Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ADCYAP1R1 (adenylate cyclase activating polypeptide 1 (pituitary) receptor type I)

Identity

Other namesPAC1
PAC1R
PACAPR
PACAPRI
HGNC (Hugo) ADCYAP1R1
LocusID (NCBI) 117
Location 7p14.3
Location_base_pair Starts at 31092076 and ends at 31151093 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADCYAP1R1   242
Entrez_Gene (NCBI)ADCYAP1R1  117  adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
Cards
GeneCards (Weizmann)ADCYAP1R1
Ensembl (Hinxton)ENSG00000078549 [Gene_View]  chr7:31092076-31151093 [Contig_View]  ADCYAP1R1 [Vega]
AceView (NCBI)ADCYAP1R1
Genatlas (Paris)ADCYAP1R1
SOURCE (Stanford)NM_001118 NM_001199635 NM_001199636 NM_001199637
Genomic and cartography
GoldenPath (UCSC)ADCYAP1R1  -  7p14.3   chr7:31092076-31151093 +  7p14.3   [Description]    (hg19-Feb_2009)
EnsemblADCYAP1R1 - 7p14.3 [CytoView]
Mapping of homologs : NCBIADCYAP1R1 [Mapview]
OMIM102981   
Gene and transcription
Genbank (Entrez)AI815550 AK096545 AK124304 AK226138 AK290046
RefSeq transcript (SRS)NM_001118 NM_001199635 NM_001199636 NM_001199637
RefSeq transcript (Entrez)NM_001118 NM_001199635 NM_001199636 NM_001199637
RefSeq genomic (SRS)AC_000068 AC_000139 NC_000007 NC_018918 NG_029869 NT_007819 NT_079592 NW_001839003 NW_004078029
RefSeq genomic (Entrez)AC_000068 AC_000139 NC_000007 NC_018918 NG_029869 NT_007819 NT_079592 NW_001839003 NW_004078029
Consensus coding sequences : CCDS (NCBI)ADCYAP1R1
Cluster EST : UnigeneHs.377783 [ SRS ] Hs.377783 [ NCBI ]
CGAP (NCI)Hs.377783
Alternative Splicing : Fast-db (Paris)GSHG0027258
Alternative Splicing GalleryENSG00000078549
Gene ExpressionADCYAP1R1 [ NCBI-GEO ]   ADCYAP1R1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41586 (SRS) P41586 (Uniprot)
NextProtP41586
With graphics : InterProP41586
Splice isoforms : SwissVarP41586(Swissvar)
Domaine pattern : Prosite (SRS)G_PROTEIN_RECEP_F2_1 (PS00649)    G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_3 (PS50227)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_1 (PS00649)    G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_3 (PS50227)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domains : Interpro (SRS)GPCR_2-like    GPCR_2_extracellular_dom    GPCR_2_PACAP_1_rcpt    GPCR_2_secretin-like    GPCR_2_secretin-like_CS   
Domains : Interpro (EBI)GPCR_2-like    GPCR_2_extracellular_dom    GPCR_2_PACAP_1_rcpt    GPCR_2_secretin-like    GPCR_2_secretin-like_CS   
Related proteins : CluSTrP41586
Domain families : Pfam (SRS)7tm_2 (PF00002)    HRM (PF02793)   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    HRM (PF02793)   
Domain families : Pfam (NCBI)pfam00002    pfam02793   
Domain families : Smart (EMBL)HormR (SM00008)  
DMDM117
Blocks (Seattle)P41586
PDB (SRS)2JOD    3N94   
PDB (PDBSum)2JOD    3N94   
PDB (IMB)2JOD    3N94   
PDB (RSDB)2JOD    3N94   
Human Protein AtlasENSG00000078549
HPRD00045
IPIIPI00299406   IPI00434023   IPI00983773   IPI00917967   IPI00437612   IPI00437613   IPI00915782   
Protein Interaction databases
DIP (DOE-UCLA)P41586
IntAct (EBI)P41586
FunCoupENSG00000078549
REACTOMEADCYAP1R1
Protein Interaction Database117
BioGRIDADCYAP1R1
InParanoidP41586
Interologous Interaction database P41586
IntegromeDBADCYAP1R1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ADCYAP1R1
SNP (GeneSNP Utah)ADCYAP1R1
SNP : HGBaseADCYAP1R1
Genetic variants : HAPMAPADCYAP1R1
Somatic Mutations in Cancer : COSMICADCYAP1R1 
CONAN: Copy Number AnalysisADCYAP1R1 
Mutations and Diseases : HGMDADCYAP1R1
OMIM102981   
GENETests102981   
Disease Genetic AssociationADCYAP1R1
Huge Navigator ADCYAP1R1 [HugePedia]  ADCYAP1R1 [HugeCancerGEM]
Genomic VariantsADCYAP1R1  ADCYAP1R1 [DGVbeta]
ClinVarADCYAP1R1
snp3D : Map Gene to Disease117
General knowledge
Homologs : HomoloGeneADCYAP1R1
Homology/Alignments : Family Browser (UCSC)ADCYAP1R1
Phylogenetic Trees/Animal Genes : TreeFamADCYAP1R1
Chemical/Protein Interactions : CTD117
Chemical/Pharm GKB GenePA24565
Clinical trialADCYAP1R1
Cancer Resource (Charite)ENSG00000078549
Ontology : AmiGOreceptor activity  vasoactive intestinal polypeptide receptor activity  protein binding  endosome  rough endoplasmic reticulum  plasma membrane  integral to plasma membrane  caveola  tight junction  cell surface receptor signaling pathway  transmembrane receptor protein tyrosine kinase signaling pathway  activation of adenylate cyclase activity  activation of phospholipase C activity  spermatogenesis  adenylate cyclase binding  cell surface  positive regulation of calcium ion transport into cytosol  cAMP-mediated signaling  cell differentiation  ADP-ribosylation factor binding  response to estradiol stimulus  multicellular organismal response to stress  response to drug  neuropeptide binding  neuron projection  response to ethanol  development of primary female sexual characteristics  neurotrophin TRK receptor signaling pathway  negative regulation of cell death  positive regulation of inositol phosphate biosynthetic process  
Ontology : EGO-EBIreceptor activity  vasoactive intestinal polypeptide receptor activity  protein binding  endosome  rough endoplasmic reticulum  plasma membrane  integral to plasma membrane  caveola  tight junction  cell surface receptor signaling pathway  transmembrane receptor protein tyrosine kinase signaling pathway  activation of adenylate cyclase activity  activation of phospholipase C activity  spermatogenesis  adenylate cyclase binding  cell surface  positive regulation of calcium ion transport into cytosol  cAMP-mediated signaling  cell differentiation  ADP-ribosylation factor binding  response to estradiol stimulus  multicellular organismal response to stress  response to drug  neuropeptide binding  neuron projection  response to ethanol  development of primary female sexual characteristics  neurotrophin TRK receptor signaling pathway  negative regulation of cell death  positive regulation of inositol phosphate biosynthetic process  
Pathways : KEGGNeuroactive ligand-receptor interaction
Other databases
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
PubGeneADCYAP1R1
iHOPADCYAP1R1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:52:40 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.