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ADGRB1 (adhesion G protein-coupled receptor B1)

Identity

Alias (NCBI)BAI1
GDAIF
HGNC (Hugo) ADGRB1
HGNC Previous nameBAI1
HGNC Previous namebrain-specific angiogenesis inhibitor 1
LocusID (NCBI) 575
Atlas_Id 749
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 142449649 and ends at 142545007 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADGRB1 (8q24.3)::EXT1 (8q24.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ADGRB1   943
Cards
Entrez_Gene (NCBI)ADGRB1    adhesion G protein-coupled receptor B1
AliasesBAI1; GDAIF
GeneCards (Weizmann)ADGRB1
Ensembl hg19 (Hinxton)ENSG00000181790 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181790 [Gene_View]  ENSG00000181790 [Sequence]  chr8:142449649-142545007 [Contig_View]  ADGRB1 [Vega]
ICGC DataPortalENSG00000181790
TCGA cBioPortalADGRB1
AceView (NCBI)ADGRB1
Genatlas (Paris)ADGRB1
SOURCE (Princeton)ADGRB1
Genetics Home Reference (NIH)ADGRB1
Genomic and cartography
GoldenPath hg38 (UCSC)ADGRB1  -     chr8:142449649-142545007 +  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADGRB1  -     8q24.3   [Description]    (hg19-Feb_2009)
GoldenPathADGRB1 - 8q24.3 [CytoView hg19]  ADGRB1 - 8q24.3 [CytoView hg38]
ImmunoBaseENSG00000181790
Genome Data Viewer NCBIADGRB1 [Mapview hg19]  
OMIM602682   
Gene and transcription
Genbank (Entrez)AB005297 AK123982
RefSeq transcript (Entrez)NM_001391985 NM_001391986 NM_001391987 NM_001391988 NM_001702
Consensus coding sequences : CCDS (NCBI)ADGRB1
Gene ExpressionADGRB1 [ NCBI-GEO ]   ADGRB1 [ EBI - ARRAY_EXPRESS ]   ADGRB1 [ SEEK ]   ADGRB1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADGRB1 [ Firebrowse - Broad ]
GenevisibleExpression of ADGRB1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)575
GTEX Portal (Tissue expression)ADGRB1
Human Protein AtlasENSG00000181790-ADGRB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14514   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14514  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14514
PhosPhoSitePlusO14514
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_3 (PS50227)    G_PROTEIN_RECEP_F2_4 (PS50261)    GPS (PS50221)    TSP1 (PS50092)   
Domains : Interpro (EBI)AGRB_N    GAIN_dom_N    GPCR_2-like    GPCR_2_brain_angio_inhib    GPCR_2_extracell_dom_sf    GPCR_2_extracellular_dom    GPCR_2_secretin-like    GPS    TSP1_rpt    TSP1_rpt_sf   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    AGRB_N (PF19188)    GAIN (PF16489)    GPS (PF01825)    HRM (PF02793)    TSP_1 (PF00090)   
Domain families : Pfam (NCBI)pfam00002    pfam19188    pfam16489    pfam01825    pfam02793    pfam00090   
Domain families : Smart (EMBL)GPS (SM00303)  HormR (SM00008)  TSP1 (SM00209)  
Conserved Domain (NCBI)ADGRB1
SuperfamilyO14514
AlphaFold pdb e-kbO14514   
Human Protein Atlas [tissue]ENSG00000181790-ADGRB1 [tissue]
HPRD04062
Protein Interaction databases
DIP (DOE-UCLA)O14514
IntAct (EBI)O14514
BioGRIDADGRB1
STRING (EMBL)ADGRB1
ZODIACADGRB1
Ontologies - Pathways
QuickGOO14514
Ontology : AmiGOlipopolysaccharide binding  phosphatidylserine binding  phagocytic cup  G protein-coupled receptor activity  G protein-coupled receptor activity  protein binding  extracellular space  plasma membrane  plasma membrane  integral component of plasma membrane  cell-cell junction  focal adhesion  phagocytosis, recognition  cell adhesion  signal transduction  cell surface receptor signaling pathway  G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  axonogenesis  peripheral nervous system development  muscle organ development  negative regulation of cell population proliferation  negative regulation of endothelial cell migration  postsynaptic density  postsynaptic density  integral component of membrane  negative regulation of angiogenesis  PDZ domain binding  dendrite  dendrite  negative regulation of protein ubiquitination  negative regulation of protein catabolic process  dendritic spine  apoptotic cell clearance  engulfment of apoptotic cell  engulfment of apoptotic cell  engulfment of apoptotic cell  innate immune response  regulation of synaptic plasticity  perinuclear region of cytoplasm  defense response to Gram-negative bacterium  positive regulation of synapse assembly  positive regulation of myoblast fusion  positive regulation of reactive oxygen species biosynthetic process  
Ontology : EGO-EBIlipopolysaccharide binding  phosphatidylserine binding  phagocytic cup  G protein-coupled receptor activity  G protein-coupled receptor activity  protein binding  extracellular space  plasma membrane  plasma membrane  integral component of plasma membrane  cell-cell junction  focal adhesion  phagocytosis, recognition  cell adhesion  signal transduction  cell surface receptor signaling pathway  G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  axonogenesis  peripheral nervous system development  muscle organ development  negative regulation of cell population proliferation  negative regulation of endothelial cell migration  postsynaptic density  postsynaptic density  integral component of membrane  negative regulation of angiogenesis  PDZ domain binding  dendrite  dendrite  negative regulation of protein ubiquitination  negative regulation of protein catabolic process  dendritic spine  apoptotic cell clearance  engulfment of apoptotic cell  engulfment of apoptotic cell  engulfment of apoptotic cell  innate immune response  regulation of synaptic plasticity  perinuclear region of cytoplasm  defense response to Gram-negative bacterium  positive regulation of synapse assembly  positive regulation of myoblast fusion  positive regulation of reactive oxygen species biosynthetic process  
NDEx NetworkADGRB1
Atlas of Cancer Signalling NetworkADGRB1
Wikipedia pathwaysADGRB1
Orthology - Evolution
OrthoDB575
GeneTree (enSembl)ENSG00000181790
Phylogenetic Trees/Animal Genes : TreeFamADGRB1
Homologs : HomoloGeneADGRB1
Homology/Alignments : Family Browser (UCSC)ADGRB1
Gene fusions - Rearrangements
Fusion : MitelmanADGRB1::EXT1 [8q24.3/8q24.11]  
Fusion : QuiverADGRB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADGRB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADGRB1
dbVarADGRB1
ClinVarADGRB1
MonarchADGRB1
1000_GenomesADGRB1 
Exome Variant ServerADGRB1
GNOMAD BrowserENSG00000181790
Varsome BrowserADGRB1
ACMGADGRB1 variants
VarityO14514
Genomic Variants (DGV)ADGRB1 [DGVbeta]
DECIPHERADGRB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADGRB1 
Mutations
ICGC Data PortalADGRB1 
TCGA Data PortalADGRB1 
Broad Tumor PortalADGRB1
OASIS PortalADGRB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADGRB1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DADGRB1
Mutations and Diseases : HGMDADGRB1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaADGRB1
DgiDB (Drug Gene Interaction Database)ADGRB1
DoCM (Curated mutations)ADGRB1
CIViC (Clinical Interpretations of Variants in Cancer)ADGRB1
Cancer3DADGRB1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602682   
Orphanet
DisGeNETADGRB1
MedgenADGRB1
Genetic Testing Registry ADGRB1
NextProtO14514 [Medical]
GENETestsADGRB1
Target ValidationADGRB1
Huge Navigator ADGRB1 [HugePedia]
ClinGenADGRB1
Clinical trials, drugs, therapy
MyCancerGenomeADGRB1
Protein Interactions : CTDADGRB1
Pharm GKB GenePA25247
PharosO14514
Clinical trialADGRB1
Miscellaneous
canSAR (ICR)ADGRB1
HarmonizomeADGRB1
ARCHS4ADGRB1
DataMed IndexADGRB1
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXADGRB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jan 17 15:13:43 CET 2022

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