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ADGRF1 (adhesion G protein-coupled receptor F1)

Identity

Alias_namesGPR110
G protein-coupled receptor 110
Alias_symbol (synonym)hGPCR36
PGR19
Other aliasKPG_012
HGNC (Hugo) ADGRF1
LocusID (NCBI) 266977
Atlas_Id 52049
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 46997703 and ends at 47042363 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADGRF1 (6p12.3) / ADGRF1 (6p12.3)ADGRF1 (6p12.3) / MEP1A (6p12.3)ADGRF1 (6p12.3) / TNFRSF21 (6p12.3)
ADGRF1 (6p12.3) / TRERF1 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  ADGRF1/MEP1A (6p12)
t(6;6)(p12;p21) ADGRF1/TRERF1


External links

Nomenclature
HGNC (Hugo)ADGRF1   18990
Cards
Entrez_Gene (NCBI)ADGRF1  266977  adhesion G protein-coupled receptor F1
AliasesGPR110; KPG_012; PGR19; hGPCR36
GeneCards (Weizmann)ADGRF1
Ensembl hg19 (Hinxton)ENSG00000153292 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153292 [Gene_View]  ENSG00000153292 [Sequence]  chr6:46997703-47042363 [Contig_View]  ADGRF1 [Vega]
ICGC DataPortalENSG00000153292
TCGA cBioPortalADGRF1
AceView (NCBI)ADGRF1
Genatlas (Paris)ADGRF1
WikiGenes266977
SOURCE (Princeton)ADGRF1
Genetics Home Reference (NIH)ADGRF1
Genomic and cartography
GoldenPath hg38 (UCSC)ADGRF1  -     chr6:46997703-47042363 -  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADGRF1  -     6p12.3   [Description]    (hg19-Feb_2009)
EnsemblADGRF1 - 6p12.3 [CytoView hg19]  ADGRF1 - 6p12.3 [CytoView hg38]
Mapping of homologs : NCBIADGRF1 [Mapview hg19]  ADGRF1 [Mapview hg38]
OMIM617430   
Gene and transcription
Genbank (Entrez)AB045123 AK026337 AK055208 AK095348 AK225460
RefSeq transcript (Entrez)NM_025048 NM_153840
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADGRF1
Cluster EST : UnigeneHs.733762 [ NCBI ]
CGAP (NCI)Hs.733762
Alternative Splicing GalleryENSG00000153292
Gene ExpressionADGRF1 [ NCBI-GEO ]   ADGRF1 [ EBI - ARRAY_EXPRESS ]   ADGRF1 [ SEEK ]   ADGRF1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADGRF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)266977
GTEX Portal (Tissue expression)ADGRF1
Human Protein AtlasENSG00000153292-ADGRF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T601   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T601  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T601
Splice isoforms : SwissVarQ5T601
PhosPhoSitePlusQ5T601
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_4 (PS50261)    GPS (PS50221)    SEA (PS50024)   
Domains : Interpro (EBI)GPCR_2-like    GPCR_2_Ig-hepta-like_rcpt    GPCR_2_secretin-like    GPS    SEA_dom    SEA_dom_sf   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    GPS (PF01825)    SEA (PF01390)   
Domain families : Pfam (NCBI)pfam00002    pfam01825    pfam01390   
Domain families : Smart (EMBL)GPS (SM00303)  
Conserved Domain (NCBI)ADGRF1
DMDM Disease mutations266977
Blocks (Seattle)ADGRF1
SuperfamilyQ5T601
Human Protein Atlas [tissue]ENSG00000153292-ADGRF1 [tissue]
Peptide AtlasQ5T601
HPRD08661
IPIIPI00879033   IPI00017924   IPI00651683   IPI00552805   IPI01010986   IPI01009944   IPI00947305   IPI00946293   
Protein Interaction databases
DIP (DOE-UCLA)Q5T601
IntAct (EBI)Q5T601
FunCoupENSG00000153292
BioGRIDADGRF1
STRING (EMBL)ADGRF1
ZODIACADGRF1
Ontologies - Pathways
QuickGOQ5T601
Ontology : AmiGOG-protein coupled receptor activity  extracellular region  intracellular  plasma membrane  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  synapse assembly  memory  integral component of membrane  neuron projection development  positive regulation of CREB transcription factor activity  
Ontology : EGO-EBIG-protein coupled receptor activity  extracellular region  intracellular  plasma membrane  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  synapse assembly  memory  integral component of membrane  neuron projection development  positive regulation of CREB transcription factor activity  
NDEx NetworkADGRF1
Atlas of Cancer Signalling NetworkADGRF1
Wikipedia pathwaysADGRF1
Orthology - Evolution
OrthoDB266977
GeneTree (enSembl)ENSG00000153292
Phylogenetic Trees/Animal Genes : TreeFamADGRF1
HOVERGENQ5T601
HOGENOMQ5T601
Homologs : HomoloGeneADGRF1
Homology/Alignments : Family Browser (UCSC)ADGRF1
Gene fusions - Rearrangements
Fusion : MitelmanADGRF1/MEP1A [6p12.3/6p12.3]  
Fusion : MitelmanADGRF1/TRERF1 [6p12.3/6p21.1]  [t(6;6)(p12;p21)]  
Fusion : QuiverADGRF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADGRF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADGRF1
dbVarADGRF1
ClinVarADGRF1
1000_GenomesADGRF1 
Exome Variant ServerADGRF1
ExAC (Exome Aggregation Consortium)ENSG00000153292
GNOMAD BrowserENSG00000153292
Varsome BrowserADGRF1
Genetic variants : HAPMAP266977
Genomic Variants (DGV)ADGRF1 [DGVbeta]
DECIPHERADGRF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADGRF1 
Mutations
ICGC Data PortalADGRF1 
TCGA Data PortalADGRF1 
Broad Tumor PortalADGRF1
OASIS PortalADGRF1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDADGRF1
BioMutasearch ADGRF1
DgiDB (Drug Gene Interaction Database)ADGRF1
DoCM (Curated mutations)ADGRF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADGRF1 (select a term)
intoGenADGRF1
Cancer3DADGRF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617430   
Orphanet
DisGeNETADGRF1
MedgenADGRF1
Genetic Testing Registry ADGRF1
NextProtQ5T601 [Medical]
TSGene266977
GENETestsADGRF1
Target ValidationADGRF1
Huge Navigator ADGRF1 [HugePedia]
snp3D : Map Gene to Disease266977
BioCentury BCIQADGRF1
ClinGenADGRF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD266977
Chemical/Pharm GKB GenePA128394769
Clinical trialADGRF1
Miscellaneous
canSAR (ICR)ADGRF1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADGRF1
EVEXADGRF1
GoPubMedADGRF1
iHOPADGRF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:07:57 CEST 2018

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