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ADGRD1 (adhesion G protein-coupled receptor D1)

Identity

Alias_namesGPR133
G protein-coupled receptor 133
Alias_symbol (synonym)DKFZp434B1272
PGR25
Other alias
HGNC (Hugo) ADGRD1
LocusID (NCBI) 283383
Atlas_Id 54343
Location 12q24.33  [Link to chromosome band 12q24]
Location_base_pair Starts at 130953907 and ends at 131141468 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADGRD1 (12q24.33) / PHLPP1 (18q21.33)TXNRD1 (12q23.3) / ADGRD1 (12q24.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Adenocarcinoma


External links

Nomenclature
HGNC (Hugo)ADGRD1   19893
Cards
Entrez_Gene (NCBI)ADGRD1  283383  adhesion G protein-coupled receptor D1
AliasesGPR133; PGR25
GeneCards (Weizmann)ADGRD1
Ensembl hg19 (Hinxton)ENSG00000111452 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111452 [Gene_View]  chr12:130953907-131141468 [Contig_View]  ADGRD1 [Vega]
ICGC DataPortalENSG00000111452
TCGA cBioPortalADGRD1
AceView (NCBI)ADGRD1
Genatlas (Paris)ADGRD1
WikiGenes283383
SOURCE (Princeton)ADGRD1
Genetics Home Reference (NIH)ADGRD1
Genomic and cartography
GoldenPath hg38 (UCSC)ADGRD1  -     chr12:130953907-131141468 +  12q24.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADGRD1  -     12q24.33   [Description]    (hg19-Feb_2009)
EnsemblADGRD1 - 12q24.33 [CytoView hg19]  ADGRD1 - 12q24.33 [CytoView hg38]
Mapping of homologs : NCBIADGRD1 [Mapview hg19]  ADGRD1 [Mapview hg38]
OMIM613639   
Gene and transcription
Genbank (Entrez)AK131538 AL162032 AY255587 AY278561 AY532280
RefSeq transcript (Entrez)NM_001330497 NM_198827
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADGRD1
Cluster EST : UnigeneHs.719239 [ NCBI ]
CGAP (NCI)Hs.719239
Alternative Splicing GalleryENSG00000111452
Gene ExpressionADGRD1 [ NCBI-GEO ]   ADGRD1 [ EBI - ARRAY_EXPRESS ]   ADGRD1 [ SEEK ]   ADGRD1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADGRD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283383
GTEX Portal (Tissue expression)ADGRD1
Human Protein AtlasENSG00000111452-ADGRD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6QNK2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6QNK2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6QNK2
Splice isoforms : SwissVarQ6QNK2
PhosPhoSitePlusQ6QNK2
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_4 (PS50261)    GPS (PS50221)    PTX_2 (PS51828)   
Domains : Interpro (EBI)ConA-like_dom    GPCR_2-like    GPCR_2_secretin-like    GPCR_2_secretin-like_CS    GPS   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    GPS (PF01825)   
Domain families : Pfam (NCBI)pfam00002    pfam01825   
Domain families : Smart (EMBL)GPS (SM00303)  
Conserved Domain (NCBI)ADGRD1
DMDM Disease mutations283383
Blocks (Seattle)ADGRD1
SuperfamilyQ6QNK2
Human Protein Atlas [tissue]ENSG00000111452-ADGRD1 [tissue]
Peptide AtlasQ6QNK2
HPRD17061
IPIIPI00394960   IPI0p97874<.A>   IPI00552352   IPI01014587   IPI01015841   IPI00922853   IPI01014961   IPI01012990   IPI01014252   IPI00300123   
Protein Interaction databases
DIP (DOE-UCLA)Q6QNK2
IntAct (EBI)Q6QNK2
FunCoupENSG00000111452
BioGRIDADGRD1
STRING (EMBL)ADGRD1
ZODIACADGRD1
Ontologies - Pathways
QuickGOQ6QNK2
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway  integral component of membrane  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway  integral component of membrane  
NDEx NetworkADGRD1
Atlas of Cancer Signalling NetworkADGRD1
Wikipedia pathwaysADGRD1
Orthology - Evolution
OrthoDB283383
GeneTree (enSembl)ENSG00000111452
Phylogenetic Trees/Animal Genes : TreeFamADGRD1
HOVERGENQ6QNK2
HOGENOMQ6QNK2
Homologs : HomoloGeneADGRD1
Homology/Alignments : Family Browser (UCSC)ADGRD1
Gene fusions - Rearrangements
Fusion: Tumor Portal ADGRD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADGRD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADGRD1
dbVarADGRD1
ClinVarADGRD1
1000_GenomesADGRD1 
Exome Variant ServerADGRD1
ExAC (Exome Aggregation Consortium)ENSG00000111452
GNOMAD BrowserENSG00000111452
Genetic variants : HAPMAP283383
Genomic Variants (DGV)ADGRD1 [DGVbeta]
DECIPHERADGRD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADGRD1 
Mutations
ICGC Data PortalADGRD1 
TCGA Data PortalADGRD1 
Broad Tumor PortalADGRD1
OASIS PortalADGRD1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDADGRD1
BioMutasearch ADGRD1
DgiDB (Drug Gene Interaction Database)ADGRD1
DoCM (Curated mutations)ADGRD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADGRD1 (select a term)
intoGenADGRD1
Cancer3DADGRD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613639   
Orphanet
MedgenADGRD1
Genetic Testing Registry ADGRD1
NextProt
TSGene283383
GENETestsADGRD1
Target ValidationADGRD1
Huge Navigator ADGRD1 [HugePedia]
snp3D : Map Gene to Disease283383
BioCentury BCIQADGRD1
ClinGenADGRD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD283383
Chemical/Pharm GKB GenePA134923933
Clinical trialADGRD1
Miscellaneous
canSAR (ICR)ADGRD1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADGRD1
EVEXADGRD1
GoPubMedADGRD1
iHOPADGRD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:39:24 CET 2017

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