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ACTR1B (ARP1 actin related protein 1 homolog B)

Identity

Alias_namesCTRN2
ARP1 (actin-related protein 1
Alias_symbol (synonym)Arp1B
Other aliasARP1B
PC3
HGNC (Hugo) ACTR1B
LocusID (NCBI) 10120
Atlas_Id 50144
Location 2q11.2  [Link to chromosome band 2q11]
Location_base_pair Starts at 97655939 and ends at 97664098 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACTR1B (2q11.2) / FAM53C (5q31.2)ACTR1B (2q11.2) / HLA-B (6p21.33)ACTR1B (2q11.2) / RDX (11q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACTR1B   168
Cards
Entrez_Gene (NCBI)ACTR1B  10120  ARP1 actin related protein 1 homolog B
AliasesARP1B; CTRN2; PC3
GeneCards (Weizmann)ACTR1B
Ensembl hg19 (Hinxton)ENSG00000115073 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115073 [Gene_View]  chr2:97655939-97664098 [Contig_View]  ACTR1B [Vega]
ICGC DataPortalENSG00000115073
TCGA cBioPortalACTR1B
AceView (NCBI)ACTR1B
Genatlas (Paris)ACTR1B
WikiGenes10120
SOURCE (Princeton)ACTR1B
Genetics Home Reference (NIH)ACTR1B
Genomic and cartography
GoldenPath hg38 (UCSC)ACTR1B  -     chr2:97655939-97664098 -  2q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACTR1B  -     2q11.2   [Description]    (hg19-Feb_2009)
EnsemblACTR1B - 2q11.2 [CytoView hg19]  ACTR1B - 2q11.2 [CytoView hg38]
Mapping of homologs : NCBIACTR1B [Mapview hg19]  ACTR1B [Mapview hg38]
OMIM605144   
Gene and transcription
Genbank (Entrez)BC004374 BC006372 BC010090 BC025274 DQ893438
RefSeq transcript (Entrez)NM_005735
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACTR1B
Cluster EST : UnigeneHs.98791 [ NCBI ]
CGAP (NCI)Hs.98791
Alternative Splicing GalleryENSG00000115073
Gene ExpressionACTR1B [ NCBI-GEO ]   ACTR1B [ EBI - ARRAY_EXPRESS ]   ACTR1B [ SEEK ]   ACTR1B [ MEM ]
Gene Expression Viewer (FireBrowse)ACTR1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10120
GTEX Portal (Tissue expression)ACTR1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP42025   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP42025  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP42025
Splice isoforms : SwissVarP42025
PhosPhoSitePlusP42025
Domaine pattern : Prosite (Expaxy)ACTINS_2 (PS00432)    ACTINS_ACT_LIKE (PS01132)   
Domains : Interpro (EBI)Actin    Actin/actin-like_CS    Actin_CS    Arp1   
Domain families : Pfam (Sanger)Actin (PF00022)   
Domain families : Pfam (NCBI)pfam00022   
Domain families : Smart (EMBL)ACTIN (SM00268)  
Conserved Domain (NCBI)ACTR1B
DMDM Disease mutations10120
Blocks (Seattle)ACTR1B
SuperfamilyP42025
Human Protein AtlasENSG00000115073
Peptide AtlasP42025
HPRD05508
IPIIPI00029469   IPI00917682   
Protein Interaction databases
DIP (DOE-UCLA)P42025
IntAct (EBI)P42025
FunCoupENSG00000115073
BioGRIDACTR1B
STRING (EMBL)ACTR1B
ZODIACACTR1B
Ontologies - Pathways
QuickGOP42025
Ontology : AmiGOprotein binding  ATP binding  extracellular region  cytoplasm  centrosome  cytosol  dynactin complex  microtubule cytoskeleton  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  secretory granule lumen  neutrophil degranulation  extracellular exosome  ficolin-1-rich granule lumen  
Ontology : EGO-EBIprotein binding  ATP binding  extracellular region  cytoplasm  centrosome  cytosol  dynactin complex  microtubule cytoskeleton  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  secretory granule lumen  neutrophil degranulation  extracellular exosome  ficolin-1-rich granule lumen  
NDEx NetworkACTR1B
Atlas of Cancer Signalling NetworkACTR1B
Wikipedia pathwaysACTR1B
Orthology - Evolution
OrthoDB10120
GeneTree (enSembl)ENSG00000115073
Phylogenetic Trees/Animal Genes : TreeFamACTR1B
HOVERGENP42025
HOGENOMP42025
Homologs : HomoloGeneACTR1B
Homology/Alignments : Family Browser (UCSC)ACTR1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACTR1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACTR1B
dbVarACTR1B
ClinVarACTR1B
1000_GenomesACTR1B 
Exome Variant ServerACTR1B
ExAC (Exome Aggregation Consortium)ACTR1B (select the gene name)
Genetic variants : HAPMAP10120
Genomic Variants (DGV)ACTR1B [DGVbeta]
DECIPHERACTR1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACTR1B 
Mutations
ICGC Data PortalACTR1B 
TCGA Data PortalACTR1B 
Broad Tumor PortalACTR1B
OASIS PortalACTR1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACTR1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACTR1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACTR1B
DgiDB (Drug Gene Interaction Database)ACTR1B
DoCM (Curated mutations)ACTR1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACTR1B (select a term)
intoGenACTR1B
Cancer3DACTR1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605144   
Orphanet
MedgenACTR1B
Genetic Testing Registry ACTR1B
NextProtP42025 [Medical]
TSGene10120
GENETestsACTR1B
Target ValidationACTR1B
Huge Navigator ACTR1B [HugePedia]
snp3D : Map Gene to Disease10120
BioCentury BCIQACTR1B
ClinGenACTR1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10120
Chemical/Pharm GKB GenePA24487
Clinical trialACTR1B
Miscellaneous
canSAR (ICR)ACTR1B (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACTR1B
EVEXACTR1B
GoPubMedACTR1B
iHOPACTR1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:56:03 CEST 2017

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