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ACTR3C (ARP3 actin-related protein 3 homolog C)

Identity

Alias_namesARP3 actin-related protein 3 homolog C (yeast)
Alias_symbol (synonym)ARP11
Other alias
HGNC (Hugo) ACTR3C
LocusID (NCBI) 653857
Atlas_Id 54105
Location 7q36.1  [Link to chromosome band 7q36]
Location_base_pair Starts at 149944301 and ends at 150020758 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACTR3C (7q36.1) / SFTPB (2p11.2)ACTR3C (7q36.1) / SORCS1 (10q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ACTR3C   37282
Cards
Entrez_Gene (NCBI)ACTR3C  653857  ARP3 actin-related protein 3 homolog C
AliasesARP11
GeneCards (Weizmann)ACTR3C
Ensembl hg19 (Hinxton)ENSG00000106526 [Gene_View]  chr7:149944301-150020758 [Contig_View]  ACTR3C [Vega]
Ensembl hg38 (Hinxton)ENSG00000106526 [Gene_View]  chr7:149944301-150020758 [Contig_View]  ACTR3C [Vega]
ICGC DataPortalENSG00000106526
TCGA cBioPortalACTR3C
AceView (NCBI)ACTR3C
Genatlas (Paris)ACTR3C
WikiGenes653857
SOURCE (Princeton)ACTR3C
Genetics Home Reference (NIH)ACTR3C
Genomic and cartography
GoldenPath hg19 (UCSC)ACTR3C  -     chr7:149944301-150020758 -  7q36.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACTR3C  -     7q36.1   [Description]    (hg38-Dec_2013)
EnsemblACTR3C - 7q36.1 [CytoView hg19]  ACTR3C - 7q36.1 [CytoView hg38]
Mapping of homologs : NCBIACTR3C [Mapview hg19]  ACTR3C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB039791 AK130039 BM674900 BX640643 DA868104
RefSeq transcript (Entrez)NM_001164458 NM_001164459
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007933 NW_004929333
Consensus coding sequences : CCDS (NCBI)ACTR3C
Cluster EST : UnigeneHs.664579 [ NCBI ]
CGAP (NCI)Hs.664579
Alternative Splicing GalleryENSG00000106526
Gene ExpressionACTR3C [ NCBI-GEO ]   ACTR3C [ EBI - ARRAY_EXPRESS ]   ACTR3C [ SEEK ]   ACTR3C [ MEM ]
Gene Expression Viewer (FireBrowse)ACTR3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)653857
GTEX Portal (Tissue expression)ACTR3C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0K3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0K3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0K3
Splice isoforms : SwissVarQ9C0K3
PhosPhoSitePlusQ9C0K3
Domains : Interpro (EBI)Actin    Arp3_met   
Domain families : Pfam (Sanger)Actin (PF00022)   
Domain families : Pfam (NCBI)pfam00022   
Domain families : Smart (EMBL)ACTIN (SM00268)  
Conserved Domain (NCBI)ACTR3C
DMDM Disease mutations653857
Blocks (Seattle)ACTR3C
SuperfamilyQ9C0K3
Human Protein AtlasENSG00000106526
Peptide AtlasQ9C0K3
IPIIPI00946655   IPI00947074   IPI00442839   IPI00642069   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0K3
IntAct (EBI)Q9C0K3
FunCoupENSG00000106526
BioGRIDACTR3C
STRING (EMBL)ACTR3C
ZODIACACTR3C
Ontologies - Pathways
QuickGOQ9C0K3
Ontology : AmiGOmolecular_function  actin binding  ATP binding  Arp2/3 protein complex  biological_process  Arp2/3 complex-mediated actin nucleation  extracellular exosome  
Ontology : EGO-EBImolecular_function  actin binding  ATP binding  Arp2/3 protein complex  biological_process  Arp2/3 complex-mediated actin nucleation  extracellular exosome  
NDEx NetworkACTR3C
Atlas of Cancer Signalling NetworkACTR3C
Wikipedia pathwaysACTR3C
Orthology - Evolution
OrthoDB653857
GeneTree (enSembl)ENSG00000106526
Phylogenetic Trees/Animal Genes : TreeFamACTR3C
HOVERGENQ9C0K3
HOGENOMQ9C0K3
Homologs : HomoloGeneACTR3C
Homology/Alignments : Family Browser (UCSC)ACTR3C
Gene fusions - Rearrangements
Fusion : MitelmanACTR3C/SORCS1 [7q36.1/10q25.1]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACTR3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACTR3C
dbVarACTR3C
ClinVarACTR3C
1000_GenomesACTR3C 
Exome Variant ServerACTR3C
ExAC (Exome Aggregation Consortium)ACTR3C (select the gene name)
Genetic variants : HAPMAP653857
Genomic Variants (DGV)ACTR3C [DGVbeta]
DECIPHER (Syndromes)7:149944301-150020758  ENSG00000106526
CONAN: Copy Number AnalysisACTR3C 
Mutations
ICGC Data PortalACTR3C 
TCGA Data PortalACTR3C 
Broad Tumor PortalACTR3C
OASIS PortalACTR3C [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDACTR3C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACTR3C
DgiDB (Drug Gene Interaction Database)ACTR3C
DoCM (Curated mutations)ACTR3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACTR3C (select a term)
intoGenACTR3C
Cancer3DACTR3C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenACTR3C
Genetic Testing Registry ACTR3C
NextProtQ9C0K3 [Medical]
TSGene653857
GENETestsACTR3C
Huge Navigator ACTR3C [HugePedia]
snp3D : Map Gene to Disease653857
BioCentury BCIQACTR3C
ClinGenACTR3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD653857
Chemical/Pharm GKB GenePA165617588
Clinical trialACTR3C
Miscellaneous
canSAR (ICR)ACTR3C (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACTR3C
EVEXACTR3C
GoPubMedACTR3C
iHOPACTR3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:51:29 CEST 2017

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