Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ADAMTSL3 (ADAMTS like 3)

Identity

Alias_symbol (synonym)KIAA1233
punctin-2
Other aliasADAMTSL-3
HGNC (Hugo) ADAMTSL3
LocusID (NCBI) 57188
Atlas_Id 47149
Location 15q25.2  [Link to chromosome band 15q25]
Location_base_pair Starts at 83654086 and ends at 84039841 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADAMTSL3 (15q25.2) / LYPLA1 (8q11.23)MAP2K5 (15q23) / ADAMTSL3 (15q25.2)MCCC1 (3q27.1) / ADAMTSL3 (15q25.2)
NEDD4 (15q21.3) / ADAMTSL3 (15q25.2)MAP2K5 15q23 / ADAMTSL3 15q25.2MCCC1 3q27.1 / ADAMTSL3 15q25.2
NEDD4 15q21.3 / ADAMTSL3 15q25.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADAMTSL3   14633
Cards
Entrez_Gene (NCBI)ADAMTSL3  57188  ADAMTS like 3
AliasesADAMTSL-3
GeneCards (Weizmann)ADAMTSL3
Ensembl hg19 (Hinxton)ENSG00000156218 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156218 [Gene_View]  chr15:83654086-84039841 [Contig_View]  ADAMTSL3 [Vega]
ICGC DataPortalENSG00000156218
TCGA cBioPortalADAMTSL3
AceView (NCBI)ADAMTSL3
Genatlas (Paris)ADAMTSL3
WikiGenes57188
SOURCE (Princeton)ADAMTSL3
Genetics Home Reference (NIH)ADAMTSL3
Genomic and cartography
GoldenPath hg38 (UCSC)ADAMTSL3  -     chr15:83654086-84039841 +  15q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADAMTSL3  -     15q25.2   [Description]    (hg19-Feb_2009)
EnsemblADAMTSL3 - 15q25.2 [CytoView hg19]  ADAMTSL3 - 15q25.2 [CytoView hg38]
Mapping of homologs : NCBIADAMTSL3 [Mapview hg19]  ADAMTSL3 [Mapview hg38]
OMIM609199   
Gene and transcription
Genbank (Entrez)AB033059 AF237652 AK092324 AK308845 AL109723
RefSeq transcript (Entrez)NM_001301110 NM_207517
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADAMTSL3
Cluster EST : UnigeneHs.459162 [ NCBI ]
CGAP (NCI)Hs.459162
Alternative Splicing GalleryENSG00000156218
Gene ExpressionADAMTSL3 [ NCBI-GEO ]   ADAMTSL3 [ EBI - ARRAY_EXPRESS ]   ADAMTSL3 [ SEEK ]   ADAMTSL3 [ MEM ]
Gene Expression Viewer (FireBrowse)ADAMTSL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57188
GTEX Portal (Tissue expression)ADAMTSL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP82987   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP82987  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP82987
Splice isoforms : SwissVarP82987
PhosPhoSitePlusP82987
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    PLAC (PS50900)    TSP1 (PS50092)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Peptidase_M12B_ADAM-TS    PLAC    TSP1_rpt   
Domain families : Pfam (Sanger)I-set (PF07679)    PLAC (PF08686)    TSP_1 (PF00090)   
Domain families : Pfam (NCBI)pfam07679    pfam08686    pfam00090   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  TSP1 (SM00209)  
Conserved Domain (NCBI)ADAMTSL3
DMDM Disease mutations57188
Blocks (Seattle)ADAMTSL3
SuperfamilyP82987
Human Protein AtlasENSG00000156218
Peptide AtlasP82987
HPRD12426
IPIIPI00410588   IPI00788778   
Protein Interaction databases
DIP (DOE-UCLA)P82987
IntAct (EBI)P82987
FunCoupENSG00000156218
BioGRIDADAMTSL3
STRING (EMBL)ADAMTSL3
ZODIACADAMTSL3
Ontologies - Pathways
QuickGOP82987
Ontology : AmiGOprotein binding  proteinaceous extracellular matrix  proteolysis  metallopeptidase activity  zinc ion binding  intracellular membrane-bounded organelle  
Ontology : EGO-EBIprotein binding  proteinaceous extracellular matrix  proteolysis  metallopeptidase activity  zinc ion binding  intracellular membrane-bounded organelle  
NDEx NetworkADAMTSL3
Atlas of Cancer Signalling NetworkADAMTSL3
Wikipedia pathwaysADAMTSL3
Orthology - Evolution
OrthoDB57188
GeneTree (enSembl)ENSG00000156218
Phylogenetic Trees/Animal Genes : TreeFamADAMTSL3
HOVERGENP82987
HOGENOMP82987
Homologs : HomoloGeneADAMTSL3
Homology/Alignments : Family Browser (UCSC)ADAMTSL3
Gene fusions - Rearrangements
Fusion : MitelmanMAP2K5/ADAMTSL3 [15q23/15q25.2]  [t(15;15)(q23;q25)]  
Fusion : MitelmanMCCC1/ADAMTSL3 [3q27.1/15q25.2]  [t(3;15)(q27;q25)]  
Fusion : MitelmanNEDD4/ADAMTSL3 [15q21.3/15q25.2]  [t(15;15)(q21;q25)]  
Fusion: TCGAMAP2K5 15q23 ADAMTSL3 15q25.2 BRCA
Fusion: TCGAMCCC1 3q27.1 ADAMTSL3 15q25.2 LUSC
Fusion: TCGANEDD4 15q21.3 ADAMTSL3 15q25.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADAMTSL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADAMTSL3
dbVarADAMTSL3
ClinVarADAMTSL3
1000_GenomesADAMTSL3 
Exome Variant ServerADAMTSL3
ExAC (Exome Aggregation Consortium)ADAMTSL3 (select the gene name)
Genetic variants : HAPMAP57188
Genomic Variants (DGV)ADAMTSL3 [DGVbeta]
DECIPHERADAMTSL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADAMTSL3 
Mutations
ICGC Data PortalADAMTSL3 
TCGA Data PortalADAMTSL3 
Broad Tumor PortalADAMTSL3
OASIS PortalADAMTSL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADAMTSL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADAMTSL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADAMTSL3
DgiDB (Drug Gene Interaction Database)ADAMTSL3
DoCM (Curated mutations)ADAMTSL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADAMTSL3 (select a term)
intoGenADAMTSL3
Cancer3DADAMTSL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609199   
Orphanet
MedgenADAMTSL3
Genetic Testing Registry ADAMTSL3
NextProtP82987 [Medical]
TSGene57188
GENETestsADAMTSL3
Target ValidationADAMTSL3
Huge Navigator ADAMTSL3 [HugePedia]
snp3D : Map Gene to Disease57188
BioCentury BCIQADAMTSL3
ClinGenADAMTSL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57188
Chemical/Pharm GKB GenePA134934525
Clinical trialADAMTSL3
Miscellaneous
canSAR (ICR)ADAMTSL3 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADAMTSL3
EVEXADAMTSL3
GoPubMedADAMTSL3
iHOPADAMTSL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:22:48 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.