-GEO ]   ACPP [ EBI - ARRAY_EXPRESS ]   ACPP [ SEEK ]   ACPP [ MEM ]
Gene Expression Viewer (FireBrowse)ACPP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55
GTEX Portal (Tissue expression)ACPP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15309 (Uniprot)
NextProtP15309  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15309
Splice isoforms : SwissVarP15309 (Swissvar)
Catalytic activity : Enzyme3.1.3.2 [ Enzyme-Expasy ]   3.1.3.23.1.3.2 [ IntEnz-EBI ]   3.1.3.2 [ BRENDA ]   3.1.3.2 [ KEGG ]   
PhosPhoSitePlusP15309
Domaine pattern : Prosite (Expaxy)HIS_ACID_PHOSPHAT_1 (PS00616)    HIS_ACID_PHOSPHAT_2 (PS00778)   
Domains : Interpro (EBI)His_Pase_superF_clade-2    His_PPase_superfam   
Domain families : Pfam (Sanger)His_Phos_2 (PF00328)   
Domain families : Pfam (NCBI)pfam00328   
DMDM Disease mutations55
Blocks (Seattle)ACPP
PDB (SRS)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
PDB (PDBSum)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
PDB (IMB)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
PDB (RSDB)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
Structural Biology KnowledgeBase1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
SCOP (Structural Classification of Proteins)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
CATH (Classification of proteins structures)1CVI    1ND5    1ND6    2HPA    2L3H    2L77    2L79    2MG0    3PPD   
SuperfamilyP15309
Human Protein AtlasENSG00000014257
Peptide AtlasP15309
HPRD01378
IPIIPI00396434   IPI00289983   IPI00945650   IPI00946121   IPI00795534   
Protein Interaction databases
DIP (DOE-UCLA)P15309
IntAct (EBI)P15309
FunCoupENSG00000014257
BioGRIDACPP
STRING (EMBL)ACPP
ZODIACACPP
Ontologies - Pathways
QuickGOP15309
Ontology : AmiGOacid phosphatase activity  extracellular space  extracellular space  intracellular  nucleus  lysosomal membrane  multivesicular body  plasma membrane  purine nucleobase metabolic process  thiamine metabolic process  5'-nucleotidase activity  nucleotide metabolic process  vesicle membrane  integral component of membrane  dephosphorylation  phosphatase activity  secretory granule  filopodium  Golgi cisterna  choline binding  thiamine phosphate phosphatase activity  identical protein binding  apical part of cell  adenosine metabolic process  regulation of sensory perception of pain  lysophosphatidic acid phosphatase activity  positive regulation of adenosine receptor signaling pathway  extracellular exosome  
Ontology : EGO-EBIacid phosphatase activity  extracellular space  extracellular space  intracellular  nucleus  lysosomal membrane  multivesicular body  plasma membrane  purine nucleobase metabolic process  thiamine metabolic process  5'-nucleotidase activity  nucleotide metabolic process  vesicle membrane  integral component of membrane  dephosphorylation  phosphatase activity  secretory granule  filopodium  Golgi cisterna  choline binding  thiamine phosphate phosphatase activity  identical protein binding  apical part of cell  adenosine metabolic process  regulation of sensory perception of pain  lysophosphatidic acid phosphatase activity  positive regulation of adenosine receptor signaling pathway  extracellular exosome  
Pathways : KEGGRiboflavin metabolism   
NDEx Network
Atlas of Cancer Signalling NetworkACPP
Wikipedia pathwaysACPP
Orthology - Evolution
OrthoDB55
GeneTree (enSembl)ENSG00000014257
Phylogenetic Trees/Animal Genes : TreeFamACPP
Homologs : HomoloGeneACPP
Homology/Alignments : Family Browser (UCSC)ACPP
Gene fusions - Rearrangements
Fusion: TCGAPKM2 ACPP 3q22.1 PRAD
Fusion: TCGARPLP2 11p15.5 ACPP 3q22.1 PRAD
Polymorphisms : SNP, variants
NCBI Variation ViewerACPP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACPP
dbVarACPP
ClinVarACPP
1000_GenomesACPP 
Exome Variant ServerACPP
ExAC (Exome Aggregation Consortium)ACPP (select the gene name)
Genetic variants : HAPMAP55
Genomic Variants (DGV)ACPP [DGVbeta]
Mutations
ICGC Data PortalACPP 
TCGA Data PortalACPP 
Broad Tumor PortalACPP
OASIS PortalACPP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACPP 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACPP
DgiDB (Drug Gene Interaction Database)ACPP
DoCM (Curated mutations)ACPP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACPP (select a term)
intoGenACPP
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:132036211-132077690  ENSG00000014257
CONAN: Copy Number AnalysisACPP 
Mutations and Diseases : HGMDACPP
OMIM171790   
MedgenACPP
Genetic Testing Registry ACPP
NextProtP15309 [Medical]
TSGene55
GENETestsACPP
Huge Navigator ACPP [HugePedia]
snp3D : Map Gene to Disease55
BioCentury BCIQACPP
ClinGenACPP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55
Chemical/Pharm GKB GenePA24449
Clinical trialACPP
Miscellaneous
canSAR (ICR)ACPP (select the gene name)
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACPP
EVEXACPP
GoPubMedACPP
iHOPACPP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 10:52:42 CEST 2016

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