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ADARB2 (adenosine deaminase, RNA-specific, B2 (non-functional))

Identity

Alias_namesadenosine deaminase, RNA-specific, B2 (RED2 homolog rat)
adenosine deaminase, RNA-specific, B2
adenosine deaminase, RNA-specific, B2 (non-functional)
Alias_symbol (synonym)RED2
hRED2
ADAR3
Other alias
HGNC (Hugo) ADARB2
LocusID (NCBI) 105
Atlas_Id 60149
Location 10p15.3  [Link to chromosome band 10p15]
Location_base_pair Starts at 1223253 and ends at 1779670 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADARB2 (10p15.3) / PFKP (10p15.2)ADARB2 (10p15.3) / PTPN7 (1q32.1)NUMA1 (11q13.4) / ADARB2 (10p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADARB2   227
Cards
Entrez_Gene (NCBI)ADARB2  105  adenosine deaminase, RNA-specific, B2 (non-functional)
AliasesADAR3; RED2
GeneCards (Weizmann)ADARB2
Ensembl hg19 (Hinxton)ENSG00000185736 [Gene_View]  chr10:1223253-1779670 [Contig_View]  ADARB2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000185736 [Gene_View]  chr10:1223253-1779670 [Contig_View]  ADARB2 [Vega]
ICGC DataPortalENSG00000185736
TCGA cBioPortalADARB2
AceView (NCBI)ADARB2
Genatlas (Paris)ADARB2
WikiGenes105
SOURCE (Princeton)ADARB2
Genetics Home Reference (NIH)ADARB2
Genomic and cartography
GoldenPath hg19 (UCSC)ADARB2  -     chr10:1223253-1779670 -  10p15.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ADARB2  -     10p15.3   [Description]    (hg38-Dec_2013)
EnsemblADARB2 - 10p15.3 [CytoView hg19]  ADARB2 - 10p15.3 [CytoView hg38]
Mapping of homologs : NCBIADARB2 [Mapview hg19]  ADARB2 [Mapview hg38]
OMIM602065   
Gene and transcription
Genbank (Entrez)AF034837 AI695657 AK055107 AK057763 AK094294
RefSeq transcript (Entrez)NM_018702
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_008705 NW_004929370
Consensus coding sequences : CCDS (NCBI)ADARB2
Cluster EST : UnigeneHs.586663 [ NCBI ]
CGAP (NCI)Hs.586663
Alternative Splicing GalleryENSG00000185736
Gene ExpressionADARB2 [ NCBI-GEO ]   ADARB2 [ EBI - ARRAY_EXPRESS ]   ADARB2 [ SEEK ]   ADARB2 [ MEM ]
Gene Expression Viewer (FireBrowse)ADARB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)105
GTEX Portal (Tissue expression)ADARB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS39   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS39  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS39
Splice isoforms : SwissVarQ9NS39
Catalytic activity : Enzyme3.5.-.- [ Enzyme-Expasy ]   3.5.-.-3.5.-.- [ IntEnz-EBI ]   3.5.-.- [ BRENDA ]   3.5.-.- [ KEGG ]   
PhosPhoSitePlusQ9NS39
Domaine pattern : Prosite (Expaxy)A_DEAMIN_EDITASE (PS50141)    DS_RBD (PS50137)   
Domains : Interpro (EBI)A_deamin    dsRNA-bd_dom   
Domain families : Pfam (Sanger)A_deamin (PF02137)    dsrm (PF00035)   
Domain families : Pfam (NCBI)pfam02137    pfam00035   
Domain families : Smart (EMBL)ADEAMc (SM00552)  DSRM (SM00358)  
Conserved Domain (NCBI)ADARB2
DMDM Disease mutations105
Blocks (Seattle)ADARB2
SuperfamilyQ9NS39
Human Protein AtlasENSG00000185736
Peptide AtlasQ9NS39
HPRD09070
IPIIPI00033017   IPI00848069   IPI00395952   IPI00640752   IPI00644884   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS39
IntAct (EBI)Q9NS39
FunCoupENSG00000185736
BioGRIDADARB2
STRING (EMBL)ADARB2
ZODIACADARB2
Ontologies - Pathways
QuickGOQ9NS39
Ontology : AmiGOdouble-stranded RNA binding  single-stranded RNA binding  adenosine deaminase activity  nucleus  mRNA processing  poly(A) RNA binding  metal ion binding  
Ontology : EGO-EBIdouble-stranded RNA binding  single-stranded RNA binding  adenosine deaminase activity  nucleus  mRNA processing  poly(A) RNA binding  metal ion binding  
NDEx NetworkADARB2
Atlas of Cancer Signalling NetworkADARB2
Wikipedia pathwaysADARB2
Orthology - Evolution
OrthoDB105
GeneTree (enSembl)ENSG00000185736
Phylogenetic Trees/Animal Genes : TreeFamADARB2
HOVERGENQ9NS39
HOGENOMQ9NS39
Homologs : HomoloGeneADARB2
Homology/Alignments : Family Browser (UCSC)ADARB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADARB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADARB2
dbVarADARB2
ClinVarADARB2
1000_GenomesADARB2 
Exome Variant ServerADARB2
ExAC (Exome Aggregation Consortium)ADARB2 (select the gene name)
Genetic variants : HAPMAP105
Genomic Variants (DGV)ADARB2 [DGVbeta]
DECIPHER (Syndromes)10:1223253-1779670  ENSG00000185736
CONAN: Copy Number AnalysisADARB2 
Mutations
ICGC Data PortalADARB2 
TCGA Data PortalADARB2 
Broad Tumor PortalADARB2
OASIS PortalADARB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADARB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADARB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADARB2
DgiDB (Drug Gene Interaction Database)ADARB2
DoCM (Curated mutations)ADARB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADARB2 (select a term)
intoGenADARB2
Cancer3DADARB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602065   
Orphanet
MedgenADARB2
Genetic Testing Registry ADARB2
NextProtQ9NS39 [Medical]
TSGene105
GENETestsADARB2
Huge Navigator ADARB2 [HugePedia]
snp3D : Map Gene to Disease105
BioCentury BCIQADARB2
ClinGenADARB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD105
Chemical/Pharm GKB GenePA24557
Clinical trialADARB2
Miscellaneous
canSAR (ICR)ADARB2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADARB2
EVEXADARB2
GoPubMedADARB2
iHOPADARB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:53:42 CET 2017

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