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ADAM20 (ADAM metallopeptidase domain 20)

Identity

Alias_namesa disintegrin and metalloproteinase domain 20
Other alias-
HGNC (Hugo) ADAM20
LocusID (NCBI) 8748
Atlas_Id 46737
Location 14q24.2  [Link to chromosome band 14q24]
Location_base_pair Starts at 70522361 and ends at 70535015 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADAM20   199
Cards
Entrez_Gene (NCBI)ADAM20  8748  ADAM metallopeptidase domain 20
Aliases
GeneCards (Weizmann)ADAM20
Ensembl hg19 (Hinxton)ENSG00000134007 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134007 [Gene_View]  chr14:70522361-70535015 [Contig_View]  ADAM20 [Vega]
ICGC DataPortalENSG00000134007
TCGA cBioPortalADAM20
AceView (NCBI)ADAM20
Genatlas (Paris)ADAM20
WikiGenes8748
SOURCE (Princeton)ADAM20
Genetics Home Reference (NIH)ADAM20
Genomic and cartography
GoldenPath hg38 (UCSC)ADAM20  -     chr14:70522361-70535015 -  14q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADAM20  -     14q24.2   [Description]    (hg19-Feb_2009)
EnsemblADAM20 - 14q24.2 [CytoView hg19]  ADAM20 - 14q24.2 [CytoView hg38]
Mapping of homologs : NCBIADAM20 [Mapview hg19]  ADAM20 [Mapview hg38]
OMIM603712   
Gene and transcription
Genbank (Entrez)AA400588 AF029899 BC025378 EU176278
RefSeq transcript (Entrez)NM_003814
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADAM20
Cluster EST : UnigeneHs.177984 [ NCBI ]
CGAP (NCI)Hs.177984
Alternative Splicing GalleryENSG00000134007
Gene ExpressionADAM20 [ NCBI-GEO ]   ADAM20 [ EBI - ARRAY_EXPRESS ]   ADAM20 [ SEEK ]   ADAM20 [ MEM ]
Gene Expression Viewer (FireBrowse)ADAM20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8748
GTEX Portal (Tissue expression)ADAM20
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43506   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43506  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43506
Splice isoforms : SwissVarO43506
Catalytic activity : Enzyme3.4.24.- [ Enzyme-Expasy ]   3.4.24.-3.4.24.- [ IntEnz-EBI ]   3.4.24.- [ BRENDA ]   3.4.24.- [ KEGG ]   
PhosPhoSitePlusO43506
Domaine pattern : Prosite (Expaxy)ADAM_MEPRO (PS50215)    DISINTEGRIN_1 (PS00427)    DISINTEGRIN_2 (PS50214)    ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)ADAM_Cys-rich    Disintegrin_CS    Disintegrin_dom    MetalloPept_cat_dom    Peptidase_M12B    Peptidase_M12B_N    Reprolysin_adamalysin   
Domain families : Pfam (Sanger)ADAM_CR (PF08516)    Disintegrin (PF00200)    Pep_M12B_propep (PF01562)    Reprolysin (PF01421)   
Domain families : Pfam (NCBI)pfam08516    pfam00200    pfam01562    pfam01421   
Domain families : Smart (EMBL)ACR (SM00608)  DISIN (SM00050)  
Conserved Domain (NCBI)ADAM20
DMDM Disease mutations8748
Blocks (Seattle)ADAM20
SuperfamilyO43506
Human Protein AtlasENSG00000134007
Peptide AtlasO43506
HPRD04754
IPIIPI00306205   
Protein Interaction databases
DIP (DOE-UCLA)O43506
IntAct (EBI)O43506
FunCoupENSG00000134007
BioGRIDADAM20
STRING (EMBL)ADAM20
ZODIACADAM20
Ontologies - Pathways
QuickGOO43506
Ontology : AmiGOmetalloendopeptidase activity  plasma membrane  proteolysis  single fertilization  binding of sperm to zona pellucida  metallopeptidase activity  integral component of membrane  metal ion binding  
Ontology : EGO-EBImetalloendopeptidase activity  plasma membrane  proteolysis  single fertilization  binding of sperm to zona pellucida  metallopeptidase activity  integral component of membrane  metal ion binding  
NDEx NetworkADAM20
Atlas of Cancer Signalling NetworkADAM20
Wikipedia pathwaysADAM20
Orthology - Evolution
OrthoDB8748
GeneTree (enSembl)ENSG00000134007
Phylogenetic Trees/Animal Genes : TreeFamADAM20
HOVERGENO43506
HOGENOMO43506
Homologs : HomoloGeneADAM20
Homology/Alignments : Family Browser (UCSC)ADAM20
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADAM20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADAM20
dbVarADAM20
ClinVarADAM20
1000_GenomesADAM20 
Exome Variant ServerADAM20
ExAC (Exome Aggregation Consortium)ADAM20 (select the gene name)
Genetic variants : HAPMAP8748
Genomic Variants (DGV)ADAM20 [DGVbeta]
DECIPHERADAM20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADAM20 
Mutations
ICGC Data PortalADAM20 
TCGA Data PortalADAM20 
Broad Tumor PortalADAM20
OASIS PortalADAM20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADAM20  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADAM20
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADAM20
DgiDB (Drug Gene Interaction Database)ADAM20
DoCM (Curated mutations)ADAM20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADAM20 (select a term)
intoGenADAM20
Cancer3DADAM20(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603712   
Orphanet
MedgenADAM20
Genetic Testing Registry ADAM20
NextProtO43506 [Medical]
TSGene8748
GENETestsADAM20
Target ValidationADAM20
Huge Navigator ADAM20 [HugePedia]
snp3D : Map Gene to Disease8748
BioCentury BCIQADAM20
ClinGenADAM20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8748
Chemical/Pharm GKB GenePA24516
Clinical trialADAM20
Miscellaneous
canSAR (ICR)ADAM20 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADAM20
EVEXADAM20
GoPubMedADAM20
iHOPADAM20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:22:43 CEST 2017

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