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ADGRF5 (adhesion G protein-coupled receptor F5)

Identity

Alias_namesGPR116
G protein-coupled receptor 116
Alias_symbol (synonym)DKFZp564O1923
KIAA0758
Other aliasKPG_001
HGNC (Hugo) ADGRF5
LocusID (NCBI) 221395
Atlas_Id 53899
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 46852506 and ends at 46954938 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADGRF5 (6p12.3) / ADGRF5 (6p12.3)ADGRF5 (6p12.3) / MEP1A (6p12.3)NBPF15 (1q21.2) / ADGRF5 (6p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p12;p12) ADGRF5/MEP1A


External links

Nomenclature
HGNC (Hugo)ADGRF5   19030
Cards
Entrez_Gene (NCBI)ADGRF5  221395  adhesion G protein-coupled receptor F5
AliasesGPR116; KPG_001
GeneCards (Weizmann)ADGRF5
Ensembl hg19 (Hinxton)ENSG00000069122 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000069122 [Gene_View]  ENSG00000069122 [Sequence]  chr6:46852506-46954938 [Contig_View]  ADGRF5 [Vega]
ICGC DataPortalENSG00000069122
TCGA cBioPortalADGRF5
AceView (NCBI)ADGRF5
Genatlas (Paris)ADGRF5
WikiGenes221395
SOURCE (Princeton)ADGRF5
Genetics Home Reference (NIH)ADGRF5
Genomic and cartography
GoldenPath hg38 (UCSC)ADGRF5  -     chr6:46852506-46954938 -  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADGRF5  -     6p12.3   [Description]    (hg19-Feb_2009)
EnsemblADGRF5 - 6p12.3 [CytoView hg19]  ADGRF5 - 6p12.3 [CytoView hg38]
Mapping of homologs : NCBIADGRF5 [Mapview hg19]  ADGRF5 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB018301 AB031421 AI796309 AK075121 AK092043
RefSeq transcript (Entrez)NM_001098518 NM_015234
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADGRF5
Cluster EST : UnigeneHs.362806 [ NCBI ]
CGAP (NCI)Hs.362806
Alternative Splicing GalleryENSG00000069122
Gene ExpressionADGRF5 [ NCBI-GEO ]   ADGRF5 [ EBI - ARRAY_EXPRESS ]   ADGRF5 [ SEEK ]   ADGRF5 [ MEM ]
Gene Expression Viewer (FireBrowse)ADGRF5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221395
GTEX Portal (Tissue expression)ADGRF5
Human Protein AtlasENSG00000069122-ADGRF5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZF2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZF2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZF2
Splice isoforms : SwissVarQ8IZF2
PhosPhoSitePlusQ8IZF2
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_4 (PS50261)    GPS (PS50221)    IG_LIKE (PS50835)    SEA (PS50024)   
Domains : Interpro (EBI)GPCR_2-like    GPCR_2_Ig-hepta-like_rcpt    GPCR_2_secretin-like    GPCR_2_secretin-like_CS    GPS    Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    SEA_dom   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    GPS (PF01825)    SEA (PF01390)   
Domain families : Pfam (NCBI)pfam00002    pfam01825    pfam01390   
Domain families : Smart (EMBL)GPS (SM00303)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)ADGRF5
DMDM Disease mutations221395
Blocks (Seattle)ADGRF5
SuperfamilyQ8IZF2
Human Protein Atlas [tissue]ENSG00000069122-ADGRF5 [tissue]
Peptide AtlasQ8IZF2
HPRD11010
IPIIPI00437186   IPI00967115   IPI00513936   IPI01011763   IPI01011286   IPI00168964   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZF2
IntAct (EBI)Q8IZF2
FunCoupENSG00000069122
BioGRIDADGRF5
STRING (EMBL)ADGRF5
ZODIACADGRF5
Ontologies - Pathways
QuickGOQ8IZF2
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  energy reserve metabolic process  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  cell surface  integral component of membrane  cytoplasmic vesicle  glucose homeostasis  negative regulation of macrophage activation  surfactant homeostasis  apical part of cell  fat cell differentiation  positive regulation of phospholipid biosynthetic process  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  energy reserve metabolic process  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  cell surface  integral component of membrane  cytoplasmic vesicle  glucose homeostasis  negative regulation of macrophage activation  surfactant homeostasis  apical part of cell  fat cell differentiation  positive regulation of phospholipid biosynthetic process  
NDEx NetworkADGRF5
Atlas of Cancer Signalling NetworkADGRF5
Wikipedia pathwaysADGRF5
Orthology - Evolution
OrthoDB221395
GeneTree (enSembl)ENSG00000069122
Phylogenetic Trees/Animal Genes : TreeFamADGRF5
HOVERGENQ8IZF2
HOGENOMQ8IZF2
Homologs : HomoloGeneADGRF5
Homology/Alignments : Family Browser (UCSC)ADGRF5
Gene fusions - Rearrangements
Fusion : MitelmanADGRF5/MEP1A [6p12.3/6p12.3]  
Fusion : QuiverADGRF5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADGRF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADGRF5
dbVarADGRF5
ClinVarADGRF5
1000_GenomesADGRF5 
Exome Variant ServerADGRF5
ExAC (Exome Aggregation Consortium)ENSG00000069122
GNOMAD BrowserENSG00000069122
Genetic variants : HAPMAP221395
Genomic Variants (DGV)ADGRF5 [DGVbeta]
DECIPHERADGRF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADGRF5 
Mutations
ICGC Data PortalADGRF5 
TCGA Data PortalADGRF5 
Broad Tumor PortalADGRF5
OASIS PortalADGRF5 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDADGRF5
BioMutasearch ADGRF5
DgiDB (Drug Gene Interaction Database)ADGRF5
DoCM (Curated mutations)ADGRF5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADGRF5 (select a term)
intoGenADGRF5
Cancer3DADGRF5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETADGRF5
MedgenADGRF5
Genetic Testing Registry ADGRF5
NextProtQ8IZF2 [Medical]
TSGene221395
GENETestsADGRF5
Target ValidationADGRF5
Huge Navigator ADGRF5 [HugePedia]
snp3D : Map Gene to Disease221395
BioCentury BCIQADGRF5
ClinGenADGRF5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221395
Chemical/Pharm GKB GenePA134886165
Clinical trialADGRF5
Miscellaneous
canSAR (ICR)ADGRF5 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADGRF5
EVEXADGRF5
GoPubMedADGRF5
iHOPADGRF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:13:12 CEST 2018

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