Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ADAM32 (ADAM metallopeptidase domain 32)

Identity

Alias (NCBI)-
HGNC (Hugo) ADAM32
HGNC Previous namea disintegrin and metalloproteinase domain 32
LocusID (NCBI) 203102
Atlas_Id 60137
Location 8p11.22  [Link to chromosome band 8p11]
Location_base_pair Starts at 39107529 and ends at 39284917 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAM32 (8p11.22) / ZNF251 (8q24.3)FBXO16 (8p21.1) / ADAM32 (8p11.22)RPAP3 (12q13.11) / ADAM32 (8p11.22)
WHSC1L1 (8p11.23) / ADAM32 (8p11.22)FBXO16 ADAM32WHSC1L1 ADAM32
RPAP3 ADAM32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  t(8;8)(p11;p12) GTF2E2/ADAM32
t(8;8)(p11;p21) FBXO16/ADAM32
t(8;8)(p11;q24) ADAM32/ZNF251
t(8;10)(p11;q26) IKZF5/ADAM32
t(8;12)(p11;q13) RPAP3/ADAM32

External links

Nomenclature
HGNC (Hugo)ADAM32   15479
Cards
Entrez_Gene (NCBI)ADAM32    ADAM metallopeptidase domain 32
Aliases
GeneCards (Weizmann)ADAM32
Ensembl hg19 (Hinxton)ENSG00000197140 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197140 [Gene_View]  ENSG00000197140 [Sequence]  chr8:39107529-39284917 [Contig_View]  ADAM32 [Vega]
ICGC DataPortalENSG00000197140
TCGA cBioPortalADAM32
AceView (NCBI)ADAM32
Genatlas (Paris)ADAM32
SOURCE (Princeton)ADAM32
Genetics Home Reference (NIH)ADAM32
Genomic and cartography
GoldenPath hg38 (UCSC)ADAM32  -     chr8:39107529-39284917 +  8p11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADAM32  -     8p11.22   [Description]    (hg19-Feb_2009)
GoldenPathADAM32 - 8p11.22 [CytoView hg19]  ADAM32 - 8p11.22 [CytoView hg38]
ImmunoBaseENSG00000197140
genome Data Viewer NCBIADAM32 [Mapview hg19]  
OMIM618602   
Gene and transcription
Genbank (Entrez)AB209690 AK122608 AK129810 AK131038 AK300148
RefSeq transcript (Entrez)NM_001313994 NM_145004
RefSeq genomic (Entrez)NC_000008 NT_187577
Consensus coding sequences : CCDS (NCBI)ADAM32
Alternative Splicing GalleryENSG00000197140
Gene ExpressionADAM32 [ NCBI-GEO ]   ADAM32 [ EBI - ARRAY_EXPRESS ]   ADAM32 [ SEEK ]   ADAM32 [ MEM ]
Gene Expression Viewer (FireBrowse)ADAM32 [ Firebrowse - Broad ]
GenevisibleExpression of ADAM32 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)203102
GTEX Portal (Tissue expression)ADAM32
Human Protein AtlasENSG00000197140-ADAM32 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TC27   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TC27  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TC27
Splice isoforms : SwissVarQ8TC27
PhosPhoSitePlusQ8TC27
Domaine pattern : Prosite (Expaxy)ADAM_MEPRO (PS50215)    DISINTEGRIN_1 (PS00427)    DISINTEGRIN_2 (PS50214)    EGF_2 (PS01186)    EGF_3 (PS50026)   
Domains : Interpro (EBI)ADAM_Cys-rich    Disintegrin_CS    Disintegrin_dom    Disintegrin_dom_sf    EGF-like_CS    EGF-like_dom    MetalloPept_cat_dom_sf    Peptidase_M12B    Peptidase_M12B_N    Reprolysin_adamalysin   
Domain families : Pfam (Sanger)ADAM_CR (PF08516)    Disintegrin (PF00200)    Pep_M12B_propep (PF01562)    Reprolysin (PF01421)   
Domain families : Pfam (NCBI)pfam08516    pfam00200    pfam01562    pfam01421   
Domain families : Smart (EMBL)ACR (SM00608)  DISIN (SM00050)  
Conserved Domain (NCBI)ADAM32
Blocks (Seattle)ADAM32
SuperfamilyQ8TC27
Human Protein Atlas [tissue]ENSG00000197140-ADAM32 [tissue]
Peptide AtlasQ8TC27
HPRD16475
IPIIPI00748886   IPI00442910   IPI00446857   IPI00974392   IPI00985092   IPI00909189   IPI00973564   IPI01021710   IPI00976112   
Protein Interaction databases
DIP (DOE-UCLA)Q8TC27
IntAct (EBI)Q8TC27
BioGRIDADAM32
STRING (EMBL)ADAM32
ZODIACADAM32
Ontologies - Pathways
QuickGOQ8TC27
Ontology : AmiGOmetalloendopeptidase activity  proteolysis  integral component of membrane  
Ontology : EGO-EBImetalloendopeptidase activity  proteolysis  integral component of membrane  
NDEx NetworkADAM32
Atlas of Cancer Signalling NetworkADAM32
Wikipedia pathwaysADAM32
Orthology - Evolution
OrthoDB203102
GeneTree (enSembl)ENSG00000197140
Phylogenetic Trees/Animal Genes : TreeFamADAM32
HOGENOMQ8TC27
Homologs : HomoloGeneADAM32
Homology/Alignments : Family Browser (UCSC)ADAM32
Gene fusions - Rearrangements
Fusion PortalFBXO16 ADAM32
Fusion PortalWHSC1L1 ADAM32
Fusion PortalRPAP3 ADAM32
Fusion : QuiverADAM32
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADAM32 [hg38]
dbVarADAM32
ClinVarADAM32
MonarchADAM32
1000_GenomesADAM32 
Exome Variant ServerADAM32
GNOMAD BrowserENSG00000197140
Varsome BrowserADAM32
Genomic Variants (DGV)ADAM32 [DGVbeta]
DECIPHERADAM32 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADAM32 
Mutations
ICGC Data PortalADAM32 
TCGA Data PortalADAM32 
Broad Tumor PortalADAM32
OASIS PortalADAM32 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADAM32  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DADAM32
Mutations and Diseases : HGMDADAM32
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADAM32
DgiDB (Drug Gene Interaction Database)ADAM32
DoCM (Curated mutations)ADAM32 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADAM32 (select a term)
intoGenADAM32
Cancer3DADAM32(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618602   
Orphanet
DisGeNETADAM32
MedgenADAM32
Genetic Testing Registry ADAM32
NextProtQ8TC27 [Medical]
GENETestsADAM32
Target ValidationADAM32
Huge Navigator ADAM32 [HugePedia]
ClinGenADAM32
Clinical trials, drugs, therapy
MyCancerGenomeADAM32
Protein Interactions : CTD
Pharm GKB GenePA134932610
Clinical trialADAM32
Miscellaneous
canSAR (ICR)ADAM32 (select the gene name)
HarmonizomeADAM32
DataMed IndexADAM32
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADAM32
EVEXADAM32
GoPubMedADAM32
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 5 16:45:09 CET 2020
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.