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ADA2 (adenosine deaminase 2)

Identity

Other aliasADGF
CECR1
IDGFL
PAN
SNEDS
HGNC (Hugo) ADA2
LocusID (NCBI) 51816
Atlas_Id 56862
Location 22q11.1  [Link to chromosome band 22q11]
Location_base_pair Starts at 17178790 and ends at 17219585 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADA2   1839
Cards
Entrez_Gene (NCBI)ADA2  51816  adenosine deaminase 2
AliasesADGF; CECR1; IDGFL; PAN; 
SNEDS
GeneCards (Weizmann)ADA2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr22:17178790-17219585 [Contig_View]  ADA2 [Vega]
TCGA cBioPortalADA2
AceView (NCBI)ADA2
Genatlas (Paris)ADA2
WikiGenes51816
SOURCE (Princeton)ADA2
Genetics Home Reference (NIH)ADA2
Genomic and cartography
GoldenPath hg38 (UCSC)ADA2  -     chr22:17178790-17219585 -  22q11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADA2  -     22q11.1   [Description]    (hg19-Feb_2009)
EnsemblADA2 - 22q11.1 [CytoView hg19]  ADA2 - 22q11.1 [CytoView hg38]
Mapping of homologs : NCBIADA2 [Mapview hg19]  ADA2 [Mapview hg38]
OMIM182410   607575   615688   
Gene and transcription
Genbank (Entrez)AB209648 AF190746 AI523928 AK027682 AK074702
RefSeq transcript (Entrez)NM_001282225 NM_001282226 NM_001282227 NM_001282228 NM_001282229 NM_017424 NM_177405
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADA2
Cluster EST : UnigeneHs.637274 [ NCBI ]
CGAP (NCI)Hs.637274
Gene ExpressionADA2 [ NCBI-GEO ]   ADA2 [ EBI - ARRAY_EXPRESS ]   ADA2 [ SEEK ]   ADA2 [ MEM ]
Gene Expression Viewer (FireBrowse)ADA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51816
GTEX Portal (Tissue expression)ADA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZK5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZK5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZK5
Splice isoforms : SwissVarQ9NZK5
Catalytic activity : Enzyme3.5.4.4 [ Enzyme-Expasy ]   3.5.4.43.5.4.4 [ IntEnz-EBI ]   3.5.4.4 [ BRENDA ]   3.5.4.4 [ KEGG ]   
PhosPhoSitePlusQ9NZK5
Domains : Interpro (EBI)A/AMP_deaminase_dom    A_deaminase_N    ADGF    Metal_Hydrolase   
Domain families : Pfam (Sanger)A_deaminase (PF00962)    A_deaminase_N (PF08451)   
Domain families : Pfam (NCBI)pfam00962    pfam08451   
Conserved Domain (NCBI)ADA2
DMDM Disease mutations51816
Blocks (Seattle)ADA2
PDB (SRS)3LGD    3LGG   
PDB (PDBSum)3LGD    3LGG   
PDB (IMB)3LGD    3LGG   
PDB (RSDB)3LGD    3LGG   
Structural Biology KnowledgeBase3LGD    3LGG   
SCOP (Structural Classification of Proteins)3LGD    3LGG   
CATH (Classification of proteins structures)3LGD    3LGG   
SuperfamilyQ9NZK5
Peptide AtlasQ9NZK5
IPIIPI00303071   IPI00252768   IPI01011521   IPI00748521   IPI01012646   IPI00852630   IPI00917635   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZK5
IntAct (EBI)Q9NZK5
BioGRIDADA2
STRING (EMBL)ADA2
ZODIACADA2
Ontologies - Pathways
QuickGOQ9NZK5
Ontology : AmiGOadenosine deaminase activity  adenosine deaminase activity  extracellular region  extracellular space  adenosine catabolic process  multicellular organism development  growth factor activity  heparin binding  zinc ion binding  adenosine receptor binding  azurophil granule lumen  protein homodimerization activity  neutrophil degranulation  proteoglycan binding  cellular protein metabolic process  
Ontology : EGO-EBIadenosine deaminase activity  adenosine deaminase activity  extracellular region  extracellular space  adenosine catabolic process  multicellular organism development  growth factor activity  heparin binding  zinc ion binding  adenosine receptor binding  azurophil granule lumen  protein homodimerization activity  neutrophil degranulation  proteoglycan binding  cellular protein metabolic process  
NDEx NetworkADA2
Atlas of Cancer Signalling NetworkADA2
Wikipedia pathwaysADA2
Orthology - Evolution
OrthoDB51816
Phylogenetic Trees/Animal Genes : TreeFamADA2
HOVERGENQ9NZK5
HOGENOMQ9NZK5
Homologs : HomoloGeneADA2
Homology/Alignments : Family Browser (UCSC)ADA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADA2
dbVarADA2
ClinVarADA2
1000_GenomesADA2 
Exome Variant ServerADA2
ExAC (Exome Aggregation Consortium)ADA2 (select the gene name)
Genetic variants : HAPMAP51816
Genomic Variants (DGV)ADA2 [DGVbeta]
DECIPHERADA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADA2 
Mutations
ICGC Data PortalADA2 
TCGA Data PortalADA2 
Broad Tumor PortalADA2
OASIS PortalADA2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDADA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADA2
DgiDB (Drug Gene Interaction Database)ADA2
DoCM (Curated mutations)ADA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADA2 (select a term)
intoGenADA2
Cancer3DADA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182410    607575    615688   
Orphanet
MedgenADA2
Genetic Testing Registry ADA2
NextProtQ9NZK5 [Medical]
TSGene51816
GENETestsADA2
Target ValidationADA2
Huge Navigator ADA2 [HugePedia]
snp3D : Map Gene to Disease51816
BioCentury BCIQADA2
ClinGenADA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51816
Chemical/Pharm GKB GenePA26382
Clinical trialADA2
Miscellaneous
canSAR (ICR)ADA2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADA2
EVEXADA2
GoPubMedADA2
iHOPADA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 25 18:56:07 CEST 2017

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