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ADD2 (adducin 2)

Identity

Other aliasADDB
HGNC (Hugo) ADD2
LocusID (NCBI) 119
Atlas_Id 56758
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 70662084 and ends at 70767715 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADD2   244
Cards
Entrez_Gene (NCBI)ADD2  119  adducin 2
AliasesADDB
GeneCards (Weizmann)ADD2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:70662084-70767715 [Contig_View]  ADD2 [Vega]
TCGA cBioPortalADD2
AceView (NCBI)ADD2
Genatlas (Paris)ADD2
WikiGenes119
SOURCE (Princeton)ADD2
Genetics Home Reference (NIH)ADD2
Genomic and cartography
GoldenPath hg38 (UCSC)ADD2  -     chr2:70662084-70767715 -  2p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADD2  -     2p13.3   [Description]    (hg19-Feb_2009)
EnsemblADD2 - 2p13.3 [CytoView hg19]  ADD2 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIADD2 [Mapview hg19]  ADD2 [Mapview hg38]
OMIM102681   
Gene and transcription
Genbank (Entrez)AB209227 AB593080 AF038185 AF486420 AF486421
RefSeq transcript (Entrez)NM_001185054 NM_001185055 NM_001617 NM_017482 NM_017483 NM_017484 NM_017485 NM_017486 NM_017487 NM_017488
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADD2
Cluster EST : UnigeneHs.188528 [ NCBI ]
CGAP (NCI)Hs.188528
Gene ExpressionADD2 [ NCBI-GEO ]   ADD2 [ EBI - ARRAY_EXPRESS ]   ADD2 [ SEEK ]   ADD2 [ MEM ]
Gene Expression Viewer (FireBrowse)ADD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)119
GTEX Portal (Tissue expression)ADD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35612   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP35612  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP35612
Splice isoforms : SwissVarP35612
PhosPhoSitePlusP35612
Domains : Interpro (EBI)ADD2    Aldolase_II/adducin_N   
Domain families : Pfam (Sanger)Aldolase_II (PF00596)   
Domain families : Pfam (NCBI)pfam00596   
Domain families : Smart (EMBL)Aldolase_II (SM01007)  
Conserved Domain (NCBI)ADD2
DMDM Disease mutations119
Blocks (Seattle)ADD2
SuperfamilyP35612
Peptide AtlasP35612
IPIIPI00019904   IPI00220240   IPI00220241   IPI00654787   IPI00981413   IPI00719156   IPI01017944   IPI00942277   IPI00978930   IPI00924848   IPI00927261   IPI00943213   
Protein Interaction databases
DIP (DOE-UCLA)P35612
IntAct (EBI)P35612
BioGRIDADD2
STRING (EMBL)ADD2
ZODIACADD2
Ontologies - Pathways
QuickGOP35612
Ontology : AmiGOactin binding  structural molecule activity  calmodulin binding  cytosol  protein complex assembly  F-actin capping protein complex  postsynaptic density  protein kinase binding  actin cytoskeleton organization  hemopoiesis  spectrin binding  cytoplasmic vesicle  positive regulation of protein binding  protein homodimerization activity  plasma membrane raft  protein heterodimerization activity  leukocyte migration  leukocyte tethering or rolling  actin filament binding  barbed-end actin filament capping  actin filament bundle assembly  transmembrane transport  
Ontology : EGO-EBIactin binding  structural molecule activity  calmodulin binding  cytosol  protein complex assembly  F-actin capping protein complex  postsynaptic density  protein kinase binding  actin cytoskeleton organization  hemopoiesis  spectrin binding  cytoplasmic vesicle  positive regulation of protein binding  protein homodimerization activity  plasma membrane raft  protein heterodimerization activity  leukocyte migration  leukocyte tethering or rolling  actin filament binding  barbed-end actin filament capping  actin filament bundle assembly  transmembrane transport  
NDEx NetworkADD2
Atlas of Cancer Signalling NetworkADD2
Wikipedia pathwaysADD2
Orthology - Evolution
OrthoDB119
Phylogenetic Trees/Animal Genes : TreeFamADD2
HOVERGENP35612
HOGENOMP35612
Homologs : HomoloGeneADD2
Homology/Alignments : Family Browser (UCSC)ADD2
Gene fusions - Rearrangements
Tumor Fusion PortalADD2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADD2
dbVarADD2
ClinVarADD2
1000_GenomesADD2 
Exome Variant ServerADD2
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP119
Genomic Variants (DGV)ADD2 [DGVbeta]
DECIPHERADD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADD2 
Mutations
ICGC Data PortalADD2 
TCGA Data PortalADD2 
Broad Tumor PortalADD2
OASIS PortalADD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADD2
BioMutasearch ADD2
DgiDB (Drug Gene Interaction Database)ADD2
DoCM (Curated mutations)ADD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADD2 (select a term)
intoGenADD2
Cancer3DADD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM102681   
Orphanet
DisGeNETADD2
MedgenADD2
Genetic Testing Registry ADD2
NextProtP35612 [Medical]
TSGene119
GENETestsADD2
Target ValidationADD2
Huge Navigator ADD2 [HugePedia]
snp3D : Map Gene to Disease119
BioCentury BCIQADD2
ClinGenADD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD119
Chemical/Pharm GKB GenePA24566
Clinical trialADD2
Miscellaneous
canSAR (ICR)ADD2 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADD2
EVEXADD2
GoPubMedADD2
iHOPADD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:02:12 CET 2017

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