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ACTG2 (actin, gamma 2, smooth muscle, enteric)

Identity

Alias_namesACTL3
ACTA3
Alias_symbol (synonym)ACTSG
Other aliasACT
ACTE
VSCM
HGNC (Hugo) ACTG2
LocusID (NCBI) 72
Atlas_Id 55744
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 73892966 and ends at 73919653 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACTG2 (2p13.1) / ACTG2 (2p13.1)ACTG2 (2p13.1) / ERCC2 (19q13.32)BATF2 (11q13.1) / ACTG2 (2p13.1)
DGUOK (2p13.1) / ACTG2 (2p13.1)HOXB13 (17q21.32) / ACTG2 (2p13.1)PELI1 (2p14) / ACTG2 (2p13.1)
TET3 (2p13.1) / ACTG2 (2p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACTG2   145
Cards
Entrez_Gene (NCBI)ACTG2  72  actin, gamma 2, smooth muscle, enteric
AliasesACT; ACTA3; ACTE; ACTL3; 
ACTSG; VSCM
GeneCards (Weizmann)ACTG2
Ensembl hg19 (Hinxton)ENSG00000163017 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163017 [Gene_View]  chr2:73892966-73919653 [Contig_View]  ACTG2 [Vega]
ICGC DataPortalENSG00000163017
TCGA cBioPortalACTG2
AceView (NCBI)ACTG2
Genatlas (Paris)ACTG2
WikiGenes72
SOURCE (Princeton)ACTG2
Genetics Home Reference (NIH)ACTG2
Genomic and cartography
GoldenPath hg38 (UCSC)ACTG2  -     chr2:73892966-73919653 +  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACTG2  -     2p13.1   [Description]    (hg19-Feb_2009)
EnsemblACTG2 - 2p13.1 [CytoView hg19]  ACTG2 - 2p13.1 [CytoView hg38]
Mapping of homologs : NCBIACTG2 [Mapview hg19]  ACTG2 [Mapview hg38]
OMIM102545   
Gene and transcription
Genbank (Entrez)AK124338 AK304523 AK310215 AK311011 AK311286
RefSeq transcript (Entrez)NM_001199893 NM_001615
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACTG2
Cluster EST : UnigeneHs.516105 [ NCBI ]
CGAP (NCI)Hs.516105
Alternative Splicing GalleryENSG00000163017
Gene ExpressionACTG2 [ NCBI-GEO ]   ACTG2 [ EBI - ARRAY_EXPRESS ]   ACTG2 [ SEEK ]   ACTG2 [ MEM ]
Gene Expression Viewer (FireBrowse)ACTG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)72
GTEX Portal (Tissue expression)ACTG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63267   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP63267  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP63267
Splice isoforms : SwissVarP63267
PhosPhoSitePlusP63267
Domaine pattern : Prosite (Expaxy)ACTINS_1 (PS00406)    ACTINS_2 (PS00432)    ACTINS_ACT_LIKE (PS01132)   
Domains : Interpro (EBI)Actin    Actin/actin-like_CS    Actin_CS   
Domain families : Pfam (Sanger)Actin (PF00022)   
Domain families : Pfam (NCBI)pfam00022   
Domain families : Smart (EMBL)ACTIN (SM00268)  
Conserved Domain (NCBI)ACTG2
DMDM Disease mutations72
Blocks (Seattle)ACTG2
SuperfamilyP63267
Human Protein AtlasENSG00000163017
Peptide AtlasP63267
HPRD00016
IPIIPI00025416   IPI00917282   IPI00917457   IPI00916212   IPI00917545   IPI00917820   
Protein Interaction databases
DIP (DOE-UCLA)P63267
IntAct (EBI)P63267
FunCoupENSG00000163017
BioGRIDACTG2
STRING (EMBL)ACTG2
ZODIACACTG2
Ontologies - Pathways
QuickGOP63267
Ontology : AmiGOATP binding  extracellular space  cytoplasm  cytosol  muscle contraction  positive regulation of gene expression  lamellipodium  filopodium  myosin filament  cell body  extracellular exosome  cell periphery  blood microparticle  mesenchyme migration  
Ontology : EGO-EBIATP binding  extracellular space  cytoplasm  cytosol  muscle contraction  positive regulation of gene expression  lamellipodium  filopodium  myosin filament  cell body  extracellular exosome  cell periphery  blood microparticle  mesenchyme migration  
Pathways : KEGGVascular smooth muscle contraction   
NDEx NetworkACTG2
Atlas of Cancer Signalling NetworkACTG2
Wikipedia pathwaysACTG2
Orthology - Evolution
OrthoDB72
GeneTree (enSembl)ENSG00000163017
Phylogenetic Trees/Animal Genes : TreeFamACTG2
HOVERGENP63267
HOGENOMP63267
Homologs : HomoloGeneACTG2
Homology/Alignments : Family Browser (UCSC)ACTG2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACTG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACTG2
dbVarACTG2
ClinVarACTG2
1000_GenomesACTG2 
Exome Variant ServerACTG2
ExAC (Exome Aggregation Consortium)ACTG2 (select the gene name)
Genetic variants : HAPMAP72
Genomic Variants (DGV)ACTG2 [DGVbeta]
DECIPHERACTG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACTG2 
Mutations
ICGC Data PortalACTG2 
TCGA Data PortalACTG2 
Broad Tumor PortalACTG2
OASIS PortalACTG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACTG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACTG2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACTG2
DgiDB (Drug Gene Interaction Database)ACTG2
DoCM (Curated mutations)ACTG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACTG2 (select a term)
intoGenACTG2
Cancer3DACTG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM102545   
Orphanet1209    2113    15007   
MedgenACTG2
Genetic Testing Registry ACTG2
NextProtP63267 [Medical]
TSGene72
GENETestsACTG2
Target ValidationACTG2
Huge Navigator ACTG2 [HugePedia]
snp3D : Map Gene to Disease72
BioCentury BCIQACTG2
ClinGenACTG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD72
Chemical/Pharm GKB GenePA24469
Clinical trialACTG2
Miscellaneous
canSAR (ICR)ACTG2 (select the gene name)
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACTG2
EVEXACTG2
GoPubMedACTG2
iHOPACTG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:22:36 CEST 2017

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