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ACTR8 (ARP8 actin related protein 8 homolog)

Identity

Alias_namesARP8 (actin-related protein 8
Alias_symbol (synonym)INO80N
Other aliasARP8
hArp8
HGNC (Hugo) ACTR8
LocusID (NCBI) 93973
Atlas_Id 52229
Location 3p21.1  [Link to chromosome band 3p21]
Location_base_pair Starts at 53867066 and ends at 53882202 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTR8 (3p21.1) / ANP32A (15q23)ACTR8 (3p21.1) / NDUFC2-KCTD14 (11q14.1)NTRK3 (15q25.3) / ACTR8 (3p21.1)
STRN3 (14q12) / ACTR8 (3p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACTR8   14672
Cards
Entrez_Gene (NCBI)ACTR8  93973  ARP8 actin related protein 8 homolog
AliasesARP8; INO80N; hArp8
GeneCards (Weizmann)ACTR8
Ensembl hg19 (Hinxton)ENSG00000113812 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113812 [Gene_View]  chr3:53867066-53882202 [Contig_View]  ACTR8 [Vega]
ICGC DataPortalENSG00000113812
TCGA cBioPortalACTR8
AceView (NCBI)ACTR8
Genatlas (Paris)ACTR8
WikiGenes93973
SOURCE (Princeton)ACTR8
Genetics Home Reference (NIH)ACTR8
Genomic and cartography
GoldenPath hg38 (UCSC)ACTR8  -     chr3:53867066-53882202 -  3p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACTR8  -     3p21.1   [Description]    (hg19-Feb_2009)
EnsemblACTR8 - 3p21.1 [CytoView hg19]  ACTR8 - 3p21.1 [CytoView hg38]
Mapping of homologs : NCBIACTR8 [Mapview hg19]  ACTR8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK022996 AK026232 AK094507 BC032744 BU070174
RefSeq transcript (Entrez)NM_022899
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACTR8
Cluster EST : UnigeneHs.412186 [ NCBI ]
CGAP (NCI)Hs.412186
Alternative Splicing GalleryENSG00000113812
Gene ExpressionACTR8 [ NCBI-GEO ]   ACTR8 [ EBI - ARRAY_EXPRESS ]   ACTR8 [ SEEK ]   ACTR8 [ MEM ]
Gene Expression Viewer (FireBrowse)ACTR8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)93973
GTEX Portal (Tissue expression)ACTR8
Human Protein AtlasENSG00000113812-ACTR8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H981   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H981  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H981
Splice isoforms : SwissVarQ9H981
PhosPhoSitePlusQ9H981
Domains : Interpro (EBI)Actin    Arp8/plant_Arp9   
Domain families : Pfam (Sanger)Actin (PF00022)   
Domain families : Pfam (NCBI)pfam00022   
Domain families : Smart (EMBL)ACTIN (SM00268)  
Conserved Domain (NCBI)ACTR8
DMDM Disease mutations93973
Blocks (Seattle)ACTR8
PDB (SRS)4FO0   
PDB (PDBSum)4FO0   
PDB (IMB)4FO0   
PDB (RSDB)4FO0   
Structural Biology KnowledgeBase4FO0   
SCOP (Structural Classification of Proteins)4FO0   
CATH (Classification of proteins structures)4FO0   
SuperfamilyQ9H981
Human Protein Atlas [tissue]ENSG00000113812-ACTR8 [tissue]
Peptide AtlasQ9H981
HPRD09792
IPIIPI00025646   IPI00794608   IPI00166798   IPI00983950   
Protein Interaction databases
DIP (DOE-UCLA)Q9H981
IntAct (EBI)Q9H981
FunCoupENSG00000113812
BioGRIDACTR8
STRING (EMBL)ACTR8
ZODIACACTR8
Ontologies - Pathways
QuickGOQ9H981
Ontology : AmiGOprotein binding  ATP binding  nucleus  nucleoplasm  centrosome  DNA repair  DNA recombination  chromatin remodeling  transcription, DNA-templated  regulation of transcription, DNA-templated  cell cycle  protein deubiquitination  Ino80 complex  cell division  
Ontology : EGO-EBIprotein binding  ATP binding  nucleus  nucleoplasm  centrosome  DNA repair  DNA recombination  chromatin remodeling  transcription, DNA-templated  regulation of transcription, DNA-templated  cell cycle  protein deubiquitination  Ino80 complex  cell division  
NDEx NetworkACTR8
Atlas of Cancer Signalling NetworkACTR8
Wikipedia pathwaysACTR8
Orthology - Evolution
OrthoDB93973
GeneTree (enSembl)ENSG00000113812
Phylogenetic Trees/Animal Genes : TreeFamACTR8
HOVERGENQ9H981
HOGENOMQ9H981
Homologs : HomoloGeneACTR8
Homology/Alignments : Family Browser (UCSC)ACTR8
Gene fusions - Rearrangements
Tumor Fusion PortalACTR8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACTR8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACTR8
dbVarACTR8
ClinVarACTR8
1000_GenomesACTR8 
Exome Variant ServerACTR8
ExAC (Exome Aggregation Consortium)ENSG00000113812
GNOMAD BrowserENSG00000113812
Genetic variants : HAPMAP93973
Genomic Variants (DGV)ACTR8 [DGVbeta]
DECIPHERACTR8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACTR8 
Mutations
ICGC Data PortalACTR8 
TCGA Data PortalACTR8 
Broad Tumor PortalACTR8
OASIS PortalACTR8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACTR8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACTR8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACTR8
DgiDB (Drug Gene Interaction Database)ACTR8
DoCM (Curated mutations)ACTR8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACTR8 (select a term)
intoGenACTR8
Cancer3DACTR8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETACTR8
MedgenACTR8
Genetic Testing Registry ACTR8
NextProtQ9H981 [Medical]
TSGene93973
GENETestsACTR8
Target ValidationACTR8
Huge Navigator ACTR8 [HugePedia]
snp3D : Map Gene to Disease93973
BioCentury BCIQACTR8
ClinGenACTR8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD93973
Chemical/Pharm GKB GenePA24491
Clinical trialACTR8
Miscellaneous
canSAR (ICR)ACTR8 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACTR8
EVEXACTR8
GoPubMedACTR8
iHOPACTR8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:01:59 CET 2017

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