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ADAMTSL3 (ADAMTS like 3)

Identity

Alias (NCBI)ADAMTSL-3
HGNC (Hugo) ADAMTSL3
HGNC Alias symbKIAA1233
punctin-2
LocusID (NCBI) 57188
Atlas_Id 47149
Location 15q25.2  [Link to chromosome band 15q25]
Location_base_pair Starts at 83654123 and ends at 84039841 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAMTSL3 (15q25.2) / LYPLA1 (8q11.23)MAP2K5 (15q23) / ADAMTSL3 (15q25.2)MCCC1 (3q27.1) / ADAMTSL3 (15q25.2)
NEDD4 (15q21.3) / ADAMTSL3 (15q25.2)MAP2K5 15q23 / ADAMTSL3 15q25.2MCCC1 3q27.1 / ADAMTSL3 15q25.2
NEDD4 15q21.3 / ADAMTSL3 15q25.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ADAMTSL3   14633
Cards
Entrez_Gene (NCBI)ADAMTSL3    ADAMTS like 3
AliasesADAMTSL-3
GeneCards (Weizmann)ADAMTSL3
Ensembl hg19 (Hinxton)ENSG00000156218 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156218 [Gene_View]  ENSG00000156218 [Sequence]  chr15:83654123-84039841 [Contig_View]  ADAMTSL3 [Vega]
ICGC DataPortalENSG00000156218
TCGA cBioPortalADAMTSL3
AceView (NCBI)ADAMTSL3
Genatlas (Paris)ADAMTSL3
SOURCE (Princeton)ADAMTSL3
Genetics Home Reference (NIH)ADAMTSL3
Genomic and cartography
GoldenPath hg38 (UCSC)ADAMTSL3  -     chr15:83654123-84039841 +  15q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADAMTSL3  -     15q25.2   [Description]    (hg19-Feb_2009)
GoldenPathADAMTSL3 - 15q25.2 [CytoView hg19]  ADAMTSL3 - 15q25.2 [CytoView hg38]
ImmunoBaseENSG00000156218
Genome Data Viewer NCBIADAMTSL3 [Mapview hg19]  
OMIM609199   
Gene and transcription
Genbank (Entrez)AB033059 AF237652 AK092324 AK308845 AL109723
RefSeq transcript (Entrez)NM_001301110 NM_207517
Consensus coding sequences : CCDS (NCBI)ADAMTSL3
Gene ExpressionADAMTSL3 [ NCBI-GEO ]   ADAMTSL3 [ EBI - ARRAY_EXPRESS ]   ADAMTSL3 [ SEEK ]   ADAMTSL3 [ MEM ]
Gene Expression Viewer (FireBrowse)ADAMTSL3 [ Firebrowse - Broad ]
GenevisibleExpression of ADAMTSL3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57188
GTEX Portal (Tissue expression)ADAMTSL3
Human Protein AtlasENSG00000156218-ADAMTSL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP82987   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP82987  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP82987
PhosPhoSitePlusP82987
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    PLAC (PS50900)    TSP1 (PS50092)   
Domains : Interpro (EBI)ADAMTS/ADAMTS-like    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    PLAC    TSP1_rpt    TSP1_rpt_sf   
Domain families : Pfam (Sanger)I-set (PF07679)    PLAC (PF08686)    TSP_1 (PF00090)   
Domain families : Pfam (NCBI)pfam07679    pfam08686    pfam00090   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  TSP1 (SM00209)  
Conserved Domain (NCBI)ADAMTSL3
SuperfamilyP82987
AlphaFold pdb e-kbP82987   
Human Protein Atlas [tissue]ENSG00000156218-ADAMTSL3 [tissue]
HPRD12426
Protein Interaction databases
DIP (DOE-UCLA)P82987
IntAct (EBI)P82987
BioGRIDADAMTSL3
STRING (EMBL)ADAMTSL3
ZODIACADAMTSL3
Ontologies - Pathways
QuickGOP82987
Ontology : AmiGOmetalloendopeptidase activity  protein binding  extracellular region  proteolysis  extracellular matrix organization  extracellular matrix  intracellular membrane-bounded organelle  
Ontology : EGO-EBImetalloendopeptidase activity  protein binding  extracellular region  proteolysis  extracellular matrix organization  extracellular matrix  intracellular membrane-bounded organelle  
NDEx NetworkADAMTSL3
Atlas of Cancer Signalling NetworkADAMTSL3
Wikipedia pathwaysADAMTSL3
Orthology - Evolution
OrthoDB57188
GeneTree (enSembl)ENSG00000156218
Phylogenetic Trees/Animal Genes : TreeFamADAMTSL3
Homologs : HomoloGeneADAMTSL3
Homology/Alignments : Family Browser (UCSC)ADAMTSL3
Gene fusions - Rearrangements
Fusion : MitelmanMAP2K5/ADAMTSL3 [15q23/15q25.2]  
Fusion : MitelmanMCCC1/ADAMTSL3 [3q27.1/15q25.2]  
Fusion : MitelmanNEDD4/ADAMTSL3 [15q21.3/15q25.2]  
Fusion : QuiverADAMTSL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADAMTSL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADAMTSL3
dbVarADAMTSL3
ClinVarADAMTSL3
MonarchADAMTSL3
1000_GenomesADAMTSL3 
Exome Variant ServerADAMTSL3
GNOMAD BrowserENSG00000156218
Varsome BrowserADAMTSL3
ACMGADAMTSL3 variants
VarityP82987
Genomic Variants (DGV)ADAMTSL3 [DGVbeta]
DECIPHERADAMTSL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADAMTSL3 
Mutations
ICGC Data PortalADAMTSL3 
TCGA Data PortalADAMTSL3 
Broad Tumor PortalADAMTSL3
OASIS PortalADAMTSL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADAMTSL3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DADAMTSL3
Mutations and Diseases : HGMDADAMTSL3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaADAMTSL3
DgiDB (Drug Gene Interaction Database)ADAMTSL3
DoCM (Curated mutations)ADAMTSL3
CIViC (Clinical Interpretations of Variants in Cancer)ADAMTSL3
Cancer3DADAMTSL3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609199   
Orphanet
DisGeNETADAMTSL3
MedgenADAMTSL3
Genetic Testing Registry ADAMTSL3
NextProtP82987 [Medical]
GENETestsADAMTSL3
Target ValidationADAMTSL3
Huge Navigator ADAMTSL3 [HugePedia]
ClinGenADAMTSL3
Clinical trials, drugs, therapy
MyCancerGenomeADAMTSL3
Protein Interactions : CTDADAMTSL3
Pharm GKB GenePA134934525
PharosP82987
Clinical trialADAMTSL3
Miscellaneous
canSAR (ICR)ADAMTSL3
HarmonizomeADAMTSL3
DataMed IndexADAMTSL3
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXADAMTSL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:58:30 CEST 2021

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