Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ADCYAP1 (adenylate cyclase activating polypeptide 1 (pituitary))

Identity

Other namesPACAP
HGNC (Hugo) ADCYAP1
LocusID (NCBI) 116
Location 18p11.32
Location_base_pair Starts at 904944 and ends at 912173 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADCYAP1   241
Entrez_Gene (NCBI)ADCYAP1  116  adenylate cyclase activating polypeptide 1 (pituitary)
Cards
GeneCards (Weizmann)ADCYAP1
Ensembl (Hinxton)ENSG00000141433 [Gene_View]  chr18:904944-912173 [Contig_View]  ADCYAP1 [Vega]
AceView (NCBI)ADCYAP1
Genatlas (Paris)ADCYAP1
SOURCE (Stanford)NM_001099733 NM_001117
Genomic and cartography
GoldenPath (UCSC)ADCYAP1  -  18p11.32   chr18:904944-912173 +  18p11.32   [Description]    (hg19-Feb_2009)
EnsemblADCYAP1 - 18p11.32 [CytoView]
Mapping of homologs : NCBIADCYAP1 [Mapview]
OMIM102980   
Gene and transcription
Genbank (Entrez)AB537500 AK294233 AK313050 BC093837 BC101803
RefSeq transcript (SRS)NM_001099733 NM_001117
RefSeq transcript (Entrez)NM_001099733 NM_001117
RefSeq genomic (SRS)AC_000150 NC_000018 NC_018929 NT_010859 NW_001838461 NW_004078094
RefSeq genomic (Entrez)AC_000150 NC_000018 NC_018929 NT_010859 NW_001838461 NW_004078094
Consensus coding sequences : CCDS (NCBI)ADCYAP1
Cluster EST : UnigeneHs.727476 [ SRS ] Hs.727476 [ NCBI ]
CGAP (NCI)Hs.727476
Alternative Splicing : Fast-db (Paris)GSHG0013870
Alternative Splicing GalleryENSG00000141433
Gene ExpressionADCYAP1 [ NCBI-GEO ]   ADCYAP1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP18509 (SRS) P18509 (Uniprot)
NextProtP18509
With graphics : InterProP18509
Splice isoforms : SwissVarP18509(Swissvar)
Domaine pattern : Prosite (SRS)GLUCAGON (PS00260)   
Domaine pattern : Prosite (Expaxy)GLUCAGON (PS00260)   
Domains : Interpro (SRS)Glucagon_GIP_secretin_VIP   
Domains : Interpro (EBI)Glucagon_GIP_secretin_VIP   
Related proteins : CluSTrP18509
Domain families : Pfam (SRS)Hormone_2 (PF00123)   
Domain families : Pfam (Sanger)Hormone_2 (PF00123)   
Domain families : Pfam (NCBI)pfam00123   
Domain families : Smart (EMBL)GLUCA (SM00070)  
DMDM116
Blocks (Seattle)P18509
PDB (SRS)1GEA    2D2P    2JOD   
PDB (PDBSum)1GEA    2D2P    2JOD   
PDB (IMB)1GEA    2D2P    2JOD   
PDB (RSDB)1GEA    2D2P    2JOD   
Human Protein AtlasENSG00000141433
HPRD02369
IPIIPI01010404   IPI00000027   
Protein Interaction databases
DIP (DOE-UCLA)P18509
IntAct (EBI)P18509
FunCoupENSG00000141433
REACTOMEADCYAP1
Protein Interaction Database116
BioGRIDADCYAP1
InParanoidP18509
Interologous Interaction database P18509
IntegromeDBADCYAP1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ADCYAP1
SNP (GeneSNP Utah)ADCYAP1
SNP : HGBaseADCYAP1
Genetic variants : HAPMAPADCYAP1
Somatic Mutations in Cancer : COSMICADCYAP1 
CONAN: Copy Number AnalysisADCYAP1 
Mutations and Diseases : HGMDADCYAP1
OMIM102980   
GENETests102980   
Disease Genetic AssociationADCYAP1
Huge Navigator ADCYAP1 [HugePedia]  ADCYAP1 [HugeCancerGEM]
Genomic VariantsADCYAP1  ADCYAP1 [DGVbeta]
ClinVarADCYAP1
snp3D : Map Gene to Disease116
General knowledge
Homologs : HomoloGeneADCYAP1
Homology/Alignments : Family Browser (UCSC)ADCYAP1
Phylogenetic Trees/Animal Genes : TreeFamADCYAP1
Chemical/Protein Interactions : CTD116
Chemical/Pharm GKB GenePA24564
Clinical trialADCYAP1
Cancer Resource (Charite)ENSG00000141433
Ontology : AmiGOovarian follicle development  behavioral fear response  histamine secretion  negative regulation of acute inflammatory response to antigenic stimulus  negative regulation of acute inflammatory response to non-antigenic stimulus  receptor signaling protein activity  receptor binding  neuropeptide hormone activity  extracellular region  extracellular space  transmembrane receptor protein tyrosine kinase signaling pathway  activation of adenylate cyclase activity  elevation of cytosolic calcium ion concentration  cell-cell signaling  female pregnancy  regulation of G-protein coupled receptor protein signaling pathway  positive regulation of cell proliferation  positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway  positive regulation of neuron projection development  pituitary adenylate cyclase activating polypeptide activity  sensory perception of pain  pituitary gland development  pituitary adenylate cyclase-activating polypeptide receptor binding  positive regulation of interleukin-6 production  regulation of protein localization  negative regulation of Rho GTPase activity  response to starvation  terminal bouton  negative regulation of potassium ion transport  response to ethanol  negative regulation of cell cycle  positive regulation of vasodilation  ATP metabolic process  neurotrophin TRK receptor signaling pathway  peptide hormone receptor binding  peptide hormone receptor binding  positive regulation of synaptic transmission, glutamatergic  regulation of postsynaptic membrane potential  positive regulation of growth hormone secretion  negative regulation of glial cell proliferation  regulation of oligodendrocyte progenitor proliferation  cellular response to glucocorticoid stimulus  positive regulation of somatostatin secretion  
Ontology : EGO-EBIovarian follicle development  behavioral fear response  histamine secretion  negative regulation of acute inflammatory response to antigenic stimulus  negative regulation of acute inflammatory response to non-antigenic stimulus  receptor signaling protein activity  receptor binding  neuropeptide hormone activity  extracellular region  extracellular space  transmembrane receptor protein tyrosine kinase signaling pathway  activation of adenylate cyclase activity  elevation of cytosolic calcium ion concentration  cell-cell signaling  female pregnancy  regulation of G-protein coupled receptor protein signaling pathway  positive regulation of cell proliferation  positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway  positive regulation of neuron projection development  pituitary adenylate cyclase activating polypeptide activity  sensory perception of pain  pituitary gland development  pituitary adenylate cyclase-activating polypeptide receptor binding  positive regulation of interleukin-6 production  regulation of protein localization  negative regulation of Rho GTPase activity  response to starvation  terminal bouton  negative regulation of potassium ion transport  response to ethanol  negative regulation of cell cycle  positive regulation of vasodilation  ATP metabolic process  neurotrophin TRK receptor signaling pathway  peptide hormone receptor binding  peptide hormone receptor binding  positive regulation of synaptic transmission, glutamatergic  regulation of postsynaptic membrane potential  positive regulation of growth hormone secretion  negative regulation of glial cell proliferation  regulation of oligodendrocyte progenitor proliferation  cellular response to glucocorticoid stimulus  positive regulation of somatostatin secretion  
Pathways : KEGGNeuroactive ligand-receptor interaction
Other databases
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
PubGeneADCYAP1
iHOPADCYAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:41:09 CEST 2013
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