Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ADAP1 (ArfGAP with dual PH domains 1)

Identity

Other namesCENTA1
GCS1L
p42IP4
HGNC (Hugo) ADAP1
LocusID (NCBI) 11033
Location 7p22.3
Location_base_pair Starts at 937537 and ends at 994289 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADAP1   16486
Entrez_Gene (NCBI)ADAP1  11033  ArfGAP with dual PH domains 1
Cards
GeneCards (Weizmann)ADAP1
Ensembl (Hinxton)ENSG00000105963 [Gene_View]  chr7:937537-994289 [Contig_View]  ADAP1 [Vega]
AceView (NCBI)ADAP1
Genatlas (Paris)ADAP1
SOURCE (Stanford)NM_006869
Genomic and cartography
GoldenPath (UCSC)ADAP1  -  7p22.3   chr7:937537-994289 -  7p22.3   [Description]    (hg19-Feb_2009)
EnsemblADAP1 - 7p22.3 [CytoView]
Mapping of homologs : NCBIADAP1 [Mapview]
OMIM608114   
Gene and transcription
Genbank (Entrez)AB097049 AF082324 AI910700 AJ006422 AK092471
RefSeq transcript (SRS)NM_006869
RefSeq transcript (Entrez)NM_006869
RefSeq genomic (SRS)AC_000068 AC_000139 NC_000007 NC_018918 NT_007819 NT_079592 NW_001838998 NW_004078029
RefSeq genomic (Entrez)AC_000068 AC_000139 NC_000007 NC_018918 NT_007819 NT_079592 NW_001838998 NW_004078029
Consensus coding sequences : CCDS (NCBI)ADAP1
Cluster EST : UnigeneHs.602573 [ SRS ] Hs.602573 [ NCBI ]
CGAP (NCI)Hs.602573
Alternative Splicing : Fast-db (Paris)GSHG0027948
Alternative Splicing GalleryENSG00000105963
Gene ExpressionADAP1 [ NCBI-GEO ]   ADAP1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75689 (SRS) O75689 (Uniprot)
NextProtO75689
With graphics : InterProO75689
Splice isoforms : SwissVarO75689(Swissvar)
Domaine pattern : Prosite (SRS)ARFGAP (PS50115)    PH_DOMAIN (PS50003)   
Domaine pattern : Prosite (Expaxy)ARFGAP (PS50115)    PH_DOMAIN (PS50003)   
Domains : Interpro (SRS)ArfGAP    PH_like_dom    Pleckstrin_homology   
Domains : Interpro (EBI)ArfGAP    PH_like_dom    Pleckstrin_homology   
Related proteins : CluSTrO75689
Domain families : Pfam (SRS)ArfGap (PF01412)    PH (PF00169)   
Domain families : Pfam (Sanger)ArfGap (PF01412)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01412    pfam00169   
Domain families : Smart (EMBL)ArfGap (SM00105)  PH (SM00233)  
DMDM11033
Blocks (Seattle)O75689
PDB (SRS)3FEH    3FM8    3LJU    3MDB   
PDB (PDBSum)3FEH    3FM8    3LJU    3MDB   
PDB (IMB)3FEH    3FM8    3LJU    3MDB   
PDB (RSDB)3FEH    3FM8    3LJU    3MDB   
Human Protein AtlasENSG00000105963
HPRD09733
IPIIPI00009992   IPI00892713   IPI01011441   IPI00893823   IPI00941118   IPI00893970   IPI00893486   IPI00893187   IPI00894327   
Protein Interaction databases
DIP (DOE-UCLA)O75689
IntAct (EBI)O75689
FunCoupENSG00000105963
REACTOMEADAP1
Protein Interaction Database11033
BioGRIDADAP1
InParanoidO75689
Interologous Interaction database O75689
IntegromeDBADAP1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ADAP1
SNP (GeneSNP Utah)ADAP1
SNP : HGBaseADAP1
Genetic variants : HAPMAPADAP1
Somatic Mutations in Cancer : COSMICADAP1 
CONAN: Copy Number AnalysisADAP1 
Mutations and Diseases : HGMDADAP1
OMIM608114   
GENETests608114   
Disease Genetic AssociationADAP1
Huge Navigator ADAP1 [HugePedia]  ADAP1 [HugeCancerGEM]
Genomic VariantsADAP1  ADAP1 [DGVbeta]
snp3D : Map Gene to Disease11033
General knowledge
Homologs : HomoloGeneADAP1
Homology/Alignments : Family Browser (UCSC)ADAP1
Phylogenetic Trees/Animal Genes : TreeFamADAP1
Chemical/Protein Interactions : CTD11033
Chemical/Pharm GKB GenePA26404
Clinical trialADAP1
Cancer Resource (Charite)ENSG00000105963
Ontology : AmiGOprotein binding  phospholipid binding  nucleus  cytoplasm  plasma membrane  cell surface receptor signaling pathway  ARF GTPase activator activity  zinc ion binding  regulation of ARF GTPase activity  regulation of GTPase activity  inositol 1,3,4,5 tetrakisphosphate binding  metal ion binding  
Ontology : EGO-EBIprotein binding  phospholipid binding  nucleus  cytoplasm  plasma membrane  cell surface receptor signaling pathway  ARF GTPase activator activity  zinc ion binding  regulation of ARF GTPase activity  regulation of GTPase activity  inositol 1,3,4,5 tetrakisphosphate binding  metal ion binding  
Other databases
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
PubGeneADAP1
iHOPADAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:39:40 CEST 2013

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.