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ADAT2 (adenosine deaminase, tRNA specific 2)

Identity

Alias_namesDEADC1
deaminase domain containing 1
adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae)
Alias_symbol (synonym)dJ20N2.1
TAD2
Other aliasdJ20N2
HGNC (Hugo) ADAT2
LocusID (NCBI) 134637
Atlas_Id 56182
Location 6q24.2  [Link to chromosome band 6q24]
Location_base_pair Starts at 143422832 and ends at 143450704 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAT2 (6q24.2) / COBLL1 (2q24.3)LOC144571 () / ADAT2 (6q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADAT2   21172
Cards
Entrez_Gene (NCBI)ADAT2  134637  adenosine deaminase, tRNA specific 2
AliasesDEADC1; TAD2; dJ20N2; dJ20N2.1
GeneCards (Weizmann)ADAT2
Ensembl hg19 (Hinxton)ENSG00000189007 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189007 [Gene_View]  ENSG00000189007 [Sequence]  chr6:143422832-143450704 [Contig_View]  ADAT2 [Vega]
ICGC DataPortalENSG00000189007
TCGA cBioPortalADAT2
AceView (NCBI)ADAT2
Genatlas (Paris)ADAT2
WikiGenes134637
SOURCE (Princeton)ADAT2
Genetics Home Reference (NIH)ADAT2
Genomic and cartography
GoldenPath hg38 (UCSC)ADAT2  -     chr6:143422832-143450704 -  6q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADAT2  -     6q24.2   [Description]    (hg19-Feb_2009)
EnsemblADAT2 - 6q24.2 [CytoView hg19]  ADAT2 - 6q24.2 [CytoView hg38]
Mapping of homologs : NCBIADAT2 [Mapview hg19]  ADAT2 [Mapview hg38]
OMIM615388   
Gene and transcription
Genbank (Entrez)AK126201 BC037955 BM680217 BX538182 DA100320
RefSeq transcript (Entrez)NM_001286259 NM_182503
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADAT2
Cluster EST : UnigeneHs.709561 [ NCBI ]
CGAP (NCI)Hs.709561
Alternative Splicing GalleryENSG00000189007
Gene ExpressionADAT2 [ NCBI-GEO ]   ADAT2 [ EBI - ARRAY_EXPRESS ]   ADAT2 [ SEEK ]   ADAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)ADAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)134637
GTEX Portal (Tissue expression)ADAT2
Human Protein AtlasENSG00000189007-ADAT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z6V5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z6V5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z6V5
Splice isoforms : SwissVarQ7Z6V5
PhosPhoSitePlusQ7Z6V5
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    CMP_dCMP_dom    Cytidine_deaminase-like    tRNA_aden_deaminase   
Domain families : Pfam (Sanger)MafB19-deam (PF14437)   
Domain families : Pfam (NCBI)pfam14437   
Conserved Domain (NCBI)ADAT2
DMDM Disease mutations134637
Blocks (Seattle)ADAT2
PDB (SRS)3DH1   
PDB (PDBSum)3DH1   
PDB (IMB)3DH1   
PDB (RSDB)3DH1   
Structural Biology KnowledgeBase3DH1   
SCOP (Structural Classification of Proteins)3DH1   
CATH (Classification of proteins structures)3DH1   
SuperfamilyQ7Z6V5
Human Protein Atlas [tissue]ENSG00000189007-ADAT2 [tissue]
Peptide AtlasQ7Z6V5
IPIIPI00217631   IPI00845439   IPI00385463   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z6V5
IntAct (EBI)Q7Z6V5
FunCoupENSG00000189007
BioGRIDADAT2
STRING (EMBL)ADAT2
ZODIACADAT2
Ontologies - Pathways
QuickGOQ7Z6V5
Ontology : AmiGOtRNA wobble adenosine to inosine editing  tRNA wobble adenosine to inosine editing  protein binding  nucleoplasm  tRNA modification  zinc ion binding  tRNA-specific adenosine-34 deaminase activity  tRNA-specific adenosine-34 deaminase complex  
Ontology : EGO-EBItRNA wobble adenosine to inosine editing  tRNA wobble adenosine to inosine editing  protein binding  nucleoplasm  tRNA modification  zinc ion binding  tRNA-specific adenosine-34 deaminase activity  tRNA-specific adenosine-34 deaminase complex  
NDEx NetworkADAT2
Atlas of Cancer Signalling NetworkADAT2
Wikipedia pathwaysADAT2
Orthology - Evolution
OrthoDB134637
GeneTree (enSembl)ENSG00000189007
Phylogenetic Trees/Animal Genes : TreeFamADAT2
HOVERGENQ7Z6V5
HOGENOMQ7Z6V5
Homologs : HomoloGeneADAT2
Homology/Alignments : Family Browser (UCSC)ADAT2
Gene fusions - Rearrangements
Fusion : QuiverADAT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADAT2
dbVarADAT2
ClinVarADAT2
1000_GenomesADAT2 
Exome Variant ServerADAT2
ExAC (Exome Aggregation Consortium)ENSG00000189007
GNOMAD BrowserENSG00000189007
Varsome BrowserADAT2
Genetic variants : HAPMAP134637
Genomic Variants (DGV)ADAT2 [DGVbeta]
DECIPHERADAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADAT2 
Mutations
ICGC Data PortalADAT2 
TCGA Data PortalADAT2 
Broad Tumor PortalADAT2
OASIS PortalADAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADAT2
DgiDB (Drug Gene Interaction Database)ADAT2
DoCM (Curated mutations)ADAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADAT2 (select a term)
intoGenADAT2
Cancer3DADAT2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615388   
Orphanet
DisGeNETADAT2
MedgenADAT2
Genetic Testing Registry ADAT2
NextProtQ7Z6V5 [Medical]
TSGene134637
GENETestsADAT2
Target ValidationADAT2
Huge Navigator ADAT2 [HugePedia]
snp3D : Map Gene to Disease134637
BioCentury BCIQADAT2
ClinGenADAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD134637
Chemical/Pharm GKB GenePA162375592
Clinical trialADAT2
Miscellaneous
canSAR (ICR)ADAT2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADAT2
EVEXADAT2
GoPubMedADAT2
iHOPADAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:07:51 CEST 2018

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