Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ADCY10 (adenylate cyclase 10 (soluble))

Identity

Alias_symbol (synonym)SAC
Sacy
SACI
HCA2
RP1-313L4.2
Other aliasHEL-S-7a
hsAC
HGNC (Hugo) ADCY10
LocusID (NCBI) 55811
Atlas_Id 53251
Location 1q24.2  [Link to chromosome band 1q24]
Location_base_pair Starts at 167778625 and ends at 167883464 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ESRRG (1q41) / ADCY10 (1q24.2)ESRRG 1q41 / ADCY10 1q24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADCY10   21285
Cards
Entrez_Gene (NCBI)ADCY10  55811  adenylate cyclase 10 (soluble)
AliasesHCA2; HEL-S-7a; SAC; SACI; 
Sacy; hsAC
GeneCards (Weizmann)ADCY10
Ensembl hg19 (Hinxton)ENSG00000143199 [Gene_View]  chr1:167778625-167883464 [Contig_View]  ADCY10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143199 [Gene_View]  chr1:167778625-167883464 [Contig_View]  ADCY10 [Vega]
ICGC DataPortalENSG00000143199
TCGA cBioPortalADCY10
AceView (NCBI)ADCY10
Genatlas (Paris)ADCY10
WikiGenes55811
SOURCE (Princeton)ADCY10
Genetics Home Reference (NIH)ADCY10
Genomic and cartography
GoldenPath hg19 (UCSC)ADCY10  -     chr1:167778625-167883464 -  1q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ADCY10  -     1q24.2   [Description]    (hg38-Dec_2013)
EnsemblADCY10 - 1q24.2 [CytoView hg19]  ADCY10 - 1q24.2 [CytoView hg38]
Mapping of homologs : NCBIADCY10 [Mapview hg19]  ADCY10 [Mapview hg38]
OMIM143870   605205   
Gene and transcription
Genbank (Entrez)AF176813 AF271058 AF299350 AF331033 AK302884
RefSeq transcript (Entrez)NM_001167749 NM_001297772 NM_018417
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_016139 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)ADCY10
Cluster EST : UnigeneHs.320892 [ NCBI ]
CGAP (NCI)Hs.320892
Alternative Splicing GalleryENSG00000143199
Gene ExpressionADCY10 [ NCBI-GEO ]   ADCY10 [ EBI - ARRAY_EXPRESS ]   ADCY10 [ SEEK ]   ADCY10 [ MEM ]
Gene Expression Viewer (FireBrowse)ADCY10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55811
GTEX Portal (Tissue expression)ADCY10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PN6
Splice isoforms : SwissVarQ96PN6
PhosPhoSitePlusQ96PN6
Domaine pattern : Prosite (Expaxy)GUANYLATE_CYCLASE_2 (PS50125)   
Domains : Interpro (EBI)A/G_cyclase    Adenylate_cylcase_typ10    Nucleotide_cyclase    P-loop_NTPase    TPR-like_helical_dom   
Domain families : Pfam (Sanger)Guanylate_cyc (PF00211)   
Domain families : Pfam (NCBI)pfam00211   
Domain families : Smart (EMBL)CYCc (SM00044)  
Conserved Domain (NCBI)ADCY10
DMDM Disease mutations55811
Blocks (Seattle)ADCY10
PDB (SRS)4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
PDB (PDBSum)4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
PDB (IMB)4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
PDB (RSDB)4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
Structural Biology KnowledgeBase4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
SCOP (Structural Classification of Proteins)4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
CATH (Classification of proteins structures)4CLF    4CLK    4CLL    4CLP    4CLS    4CLT    4CLU    4CLW    4CLY    4CLZ    4CM0    4CM2    4OYA    4OYB    4OYI    4OYM    4OYO    4OYP    4OYW    4OYX    4OYZ    4OZ2    4OZ3    4UST    4USU    4USV    4USW   
SuperfamilyQ96PN6
Human Protein AtlasENSG00000143199
Peptide AtlasQ96PN6
HPRD05549
IPIIPI00742726   IPI00641214   IPI00514661   
Protein Interaction databases
DIP (DOE-UCLA)Q96PN6
IntAct (EBI)Q96PN6
FunCoupENSG00000143199
BioGRIDADCY10
STRING (EMBL)ADCY10
ZODIACADCY10
Ontologies - Pathways
QuickGOQ96PN6
Ontology : AmiGOmagnesium ion binding  epithelial cilium movement  adenylate cyclase activity  adenylate cyclase activity  ATP binding  nucleus  cytoplasm  mitochondrion  cytosol  plasma membrane  cAMP biosynthetic process  cAMP biosynthetic process  spermatogenesis  microtubule cytoskeleton  manganese ion binding  axon  dendrite  growth cone  motile cilium  intracellular signal transduction  neuronal cell body  positive regulation of apoptotic process  apical part of cell  basal part of cell  perinuclear region of cytoplasm  ATPase binding  cellular response to inorganic substance  bicarbonate binding  
Ontology : EGO-EBImagnesium ion binding  epithelial cilium movement  adenylate cyclase activity  adenylate cyclase activity  ATP binding  nucleus  cytoplasm  mitochondrion  cytosol  plasma membrane  cAMP biosynthetic process  cAMP biosynthetic process  spermatogenesis  microtubule cytoskeleton  manganese ion binding  axon  dendrite  growth cone  motile cilium  intracellular signal transduction  neuronal cell body  positive regulation of apoptotic process  apical part of cell  basal part of cell  perinuclear region of cytoplasm  ATPase binding  cellular response to inorganic substance  bicarbonate binding  
Pathways : KEGGPurine metabolism    Circadian entrainment   
NDEx NetworkADCY10
Atlas of Cancer Signalling NetworkADCY10
Wikipedia pathwaysADCY10
Orthology - Evolution
OrthoDB55811
GeneTree (enSembl)ENSG00000143199
Phylogenetic Trees/Animal Genes : TreeFamADCY10
HOVERGENQ96PN6
HOGENOMQ96PN6
Homologs : HomoloGeneADCY10
Homology/Alignments : Family Browser (UCSC)ADCY10
Gene fusions - Rearrangements
Fusion : MitelmanESRRG/ADCY10 [1q41/1q24.2]  [t(1;1)(q24;q41)]  
Fusion: TCGAESRRG 1q41 ADCY10 1q24.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADCY10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADCY10
dbVarADCY10
ClinVarADCY10
1000_GenomesADCY10 
Exome Variant ServerADCY10
ExAC (Exome Aggregation Consortium)ADCY10 (select the gene name)
Genetic variants : HAPMAP55811
Genomic Variants (DGV)ADCY10 [DGVbeta]
DECIPHER (Syndromes)1:167778625-167883464  ENSG00000143199
CONAN: Copy Number AnalysisADCY10 
Mutations
ICGC Data PortalADCY10 
TCGA Data PortalADCY10 
Broad Tumor PortalADCY10
OASIS PortalADCY10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADCY10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADCY10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADCY10
DgiDB (Drug Gene Interaction Database)ADCY10
DoCM (Curated mutations)ADCY10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADCY10 (select a term)
intoGenADCY10
Cancer3DADCY10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM143870    605205   
Orphanet3625   
MedgenADCY10
Genetic Testing Registry ADCY10
NextProtQ96PN6 [Medical]
TSGene55811
GENETestsADCY10
Huge Navigator ADCY10 [HugePedia]
snp3D : Map Gene to Disease55811
BioCentury BCIQADCY10
ClinGenADCY10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55811
Chemical/Pharm GKB GenePA162375618
Clinical trialADCY10
Miscellaneous
canSAR (ICR)ADCY10 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADCY10
EVEXADCY10
GoPubMedADCY10
iHOPADCY10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:54:57 CET 2017

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