Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ADD1 (adducin 1)

Identity

Alias_namesadducin 1 (alpha)
Other aliasADDA
HGNC (Hugo) ADD1
LocusID (NCBI) 118
Atlas_Id 53920
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 2843857 and ends at 2930075 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADD1 (4p16.3) / ADD1 (4p16.3)ADD1 (4p16.3) / ADK (10q22.2)ADD1 (4p16.3) / ATP2B4 (1q32.1)
ADD1 (4p16.3) / CAST (5q15)ADD1 (4p16.3) / FAM193A (4p16.3)ADD1 (4p16.3) / NEAT1 (11q13.1)
ADD1 (4p16.3) / RRM2 (2p25.1)ADD1 (4p16.3) / SH3BP2 (4p16.3)ADD1 (4p16.3) / SLC24A2 (9p22.1)
C1orf61 (1q22) / ADD1 (4p16.3)NUDT4 (12q22) / ADD1 (4p16.3)POLN (4p16.3) / ADD1 (4p16.3)
SH3BP2 (4p16.3) / ADD1 (4p16.3)ADD1 4p16.3 / ADK 10q22.2ADD1 4p16.3 / ATP2B4 1q32.1
ADD1 4p16.3 / FAM193A 4p16.3ADD1 4p16.3 / SH3BP2 4p16.3NUDT4 12q22 / ADD1 4p16.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADD1   243
Cards
Entrez_Gene (NCBI)ADD1  118  adducin 1
AliasesADDA
GeneCards (Weizmann)ADD1
Ensembl hg19 (Hinxton)ENSG00000087274 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087274 [Gene_View]  chr4:2843857-2930075 [Contig_View]  ADD1 [Vega]
ICGC DataPortalENSG00000087274
TCGA cBioPortalADD1
AceView (NCBI)ADD1
Genatlas (Paris)ADD1
WikiGenes118
SOURCE (Princeton)ADD1
Genetics Home Reference (NIH)ADD1
Genomic and cartography
GoldenPath hg38 (UCSC)ADD1  -     chr4:2843857-2930075 +  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADD1  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblADD1 - 4p16.3 [CytoView hg19]  ADD1 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIADD1 [Mapview hg19]  ADD1 [Mapview hg38]
OMIM102680   145500   
Gene and transcription
Genbank (Entrez)AH004560 AH004561 AK025413 AK295457 AK298523
RefSeq transcript (Entrez)NM_001119 NM_001286645 NM_014189 NM_014190 NM_176801
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADD1
Cluster EST : UnigeneHs.183706 [ NCBI ]
CGAP (NCI)Hs.183706
Alternative Splicing GalleryENSG00000087274
Gene ExpressionADD1 [ NCBI-GEO ]   ADD1 [ EBI - ARRAY_EXPRESS ]   ADD1 [ SEEK ]   ADD1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118
GTEX Portal (Tissue expression)ADD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35611   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP35611  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP35611
Splice isoforms : SwissVarP35611
PhosPhoSitePlusP35611
Domains : Interpro (EBI)ADD1    Aldolase_II/adducin_N   
Domain families : Pfam (Sanger)Aldolase_II (PF00596)   
Domain families : Pfam (NCBI)pfam00596   
Domain families : Smart (EMBL)Aldolase_II (SM01007)  
Conserved Domain (NCBI)ADD1
DMDM Disease mutations118
Blocks (Seattle)ADD1
SuperfamilyP35611
Human Protein AtlasENSG00000087274
Peptide AtlasP35611
HPRD00036
IPIIPI00019901   IPI00220158   IPI00253279   IPI00376220   IPI00965619   IPI00964151   IPI00965916   IPI00965403   IPI00964204   IPI01014181   IPI01013851   
Protein Interaction databases
DIP (DOE-UCLA)P35611
IntAct (EBI)P35611
FunCoupENSG00000087274
BioGRIDADD1
STRING (EMBL)ADD1
ZODIACADD1
Ontologies - Pathways
QuickGOP35611
Ontology : AmiGOcell morphogenesis  in utero embryonic development  RNA binding  actin binding  structural molecule activity  calmodulin binding  nucleus  nucleoplasm  cytoplasm  cytosol  plasma membrane  plasma membrane  cell-cell adherens junction  focal adhesion  cell volume homeostasis  transcription factor binding  F-actin capping protein complex  nuclear body  hemoglobin metabolic process  actin cytoskeleton organization  erythrocyte differentiation  spectrin binding  positive regulation of protein binding  multicellular organism growth  IRE1-mediated unfolded protein response  protein homodimerization activity  cadherin binding  protein heterodimerization activity  homeostasis of number of cells within a tissue  actin filament binding  barbed-end actin filament capping  actin filament bundle assembly  transmembrane transport  cellular response to calcium ion  positive regulation of establishment of endothelial barrier  positive regulation of adherens junction organization  
Ontology : EGO-EBIcell morphogenesis  in utero embryonic development  RNA binding  actin binding  structural molecule activity  calmodulin binding  nucleus  nucleoplasm  cytoplasm  cytosol  plasma membrane  plasma membrane  cell-cell adherens junction  focal adhesion  cell volume homeostasis  transcription factor binding  F-actin capping protein complex  nuclear body  hemoglobin metabolic process  actin cytoskeleton organization  erythrocyte differentiation  spectrin binding  positive regulation of protein binding  multicellular organism growth  IRE1-mediated unfolded protein response  protein homodimerization activity  cadherin binding  protein heterodimerization activity  homeostasis of number of cells within a tissue  actin filament binding  barbed-end actin filament capping  actin filament bundle assembly  transmembrane transport  cellular response to calcium ion  positive regulation of establishment of endothelial barrier  positive regulation of adherens junction organization  
Pathways : BIOCARTASynaptic Proteins at the Synaptic Junction [Genes]   
NDEx NetworkADD1
Atlas of Cancer Signalling NetworkADD1
Wikipedia pathwaysADD1
Orthology - Evolution
OrthoDB118
GeneTree (enSembl)ENSG00000087274
Phylogenetic Trees/Animal Genes : TreeFamADD1
HOVERGENP35611
HOGENOMP35611
Homologs : HomoloGeneADD1
Homology/Alignments : Family Browser (UCSC)ADD1
Gene fusions - Rearrangements
Fusion : MitelmanADD1/ADK [4p16.3/10q22.2]  
Fusion : MitelmanADD1/ATP2B4 [4p16.3/1q32.1]  [t(1;4)(q32;p16)]  
Fusion : MitelmanADD1/FAM193A [4p16.3/4p16.3]  [t(4;4)(p16;p16)]  
Fusion : MitelmanADD1/SH3BP2 [4p16.3/4p16.3]  [t(4;4)(p16;p16)]  
Fusion : MitelmanNUDT4/ADD1 [12q22/4p16.3]  [t(4;12)(p16;q22)]  
Fusion: TCGAADD1 4p16.3 ADK 10q22.2 HNSC
Fusion: TCGAADD1 4p16.3 ATP2B4 1q32.1 LGG
Fusion: TCGAADD1 4p16.3 FAM193A 4p16.3 LUSC OV
Fusion: TCGAADD1 4p16.3 SH3BP2 4p16.3 BRCA OV
Fusion: TCGANUDT4 12q22 ADD1 4p16.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADD1
dbVarADD1
ClinVarADD1
1000_GenomesADD1 
Exome Variant ServerADD1
ExAC (Exome Aggregation Consortium)ADD1 (select the gene name)
Genetic variants : HAPMAP118
Genomic Variants (DGV)ADD1 [DGVbeta]
DECIPHERADD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADD1 
Mutations
ICGC Data PortalADD1 
TCGA Data PortalADD1 
Broad Tumor PortalADD1
OASIS PortalADD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADD1
DgiDB (Drug Gene Interaction Database)ADD1
DoCM (Curated mutations)ADD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADD1 (select a term)
intoGenADD1
Cancer3DADD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM102680    145500   
Orphanet
MedgenADD1
Genetic Testing Registry ADD1
NextProtP35611 [Medical]
TSGene118
GENETestsADD1
Target ValidationADD1
Huge Navigator ADD1 [HugePedia]
snp3D : Map Gene to Disease118
BioCentury BCIQADD1
ClinGenADD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD118
Chemical/Pharm GKB GenePA31
Clinical trialADD1
Miscellaneous
canSAR (ICR)ADD1 (select the gene name)
Probes
Litterature
PubMed213 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADD1
EVEXADD1
GoPubMedADD1
iHOPADD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:22:52 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.