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ACSS2 (acyl-CoA synthetase short-chain family member 2)

Identity

Alias_namesACAS2
acetyl-Coenzyme A synthetase 2 (ADP forming)
Alias_symbol (synonym)ACS
ACSA
AceCS
dJ1161H23.1
Other aliasACECS
HGNC (Hugo) ACSS2
LocusID (NCBI) 55902
Atlas_Id 46903
Location 20q11.22  [Link to chromosome band 20q11]
Location_base_pair Starts at 34876525 and ends at 34927966 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACSS2 (20q11.22) / AMBRA1 (11p11.2)ACSS2 (20q11.22) / GSS (20q11.22)FRS2 (12q15) / ACSS2 (20q11.22)
GSS (20q11.22) / ACSS2 (20q11.22)ACSS2 20q11.22 / GSS 20q11.22FRS2 12q15 / ACSS2 20q11.22
GSS 20q11.22 / ACSS2 20q11.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACSS2   15814
Cards
Entrez_Gene (NCBI)ACSS2  55902  acyl-CoA synthetase short-chain family member 2
AliasesACAS2; ACECS; ACS; ACSA; 
dJ1161H23.1
GeneCards (Weizmann)ACSS2
Ensembl hg19 (Hinxton)ENSG00000131069 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131069 [Gene_View]  chr20:34876525-34927966 [Contig_View]  ACSS2 [Vega]
ICGC DataPortalENSG00000131069
TCGA cBioPortalACSS2
AceView (NCBI)ACSS2
Genatlas (Paris)ACSS2
WikiGenes55902
SOURCE (Princeton)ACSS2
Genetics Home Reference (NIH)ACSS2
Genomic and cartography
GoldenPath hg38 (UCSC)ACSS2  -     chr20:34876525-34927966 +  20q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACSS2  -     20q11.22   [Description]    (hg19-Feb_2009)
EnsemblACSS2 - 20q11.22 [CytoView hg19]  ACSS2 - 20q11.22 [CytoView hg38]
Mapping of homologs : NCBIACSS2 [Mapview hg19]  ACSS2 [Mapview hg38]
OMIM605832   
Gene and transcription
Genbank (Entrez)AF263614 AI674262 AK000162 AK000188 AK022608
RefSeq transcript (Entrez)NM_001076552 NM_001242393 NM_018677 NM_139274
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACSS2
Cluster EST : UnigeneHs.517034 [ NCBI ]
CGAP (NCI)Hs.517034
Alternative Splicing GalleryENSG00000131069
Gene ExpressionACSS2 [ NCBI-GEO ]   ACSS2 [ EBI - ARRAY_EXPRESS ]   ACSS2 [ SEEK ]   ACSS2 [ MEM ]
Gene Expression Viewer (FireBrowse)ACSS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55902
GTEX Portal (Tissue expression)ACSS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR19   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NR19  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR19
Splice isoforms : SwissVarQ9NR19
Catalytic activity : Enzyme6.2.1.1 [ Enzyme-Expasy ]   6.2.1.16.2.1.1 [ IntEnz-EBI ]   6.2.1.1 [ BRENDA ]   6.2.1.1 [ KEGG ]   
PhosPhoSitePlusQ9NR19
Domaine pattern : Prosite (Expaxy)AMP_BINDING (PS00455)   
Domains : Interpro (EBI)Ac_CoA_lig    ACAS_N    AMP-bd_C    AMP-binding_CS    AMP-dep_Synth/Lig   
Domain families : Pfam (Sanger)ACAS_N (PF16177)    AMP-binding (PF00501)    AMP-binding_C (PF13193)   
Domain families : Pfam (NCBI)pfam16177    pfam00501    pfam13193   
Conserved Domain (NCBI)ACSS2
DMDM Disease mutations55902
Blocks (Seattle)ACSS2
SuperfamilyQ9NR19
Human Protein AtlasENSG00000131069
Peptide AtlasQ9NR19
IPIIPI00413730   IPI00873455   IPI00945466   IPI00909325   IPI00549564   IPI01010854   IPI00946400   IPI00946160   IPI00946018   IPI00945309   IPI00946173   IPI00946252   IPI00945625   IPI00945873   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR19
IntAct (EBI)Q9NR19
FunCoupENSG00000131069
BioGRIDACSS2
STRING (EMBL)ACSS2
ZODIACACSS2
Ontologies - Pathways
QuickGOQ9NR19
Ontology : AmiGOacetate-CoA ligase activity  acetate-CoA ligase activity  ATP binding  nucleoplasm  cytoplasm  cytosol  cytosol  ethanol oxidation  lipid biosynthetic process  AMP binding  acetate biosynthetic process  acetyl-CoA biosynthetic process from acetate  propionate biosynthetic process  intracellular membrane-bounded organelle  
Ontology : EGO-EBIacetate-CoA ligase activity  acetate-CoA ligase activity  ATP binding  nucleoplasm  cytoplasm  cytosol  cytosol  ethanol oxidation  lipid biosynthetic process  AMP binding  acetate biosynthetic process  acetyl-CoA biosynthetic process from acetate  propionate biosynthetic process  intracellular membrane-bounded organelle  
Pathways : BIOCARTAMitochondrial Carnitine Palmitoyltransferase (CPT) System [Genes]   
Pathways : KEGGGlycolysis / Gluconeogenesis    Pyruvate metabolism    Propanoate metabolism   
NDEx NetworkACSS2
Atlas of Cancer Signalling NetworkACSS2
Wikipedia pathwaysACSS2
Orthology - Evolution
OrthoDB55902
GeneTree (enSembl)ENSG00000131069
Phylogenetic Trees/Animal Genes : TreeFamACSS2
HOVERGENQ9NR19
HOGENOMQ9NR19
Homologs : HomoloGeneACSS2
Homology/Alignments : Family Browser (UCSC)ACSS2
Gene fusions - Rearrangements
Fusion : MitelmanACSS2/GSS [20q11.22/20q11.22]  
Fusion : MitelmanFRS2/ACSS2 [12q15/20q11.22]  [t(12;20)(q15;q11)]  
Fusion : MitelmanGSS/ACSS2 [20q11.22/20q11.22]  [t(20;20)(q11;q11)]  
Fusion: TCGAACSS2 20q11.22 GSS 20q11.22 BRCA
Fusion: TCGAFRS2 12q15 ACSS2 20q11.22 LUAD
Fusion: TCGAGSS 20q11.22 ACSS2 20q11.22 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACSS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACSS2
dbVarACSS2
ClinVarACSS2
1000_GenomesACSS2 
Exome Variant ServerACSS2
ExAC (Exome Aggregation Consortium)ACSS2 (select the gene name)
Genetic variants : HAPMAP55902
Genomic Variants (DGV)ACSS2 [DGVbeta]
DECIPHERACSS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACSS2 
Mutations
ICGC Data PortalACSS2 
TCGA Data PortalACSS2 
Broad Tumor PortalACSS2
OASIS PortalACSS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACSS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACSS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACSS2
DgiDB (Drug Gene Interaction Database)ACSS2
DoCM (Curated mutations)ACSS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACSS2 (select a term)
intoGenACSS2
Cancer3DACSS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605832   
Orphanet
MedgenACSS2
Genetic Testing Registry ACSS2
NextProtQ9NR19 [Medical]
TSGene55902
GENETestsACSS2
Target ValidationACSS2
Huge Navigator ACSS2 [HugePedia]
snp3D : Map Gene to Disease55902
BioCentury BCIQACSS2
ClinGenACSS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55902
Chemical/Pharm GKB GenePA24429
Clinical trialACSS2
Miscellaneous
canSAR (ICR)ACSS2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACSS2
EVEXACSS2
GoPubMedACSS2
iHOPACSS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:22:35 CEST 2017

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