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ACTR1A (actin related protein 1A)

Identity

Alias (NCBI)ARP1
Arp1A
CTRN1
HGNC (Hugo) ACTR1A
HGNC Alias symbARP1
Arp1A
HGNC Alias namecentractin alpha
HGNC Previous nameARP1 (actin-related protein 1, yeast) homolog A (centractin alpha)
 ARP1 actin-related protein 1 homolog A, centractin alpha
 ARP1 actin related protein 1 homolog A
LocusID (NCBI) 10121
Atlas_Id 563
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 102479229 and ends at 102502712 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTR1A (10q24.32) / ACTR1A (10q24.32)ACTR1A (10q24.32) / MIPOL1 (14q13.3)ACTR1A (10q24.32) / OBFC1 (10q24.33)
ACTR1A (10q24.32) / SLC2A1 (1p34.2)ARL3 (10q24.32) / ACTR1A (10q24.32)BOC (3q13.2) / ACTR1A (10q24.32)
MIPOL1 (14q13.3) / ACTR1A (10q24.32)ACTR1A 10q24.32 / OBFC1 10q24.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ACTR1A   167
Cards
Entrez_Gene (NCBI)ACTR1A    actin related protein 1A
AliasesARP1; Arp1A; CTRN1
GeneCards (Weizmann)ACTR1A
Ensembl hg19 (Hinxton)ENSG00000138107 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138107 [Gene_View]  ENSG00000138107 [Sequence]  chr10:102479229-102502712 [Contig_View]  ACTR1A [Vega]
ICGC DataPortalENSG00000138107
TCGA cBioPortalACTR1A
AceView (NCBI)ACTR1A
Genatlas (Paris)ACTR1A
SOURCE (Princeton)ACTR1A
Genetics Home Reference (NIH)ACTR1A
Genomic and cartography
GoldenPath hg38 (UCSC)ACTR1A  -     chr10:102479229-102502712 -  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACTR1A  -     10q24.32   [Description]    (hg19-Feb_2009)
GoldenPathACTR1A - 10q24.32 [CytoView hg19]  ACTR1A - 10q24.32 [CytoView hg38]
ImmunoBaseENSG00000138107
Genome Data Viewer NCBIACTR1A [Mapview hg19]  
OMIM605143   
Gene and transcription
Genbank (Entrez)AK096085 AK297362 AK297620 AK302072 AK312506
RefSeq transcript (Entrez)NM_005736
Consensus coding sequences : CCDS (NCBI)ACTR1A
Gene ExpressionACTR1A [ NCBI-GEO ]   ACTR1A [ EBI - ARRAY_EXPRESS ]   ACTR1A [ SEEK ]   ACTR1A [ MEM ]
Gene Expression Viewer (FireBrowse)ACTR1A [ Firebrowse - Broad ]
GenevisibleExpression of ACTR1A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10121
GTEX Portal (Tissue expression)ACTR1A
Human Protein AtlasENSG00000138107-ACTR1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61163   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61163  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61163
PhosPhoSitePlusP61163
Domaine pattern : Prosite (Expaxy)ACTINS_2 (PS00432)    ACTINS_ACT_LIKE (PS01132)   
Domains : Interpro (EBI)Actin    Actin/actin-like_CS    Actin_CS    ATPase_NBD   
Domain families : Pfam (Sanger)Actin (PF00022)   
Domain families : Pfam (NCBI)pfam00022   
Domain families : Smart (EMBL)ACTIN (SM00268)  
Conserved Domain (NCBI)ACTR1A
SuperfamilyP61163
AlphaFold pdb e-kbP61163   
Human Protein Atlas [tissue]ENSG00000138107-ACTR1A [tissue]
HPRD05507
Protein Interaction databases
DIP (DOE-UCLA)P61163
IntAct (EBI)P61163
BioGRIDACTR1A
STRING (EMBL)ACTR1A
ZODIACACTR1A
Ontologies - Pathways
QuickGOP61163
Ontology : AmiGOG2/M transition of mitotic cell cycle  manchette  protein binding  ATP binding  cytoplasm  centrosome  centriole  cytosol  dynactin complex  microtubule associated complex  endoplasmic reticulum to Golgi vesicle-mediated transport  spermatogenesis  regulation of G2/M transition of mitotic cell cycle  microtubule cytoskeleton  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPI-coated vesicle  extracellular exosome  ciliary basal body-plasma membrane docking  cell cortex region  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  manchette  protein binding  ATP binding  cytoplasm  centrosome  centriole  cytosol  dynactin complex  microtubule associated complex  endoplasmic reticulum to Golgi vesicle-mediated transport  spermatogenesis  regulation of G2/M transition of mitotic cell cycle  microtubule cytoskeleton  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPI-coated vesicle  extracellular exosome  ciliary basal body-plasma membrane docking  cell cortex region  
NDEx NetworkACTR1A
Atlas of Cancer Signalling NetworkACTR1A
Wikipedia pathwaysACTR1A
Orthology - Evolution
OrthoDB10121
GeneTree (enSembl)ENSG00000138107
Phylogenetic Trees/Animal Genes : TreeFamACTR1A
Homologs : HomoloGeneACTR1A
Homology/Alignments : Family Browser (UCSC)ACTR1A
Gene fusions - Rearrangements
Fusion : MitelmanACTR1A/OBFC1 [10q24.32/10q24.33]  
Fusion : QuiverACTR1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACTR1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACTR1A
dbVarACTR1A
ClinVarACTR1A
MonarchACTR1A
1000_GenomesACTR1A 
Exome Variant ServerACTR1A
GNOMAD BrowserENSG00000138107
Varsome BrowserACTR1A
ACMGACTR1A variants
VarityP61163
Genomic Variants (DGV)ACTR1A [DGVbeta]
DECIPHERACTR1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACTR1A 
Mutations
ICGC Data PortalACTR1A 
TCGA Data PortalACTR1A 
Broad Tumor PortalACTR1A
OASIS PortalACTR1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACTR1A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DACTR1A
Mutations and Diseases : HGMDACTR1A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaACTR1A
DgiDB (Drug Gene Interaction Database)ACTR1A
DoCM (Curated mutations)ACTR1A
CIViC (Clinical Interpretations of Variants in Cancer)ACTR1A
Cancer3DACTR1A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605143   
Orphanet
DisGeNETACTR1A
MedgenACTR1A
Genetic Testing Registry ACTR1A
NextProtP61163 [Medical]
GENETestsACTR1A
Target ValidationACTR1A
Huge Navigator ACTR1A [HugePedia]
ClinGenACTR1A
Clinical trials, drugs, therapy
MyCancerGenomeACTR1A
Protein Interactions : CTDACTR1A
Pharm GKB GenePA24486
PharosP61163
Clinical trialACTR1A
Miscellaneous
canSAR (ICR)ACTR1A
HarmonizomeACTR1A
DataMed IndexACTR1A
Probes
Litterature
PubMed110 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXACTR1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:58:20 CEST 2021

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