ADAM33 (ADAM metallopeptidase domain 33)

Identity

Other names	C20orf153
	DJ964F7.1
	DKFZp434K0521
	FLJ35308
	FLJ36751
	MGC149823
	MGC71889
HGNC	ADAM33
Location	20p13
Location_base_pair	Starts at 3596620 and ends at 3610738 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ADAM33   15478
Entrez_Gene	ADAM33  80332  ADAM metallopeptidase domain 33
	Cards
GeneCards	ADAM33
Ensembl	ADAM33 [Search_View]   ENSG00000149451 [Gene_View]
Genatlas	ADAM33
GeneLynx	ADAM33
eGenome	ADAM33
euGene	80332
	Genomic and cartography
GoldenPath	ADAM33  -  20p13   chr20:3596620-3610738 -  20p13   [Description]    (hg18-March_2006)
Ensembl	ADAM33 - 20p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ADAM33
	Gene and transcription
Genbank	AB055891 [ ENTREZ ]
Genbank	AF466287 [ ENTREZ ]
Genbank	AF466289 [ ENTREZ ]
Genbank	AK092627 [ ENTREZ ]
Genbank	AK094070 [ ENTREZ ]
RefSeq	NM_025220 [ SRS ]    NM_025220 [ ENTREZ ]
RefSeq	NM_153202 [ SRS ]    NM_153202 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	ADAM33 AceView - NCBI
Unigene	Hs.173716 [ SRS ]    Hs.173716 [ NCBI ]     HS173716 [ spliceNest ]
Fast-db	3489 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q08AM2 [ SRS]    Q08AM2 [ EXPASY ]     Q08AM2 [ INTERPRO ]     Q08AM2 [ UNIPROT ]
Prosite	PS50215 ADAM_MEPRO [ SRS ]    PS50215 ADAM_MEPRO [ Expasy ]
Prosite	PS00427 DISINTEGRIN_1 [ SRS ]    PS00427 DISINTEGRIN_1 [ Expasy ]
Prosite	PS50214 DISINTEGRIN_2 [ SRS ]    PS50214 DISINTEGRIN_2 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Interpro	IPR006586 ADAM_cysteine [ SRS ]    IPR006586 ADAM_cysteine [ EBI ]
Interpro	IPR001762 Blood-coag_inhib_Disintegrin [ SRS ]    IPR001762 Blood-coag_inhib_Disintegrin [ EBI ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR013111 EGF_extracell [ SRS ]    IPR013111 EGF_extracell [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR001590 Peptidase_M12B [ SRS ]    IPR001590 Peptidase_M12B [ EBI ]
Interpro	IPR002870 Peptidase_M12B_N [ SRS ]    IPR002870 Peptidase_M12B_N [ EBI ]
CluSTr	Q08AM2
Pfam	PF08516 ADAM_CR [ SRS ]    PF08516 ADAM_CR [ Sanger ]    pfam08516 [ NCBI-CDD ]
Pfam	PF00200 Disintegrin [ SRS ]    PF00200 Disintegrin [ Sanger ]    pfam00200 [ NCBI-CDD ]
Pfam	PF07974 EGF_2 [ SRS ]    PF07974 EGF_2 [ Sanger ]    pfam07974 [ NCBI-CDD ]
Pfam	PF01562 Pep_M12B_propep [ SRS ]    PF01562 Pep_M12B_propep [ Sanger ]    pfam01562 [ NCBI-CDD ]
Pfam	PF01421 Reprolysin [ SRS ]    PF01421 Reprolysin [ Sanger ]    pfam01421 [ NCBI-CDD ]
Smart	SM00608 ACR [EMBL]
Smart	SM00050 DISIN [EMBL]
Smart	SM00181 EGF [EMBL]
Prodom	PD000664 Disintegrin[INRA-Toulouse]
Prodom	Q08AM2 Q08AM2_HUMAN [ Domain structure ]   Q08AM2 Q08AM2_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q08AM2
HPRD	06173
	Protein Interaction databases
DIP	Q08AM2
IntAct	Q08AM2
	Polymorphism : SNP, mutations, diseases
OMIM	607114    [ map ]
GENECLINICS	607114
SNP	ADAM33 [dbSNP-NCBI]
SNP	NM_025220 [SNP-NCI]
SNP	NM_153202 [SNP-NCI]
SNP	ADAM33 [GeneSNPs - Utah]  ADAM33] [HGBASE - SRS]
HAPMAP	ADAM33 [HAPMAP]
COSMIC	ADAM33 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ADAM33
	General knowledge
Family Browser	ADAM33 [UCSC Family Browser]
SOURCE	NM_025220
SOURCE	NM_153202
SMD	Hs.173716
SAGE	Hs.173716
GO	metalloendopeptidase activity [Amigo]  metalloendopeptidase activity
GO	metalloendopeptidase activity [Amigo]  metalloendopeptidase activity
GO	proteolysis [Amigo]  proteolysis
GO	proteolysis [Amigo]  proteolysis
GO	integrin-mediated signaling pathway [Amigo]  integrin-mediated signaling pathway
GO	metallopeptidase activity [Amigo]  metallopeptidase activity
GO	zinc ion binding [Amigo]  zinc ion binding
GO	zinc ion binding [Amigo]  zinc ion binding
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	metal ion binding [Amigo]  metal ion binding
PubGene	ADAM33
TreeFam	ADAM33
CTD	80332 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ADAM33 Related clones (RZPD - Berlin)
	PubMed
PubMed	45 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:01:54 2008