Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ADCY6 (adenylate cyclase 6)

Identity

Other namesAC6
HGNC (Hugo) ADCY6
LocusID (NCBI) 112
Location 12q13.12
Location_base_pair Starts at 49159975 and ends at 49177877 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADCY6   237
Entrez_Gene (NCBI)ADCY6  112  adenylate cyclase 6
Cards
GeneCards (Weizmann)ADCY6
Ensembl (Hinxton)ENSG00000174233 [Gene_View]  chr12:49159975-49177877 [Contig_View]  ADCY6 [Vega]
AceView (NCBI)ADCY6
Genatlas (Paris)ADCY6
SOURCE (Stanford)NM_015270 NM_020983
Genomic and cartography
GoldenPath (UCSC)ADCY6  -  12q13.12   chr12:49159975-49177877 -  12q13.12   [Description]    (hg19-Feb_2009)
EnsemblADCY6 - 12q13.12 [CytoView]
Mapping of homologs : NCBIADCY6 [Mapview]
OMIM600294   
Gene and transcription
Genbank (Entrez)AB007882 AF250226 AK225224 AK294446 BC064923
RefSeq transcript (SRS)NM_015270 NM_020983
RefSeq transcript (Entrez)NM_015270 NM_020983
RefSeq genomic (SRS)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004078075
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004078075
Consensus coding sequences : CCDS (NCBI)ADCY6
Cluster EST : UnigeneHs.694408 [ SRS ] Hs.694408 [ NCBI ]
CGAP (NCI)Hs.694408
Alternative Splicing : Fast-db (Paris)GSHG0007426
Alternative Splicing GalleryENSG00000174233
Gene ExpressionADCY6 [ NCBI-GEO ]   ADCY6 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43306 (SRS) O43306 (Uniprot)
NextProtO43306
With graphics : InterProO43306
Splice isoforms : SwissVarO43306(Swissvar)
Domaine pattern : Prosite (SRS)GUANYLATE_CYCLASE_1 (PS00452)    GUANYLATE_CYCLASE_2 (PS50125)   
Domaine pattern : Prosite (Expaxy)GUANYLATE_CYCLASE_1 (PS00452)    GUANYLATE_CYCLASE_2 (PS50125)   
Domains : Interpro (SRS)A/G_cyclase    A/G_cyclase_CS    Adenylate_cyclase-like   
Domains : Interpro (EBI)A/G_cyclase    A/G_cyclase_CS    Adenylate_cyclase-like   
Related proteins : CluSTrO43306
Domain families : Pfam (SRS)DUF1053 (PF06327)    Guanylate_cyc (PF00211)   
Domain families : Pfam (Sanger)DUF1053 (PF06327)    Guanylate_cyc (PF00211)   
Domain families : Pfam (NCBI)pfam06327    pfam00211   
Domain families : Smart (EMBL)CYCc (SM00044)  
DMDM112
Blocks (Seattle)O43306
Human Protein AtlasENSG00000174233
HPRD02621
IPIIPI00011938   IPI00220444   IPI00910029   IPI01022435   
Protein Interaction databases
DIP (DOE-UCLA)O43306
IntAct (EBI)O43306
FunCoupENSG00000174233
REACTOMEADCY6
Protein Interaction Database112
BioGRIDADCY6
InParanoidO43306
Interologous Interaction database O43306
IntegromeDBADCY6
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ADCY6
SNP (GeneSNP Utah)ADCY6
SNP : HGBaseADCY6
Genetic variants : HAPMAPADCY6
Somatic Mutations in Cancer : COSMICADCY6 
CONAN: Copy Number AnalysisADCY6 
Mutations and Diseases : HGMDADCY6
OMIM600294   
GENETests600294   
Disease Genetic AssociationADCY6
Huge Navigator ADCY6 [HugePedia]  ADCY6 [HugeCancerGEM]
Genomic VariantsADCY6  ADCY6 [DGVbeta]
snp3D : Map Gene to Disease112
General knowledge
Homologs : HomoloGeneADCY6
Homology/Alignments : Family Browser (UCSC)ADCY6
Phylogenetic Trees/Animal Genes : TreeFamADCY6
Catalytic activity : Enzyme4.6.1.1 [ Enzyme-Expasy ]   4.6.1.1 [ Enzyme-SRS ]   4.6.1.1 [ IntEnz-EBI ]   4.6.1.1 [ BRENDA ]   4.6.1.1 [ KEGG ]   
Chemical/Protein Interactions : CTD112
Chemical/Pharm GKB GenePA27
Clinical trialADCY6
Cancer Resource (Charite)ENSG00000174233
Ontology : AmiGOadenylate cyclase activity  receptor binding  protein binding  ATP binding  endosome  plasma membrane  cilium  energy reserve metabolic process  cAMP biosynthetic process  water transport  signal transduction  epidermal growth factor receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  activation of phospholipase C activity  dopamine receptor signaling pathway  synaptic transmission  calcium- and calmodulin-responsive adenylate cyclase activity  fibroblast growth factor receptor signaling pathway  membrane  integral to membrane  protein kinase binding  microvillus membrane  activation of protein kinase A activity  intracellular signal transduction  sarcolemma  small molecule metabolic process  membrane raft  metal ion binding  nerve growth factor receptor signaling pathway  transmembrane transport  cellular response to glucagon stimulus  cellular response to prostaglandin E stimulus  cellular response to catecholamine stimulus  
Ontology : EGO-EBIadenylate cyclase activity  receptor binding  protein binding  ATP binding  endosome  plasma membrane  cilium  energy reserve metabolic process  cAMP biosynthetic process  water transport  signal transduction  epidermal growth factor receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  activation of phospholipase C activity  dopamine receptor signaling pathway  synaptic transmission  calcium- and calmodulin-responsive adenylate cyclase activity  fibroblast growth factor receptor signaling pathway  membrane  integral to membrane  protein kinase binding  microvillus membrane  activation of protein kinase A activity  intracellular signal transduction  sarcolemma  small molecule metabolic process  membrane raft  metal ion binding  nerve growth factor receptor signaling pathway  transmembrane transport  cellular response to glucagon stimulus  cellular response to prostaglandin E stimulus  cellular response to catecholamine stimulus  
Pathways : KEGGGap junctionGnRH signaling pathwayTaste transductionPurine metabolism
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
PubGeneADCY6
iHOPADCY6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:20:40 CEST 2013
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