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ACY3 (aminoacylase 3)

Identity

Alias_namesaspartoacylase (aminoacylase) 3
Alias_symbol (synonym)HCBP1
MGC9740
ACY-3
Other alias
HGNC (Hugo) ACY3
LocusID (NCBI) 91703
Atlas_Id 60129
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67642555 and ends at 67650659 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACY3   24104
Cards
Entrez_Gene (NCBI)ACY3  91703  aminoacylase 3
AliasesACY-3; HCBP1
GeneCards (Weizmann)ACY3
Ensembl hg19 (Hinxton)ENSG00000132744 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132744 [Gene_View]  chr11:67642555-67650659 [Contig_View]  ACY3 [Vega]
ICGC DataPortalENSG00000132744
TCGA cBioPortalACY3
AceView (NCBI)ACY3
Genatlas (Paris)ACY3
WikiGenes91703
SOURCE (Princeton)ACY3
Genetics Home Reference (NIH)ACY3
Genomic and cartography
GoldenPath hg38 (UCSC)ACY3  -     chr11:67642555-67650659 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ACY3  -     11q13.2   [Description]    (hg19-Feb_2009)
EnsemblACY3 - 11q13.2 [CytoView hg19]  ACY3 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIACY3 [Mapview hg19]  ACY3 [Mapview hg38]
OMIM614413   
Gene and transcription
Genbank (Entrez)AF359506 AK308710 AY032593 AY040761 AY169233
RefSeq transcript (Entrez)NM_080658
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ACY3
Cluster EST : UnigeneHs.126265 [ NCBI ]
CGAP (NCI)Hs.126265
Alternative Splicing GalleryENSG00000132744
Gene ExpressionACY3 [ NCBI-GEO ]   ACY3 [ EBI - ARRAY_EXPRESS ]   ACY3 [ SEEK ]   ACY3 [ MEM ]
Gene Expression Viewer (FireBrowse)ACY3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)91703
GTEX Portal (Tissue expression)ACY3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HD9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HD9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HD9
Splice isoforms : SwissVarQ96HD9
Catalytic activity : Enzyme3.5.1.114 [ Enzyme-Expasy ]   3.5.1.1143.5.1.114 [ IntEnz-EBI ]   3.5.1.114 [ BRENDA ]   3.5.1.114 [ KEGG ]   
PhosPhoSitePlusQ96HD9
Domains : Interpro (EBI)Aspartoacylase    Aste_AspA   
Domain families : Pfam (Sanger)AstE_AspA (PF04952)   
Domain families : Pfam (NCBI)pfam04952   
Conserved Domain (NCBI)ACY3
DMDM Disease mutations91703
Blocks (Seattle)ACY3
SuperfamilyQ96HD9
Human Protein AtlasENSG00000132744
Peptide AtlasQ96HD9
HPRD12422
IPIIPI00063025   IPI00382975   IPI00977254   
Protein Interaction databases
DIP (DOE-UCLA)Q96HD9
IntAct (EBI)Q96HD9
FunCoupENSG00000132744
BioGRIDACY3
STRING (EMBL)ACY3
ZODIACACY3
Ontologies - Pathways
QuickGOQ96HD9
Ontology : AmiGOmolecular_function  aminoacylase activity  aminoacylase activity  protein binding  cytosol  xenobiotic metabolic process  biological_process  viral process  apical plasma membrane  hydrolase activity, acting on ester bonds  identical protein binding  metal ion binding  extracellular exosome  
Ontology : EGO-EBImolecular_function  aminoacylase activity  aminoacylase activity  protein binding  cytosol  xenobiotic metabolic process  biological_process  viral process  apical plasma membrane  hydrolase activity, acting on ester bonds  identical protein binding  metal ion binding  extracellular exosome  
Pathways : KEGGAlanine, aspartate and glutamate metabolism    Histidine metabolism   
NDEx NetworkACY3
Atlas of Cancer Signalling NetworkACY3
Wikipedia pathwaysACY3
Orthology - Evolution
OrthoDB91703
GeneTree (enSembl)ENSG00000132744
Phylogenetic Trees/Animal Genes : TreeFamACY3
HOVERGENQ96HD9
HOGENOMQ96HD9
Homologs : HomoloGeneACY3
Homology/Alignments : Family Browser (UCSC)ACY3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACY3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACY3
dbVarACY3
ClinVarACY3
1000_GenomesACY3 
Exome Variant ServerACY3
ExAC (Exome Aggregation Consortium)ACY3 (select the gene name)
Genetic variants : HAPMAP91703
Genomic Variants (DGV)ACY3 [DGVbeta]
DECIPHERACY3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisACY3 
Mutations
ICGC Data PortalACY3 
TCGA Data PortalACY3 
Broad Tumor PortalACY3
OASIS PortalACY3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACY3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACY3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACY3
DgiDB (Drug Gene Interaction Database)ACY3
DoCM (Curated mutations)ACY3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACY3 (select a term)
intoGenACY3
Cancer3DACY3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614413   
Orphanet
MedgenACY3
Genetic Testing Registry ACY3
NextProtQ96HD9 [Medical]
TSGene91703
GENETestsACY3
Target ValidationACY3
Huge Navigator ACY3 [HugePedia]
snp3D : Map Gene to Disease91703
BioCentury BCIQACY3
ClinGenACY3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD91703
Chemical/Pharm GKB GenePA134936640
Clinical trialACY3
Miscellaneous
canSAR (ICR)ACY3 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACY3
EVEXACY3
GoPubMedACY3
iHOPACY3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:08:51 CEST 2017

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