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ADAMTSL5 (ADAMTS like 5)

Identity

Alias_namesTHSD6
thrombospondin, type I, domain containing 6
Other alias
HGNC (Hugo) ADAMTSL5
LocusID (NCBI) 339366
Atlas_Id 60147
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1505018 and ends at 1513189 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADAMTSL5   27912
Cards
Entrez_Gene (NCBI)ADAMTSL5  339366  ADAMTS like 5
AliasesTHSD6
GeneCards (Weizmann)ADAMTSL5
Ensembl hg19 (Hinxton)ENSG00000185761 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185761 [Gene_View]  chr19:1505018-1513189 [Contig_View]  ADAMTSL5 [Vega]
ICGC DataPortalENSG00000185761
TCGA cBioPortalADAMTSL5
AceView (NCBI)ADAMTSL5
Genatlas (Paris)ADAMTSL5
WikiGenes339366
SOURCE (Princeton)ADAMTSL5
Genetics Home Reference (NIH)ADAMTSL5
Genomic and cartography
GoldenPath hg38 (UCSC)ADAMTSL5  -     chr19:1505018-1513189 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADAMTSL5  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblADAMTSL5 - 19p13.3 [CytoView hg19]  ADAMTSL5 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIADAMTSL5 [Mapview hg19]  ADAMTSL5 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK131571 AK302020 BC040620 BC119796 BC139833
RefSeq transcript (Entrez)NM_213604
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADAMTSL5
Cluster EST : UnigeneHs.371674 [ NCBI ]
CGAP (NCI)Hs.371674
Alternative Splicing GalleryENSG00000185761
Gene ExpressionADAMTSL5 [ NCBI-GEO ]   ADAMTSL5 [ EBI - ARRAY_EXPRESS ]   ADAMTSL5 [ SEEK ]   ADAMTSL5 [ MEM ]
Gene Expression Viewer (FireBrowse)ADAMTSL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339366
GTEX Portal (Tissue expression)ADAMTSL5
Human Protein AtlasENSG00000185761-ADAMTSL5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZMM2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZMM2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZMM2
Splice isoforms : SwissVarQ6ZMM2
PhosPhoSitePlusQ6ZMM2
Domaine pattern : Prosite (Expaxy)NTR (PS50189)    TSP1 (PS50092)   
Domains : Interpro (EBI)ADAM_spacer1    Netrin_domain    Netrin_module_non-TIMP    Peptidase_M12B_ADAM-TS    TIMP-like_OB-fold    TSP1_rpt   
Domain families : Pfam (Sanger)ADAM_spacer1 (PF05986)    NTR (PF01759)    TSP_1 (PF00090)   
Domain families : Pfam (NCBI)pfam05986    pfam01759    pfam00090   
Domain families : Smart (EMBL)C345C (SM00643)  TSP1 (SM00209)  
Conserved Domain (NCBI)ADAMTSL5
DMDM Disease mutations339366
Blocks (Seattle)ADAMTSL5
SuperfamilyQ6ZMM2
Human Protein Atlas [tissue]ENSG00000185761-ADAMTSL5 [tissue]
Peptide AtlasQ6ZMM2
HPRD15504
IPIIPI00940001   IPI00412698   IPI00785059   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZMM2
IntAct (EBI)Q6ZMM2
FunCoupENSG00000185761
BioGRIDADAMTSL5
STRING (EMBL)ADAMTSL5
ZODIACADAMTSL5
Ontologies - Pathways
QuickGOQ6ZMM2
Ontology : AmiGOmicrofibril  microfibril  metalloendopeptidase activity  extracellular region  proteinaceous extracellular matrix  proteolysis  heparin binding  zinc ion binding  
Ontology : EGO-EBImicrofibril  microfibril  metalloendopeptidase activity  extracellular region  proteinaceous extracellular matrix  proteolysis  heparin binding  zinc ion binding  
NDEx NetworkADAMTSL5
Atlas of Cancer Signalling NetworkADAMTSL5
Wikipedia pathwaysADAMTSL5
Orthology - Evolution
OrthoDB339366
GeneTree (enSembl)ENSG00000185761
Phylogenetic Trees/Animal Genes : TreeFamADAMTSL5
HOVERGENQ6ZMM2
HOGENOMQ6ZMM2
Homologs : HomoloGeneADAMTSL5
Homology/Alignments : Family Browser (UCSC)ADAMTSL5
Gene fusions - Rearrangements
Tumor Fusion PortalADAMTSL5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADAMTSL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADAMTSL5
dbVarADAMTSL5
ClinVarADAMTSL5
1000_GenomesADAMTSL5 
Exome Variant ServerADAMTSL5
ExAC (Exome Aggregation Consortium)ENSG00000185761
GNOMAD BrowserENSG00000185761
Genetic variants : HAPMAP339366
Genomic Variants (DGV)ADAMTSL5 [DGVbeta]
DECIPHERADAMTSL5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADAMTSL5 
Mutations
ICGC Data PortalADAMTSL5 
TCGA Data PortalADAMTSL5 
Broad Tumor PortalADAMTSL5
OASIS PortalADAMTSL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADAMTSL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADAMTSL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADAMTSL5
DgiDB (Drug Gene Interaction Database)ADAMTSL5
DoCM (Curated mutations)ADAMTSL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADAMTSL5 (select a term)
intoGenADAMTSL5
Cancer3DADAMTSL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETADAMTSL5
MedgenADAMTSL5
Genetic Testing Registry ADAMTSL5
NextProtQ6ZMM2 [Medical]
TSGene339366
GENETestsADAMTSL5
Target ValidationADAMTSL5
Huge Navigator ADAMTSL5 [HugePedia]
snp3D : Map Gene to Disease339366
BioCentury BCIQADAMTSL5
ClinGenADAMTSL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339366
Chemical/Pharm GKB GenePA134867057
Clinical trialADAMTSL5
Miscellaneous
canSAR (ICR)ADAMTSL5 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADAMTSL5
EVEXADAMTSL5
GoPubMedADAMTSL5
iHOPADAMTSL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:38:05 CET 2017

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