Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ADCY7 (adenylate cyclase 7)

Identity

Alias_symbol (synonym)KIAA0037
AC7
Other alias
HGNC (Hugo) ADCY7
LocusID (NCBI) 113
Atlas_Id 580
Location 16q12.1  [Link to chromosome band 16q12]
Location_base_pair Starts at 50321823 and ends at 50352045 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
JA040725 () / ADCY7 (16q12.1)NKD1 (16q12.1) / ADCY7 (16q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADCY7   238
Cards
Entrez_Gene (NCBI)ADCY7  113  adenylate cyclase 7
AliasesAC7
GeneCards (Weizmann)ADCY7
Ensembl hg19 (Hinxton)ENSG00000121281 [Gene_View]  chr16:50321823-50352045 [Contig_View]  ADCY7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000121281 [Gene_View]  chr16:50321823-50352045 [Contig_View]  ADCY7 [Vega]
ICGC DataPortalENSG00000121281
TCGA cBioPortalADCY7
AceView (NCBI)ADCY7
Genatlas (Paris)ADCY7
WikiGenes113
SOURCE (Princeton)ADCY7
Genetics Home Reference (NIH)ADCY7
Genomic and cartography
GoldenPath hg19 (UCSC)ADCY7  -     chr16:50321823-50352045 +  16q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ADCY7  -     16q12.1   [Description]    (hg38-Dec_2013)
EnsemblADCY7 - 16q12.1 [CytoView hg19]  ADCY7 - 16q12.1 [CytoView hg38]
Mapping of homologs : NCBIADCY7 [Mapview hg19]  ADCY7 [Mapview hg38]
OMIM600385   
Gene and transcription
Genbank (Entrez)AA740624 AK093706 BC039891 BC098566 BC126271
RefSeq transcript (Entrez)NM_001114 NM_001286057
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)ADCY7
Cluster EST : UnigeneHs.513578 [ NCBI ]
CGAP (NCI)Hs.513578
Alternative Splicing GalleryENSG00000121281
Gene ExpressionADCY7 [ NCBI-GEO ]   ADCY7 [ EBI - ARRAY_EXPRESS ]   ADCY7 [ SEEK ]   ADCY7 [ MEM ]
Gene Expression Viewer (FireBrowse)ADCY7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113
GTEX Portal (Tissue expression)ADCY7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51828   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51828  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51828
Splice isoforms : SwissVarP51828
Catalytic activity : Enzyme4.6.1.1 [ Enzyme-Expasy ]   4.6.1.14.6.1.1 [ IntEnz-EBI ]   4.6.1.1 [ BRENDA ]   4.6.1.1 [ KEGG ]   
PhosPhoSitePlusP51828
Domaine pattern : Prosite (Expaxy)GUANYLATE_CYCLASE_1 (PS00452)    GUANYLATE_CYCLASE_2 (PS50125)   
Domains : Interpro (EBI)A/G_cyclase    A/G_cyclase_CS    AC_N    Adcy    Adcy_conserved_dom    Nucleotide_cyclase   
Domain families : Pfam (Sanger)AC_N (PF16214)    DUF1053 (PF06327)    Guanylate_cyc (PF00211)   
Domain families : Pfam (NCBI)pfam16214    pfam06327    pfam00211   
Domain families : Smart (EMBL)CYCc (SM00044)  
Conserved Domain (NCBI)ADCY7
DMDM Disease mutations113
Blocks (Seattle)ADCY7
SuperfamilyP51828
Human Protein AtlasENSG00000121281
Peptide AtlasP51828
HPRD02663
IPIIPI00020920   IPI01013859   IPI01013383   
Protein Interaction databases
DIP (DOE-UCLA)P51828
IntAct (EBI)P51828
FunCoupENSG00000121281
BioGRIDADCY7
STRING (EMBL)ADCY7
ZODIACADCY7
Ontologies - Pathways
QuickGOP51828
Ontology : AmiGOrenal water homeostasis  adenylate cyclase activity  ATP binding  intracellular  intracellular  plasma membrane  plasma membrane  plasma membrane  cAMP biosynthetic process  adenylate cyclase-activating G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  integral component of membrane  cAMP-mediated signaling  positive regulation of cAMP biosynthetic process  activation of protein kinase A activity  metal ion binding  maternal process involved in female pregnancy  cellular response to ethanol  cellular response to glucagon stimulus  
Ontology : EGO-EBIrenal water homeostasis  adenylate cyclase activity  ATP binding  intracellular  intracellular  plasma membrane  plasma membrane  plasma membrane  cAMP biosynthetic process  adenylate cyclase-activating G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  integral component of membrane  cAMP-mediated signaling  positive regulation of cAMP biosynthetic process  activation of protein kinase A activity  metal ion binding  maternal process involved in female pregnancy  cellular response to ethanol  cellular response to glucagon stimulus  
Pathways : KEGGPurine metabolism    Rap1 signaling pathway    Calcium signaling pathway    Chemokine signaling pathway    Oocyte meiosis    Adrenergic signaling in cardiomyocytes    Vascular smooth muscle contraction    Gap junction    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    GABAergic synapse    Insulin secretion    GnRH signaling pathway    Ovarian steroidogenesis    Progesterone-mediated oocyte maturation    Estrogen signaling pathway    Melanogenesis    Thyroid hormone synthesis    Salivary secretion    Gastric acid secretion    Pancreatic secretion    Bile secretion    Morphine addiction    HTLV-I infection    Dilated cardiomyopathy   
NDEx NetworkADCY7
Atlas of Cancer Signalling NetworkADCY7
Wikipedia pathwaysADCY7
Orthology - Evolution
OrthoDB113
GeneTree (enSembl)ENSG00000121281
Phylogenetic Trees/Animal Genes : TreeFamADCY7
HOVERGENP51828
HOGENOMP51828
Homologs : HomoloGeneADCY7
Homology/Alignments : Family Browser (UCSC)ADCY7
Gene fusions - Rearrangements
Fusion Cancer (Beijing)JA040725 [ADCY7]  -  16q12.1 [FUSC001177]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADCY7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADCY7
dbVarADCY7
ClinVarADCY7
1000_GenomesADCY7 
Exome Variant ServerADCY7
ExAC (Exome Aggregation Consortium)ADCY7 (select the gene name)
Genetic variants : HAPMAP113
Genomic Variants (DGV)ADCY7 [DGVbeta]
DECIPHER (Syndromes)16:50321823-50352045  ENSG00000121281
CONAN: Copy Number AnalysisADCY7 
Mutations
ICGC Data PortalADCY7 
TCGA Data PortalADCY7 
Broad Tumor PortalADCY7
OASIS PortalADCY7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADCY7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADCY7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADCY7
DgiDB (Drug Gene Interaction Database)ADCY7
DoCM (Curated mutations)ADCY7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADCY7 (select a term)
intoGenADCY7
Cancer3DADCY7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600385   
Orphanet
MedgenADCY7
Genetic Testing Registry ADCY7
NextProtP51828 [Medical]
TSGene113
GENETestsADCY7
Huge Navigator ADCY7 [HugePedia]
snp3D : Map Gene to Disease113
BioCentury BCIQADCY7
ClinGenADCY7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD113
Chemical/Pharm GKB GenePA28
Clinical trialADCY7
Miscellaneous
canSAR (ICR)ADCY7 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADCY7
EVEXADCY7
GoPubMedADCY7
iHOPADCY7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:51:39 CEST 2017

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