ADAP2 (ArfGAP with dual PH domains 2)

2014-11-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
CENTA2,HSA272195,cent-b
FUSION GENES

Other Information

Locus ID:

NCBI: 55803
MIM: 608635
HGNC: 16487
Ensembl: ENSG00000184060

Variants:

dbSNP: 55803
ClinVar: 55803
TCGA: ENSG00000184060
COSMIC: ADAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184060ENST00000330889Q9NPF8
ENSG00000184060ENST00000580525Q2V6Q1
ENSG00000184060ENST00000580526J3KT70
ENSG00000184060ENST00000581285J3QRD3
ENSG00000184060ENST00000581548K7ENT1
ENSG00000184060ENST00000584828J3QLP8
ENSG00000184060ENST00000584989J3KST1
ENSG00000184060ENST00000585130J3QRA6

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
192660772009Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.48
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.19
263726452015ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry.12
232852092012Centaurin-α₂ interacts with β-tubulin and stabilizes microtubules.6
146905212004Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins.5
279567052017ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production.4
192917642009RNF135 mutations are not present in patients with Sotos syndrome-like features.2

Citation

Dessen P

ADAP2 (ArfGAP with dual PH domains 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60148/adap2