Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ADGRG6 (adhesion G protein-coupled receptor G6)

Identity

Alias_namesGPR126
G protein-coupled receptor 126
Alias_symbol (synonym)FLJ14937
Other aliasAPG1
DREG
LCCS9
PR126
PS1TP2
VIGR
HGNC (Hugo) ADGRG6
LocusID (NCBI) 57211
Atlas_Id 76779
Location 6q24.2  [Link to chromosome band 6q24]
Location_base_pair Starts at 142301919 and ends at 142446266 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADGRG6 (6q24.1) / ADGRG6 (6q24.1)ADGRG6 (6q24.1) / CLSTN2 (3q23)ADGRG6 (6q24.1) / VTA1 (6q24.1)
CDK17 (12q23.1) / ADGRG6 (6q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADGRG6   13841
Cards
Entrez_Gene (NCBI)ADGRG6  57211  adhesion G protein-coupled receptor G6
AliasesAPG1; DREG; GPR126; LCCS9; 
PR126; PS1TP2; VIGR
GeneCards (Weizmann)ADGRG6
Ensembl hg19 (Hinxton)ENSG00000112414 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112414 [Gene_View]  chr6:142301919-142446266 [Contig_View]  ADGRG6 [Vega]
ICGC DataPortalENSG00000112414
TCGA cBioPortalADGRG6
AceView (NCBI)ADGRG6
Genatlas (Paris)ADGRG6
WikiGenes57211
SOURCE (Princeton)ADGRG6
Genetics Home Reference (NIH)ADGRG6
Genomic and cartography
GoldenPath hg38 (UCSC)ADGRG6  -     chr6:142301919-142446266 +  6q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADGRG6  -     6q24.2   [Description]    (hg19-Feb_2009)
EnsemblADGRG6 - 6q24.2 [CytoView hg19]  ADGRG6 - 6q24.2 [CytoView hg38]
Mapping of homologs : NCBIADGRG6 [Mapview hg19]  ADGRG6 [Mapview hg38]
OMIM612243   616503   
Gene and transcription
Genbank (Entrez)AB183546 AB183547 AB183548 AB183549 AF216967
RefSeq transcript (Entrez)NM_001032394 NM_001032395 NM_020455 NM_198569
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADGRG6
Cluster EST : UnigeneHs.743302 [ NCBI ]
CGAP (NCI)Hs.743302
Alternative Splicing GalleryENSG00000112414
Gene ExpressionADGRG6 [ NCBI-GEO ]   ADGRG6 [ EBI - ARRAY_EXPRESS ]   ADGRG6 [ SEEK ]   ADGRG6 [ MEM ]
Gene Expression Viewer (FireBrowse)ADGRG6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57211
GTEX Portal (Tissue expression)ADGRG6
Human Protein AtlasENSG00000112414-ADGRG6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86SQ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86SQ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86SQ4
Splice isoforms : SwissVarQ86SQ4
PhosPhoSitePlusQ86SQ4
Domaine pattern : Prosite (Expaxy)CUB (PS01180)    G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_4 (PS50261)    GPS (PS50221)    PTX_2 (PS51828)   
Domains : Interpro (EBI)ConA-like_dom    CUB_dom    GPCR_2-like    GPCR_2_secretin-like    GPCR_2_secretin-like_CS    GPS    Pentraxin-related   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    CUB (PF00431)    GPS (PF01825)    Pentaxin (PF00354)   
Domain families : Pfam (NCBI)pfam00002    pfam00431    pfam01825    pfam00354   
Domain families : Smart (EMBL)CUB (SM00042)  GPS (SM00303)  PTX (SM00159)  
Conserved Domain (NCBI)ADGRG6
DMDM Disease mutations57211
Blocks (Seattle)ADGRG6
SuperfamilyQ86SQ4
Human Protein Atlas [tissue]ENSG00000112414-ADGRG6 [tissue]
Peptide AtlasQ86SQ4
HPRD17059
IPIIPI00217481   IPI00423340   IPI00423342   IPI00651770   IPI01012732   IPI01012318   IPI01013650   IPI01010825   
Protein Interaction databases
DIP (DOE-UCLA)Q86SQ4
IntAct (EBI)Q86SQ4
FunCoupENSG00000112414
BioGRIDADGRG6
STRING (EMBL)ADGRG6
ZODIACADGRG6
Ontologies - Pathways
QuickGOQ86SQ4
Ontology : AmiGOG-protein coupled receptor activity  G-protein coupled receptor activity  collagen binding  intracellular  plasma membrane  mitochondrion organization  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway  Schwann cell differentiation  integral component of membrane  cAMP-mediated signaling  cAMP-mediated signaling  myelination in peripheral nervous system  myelination  laminin binding  extracellular matrix binding  heart trabecula formation  
Ontology : EGO-EBIG-protein coupled receptor activity  G-protein coupled receptor activity  collagen binding  intracellular  plasma membrane  mitochondrion organization  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway  Schwann cell differentiation  integral component of membrane  cAMP-mediated signaling  cAMP-mediated signaling  myelination in peripheral nervous system  myelination  laminin binding  extracellular matrix binding  heart trabecula formation  
NDEx NetworkADGRG6
Atlas of Cancer Signalling NetworkADGRG6
Wikipedia pathwaysADGRG6
Orthology - Evolution
OrthoDB57211
GeneTree (enSembl)ENSG00000112414
Phylogenetic Trees/Animal Genes : TreeFamADGRG6
HOVERGENQ86SQ4
HOGENOMQ86SQ4
Homologs : HomoloGeneADGRG6
Homology/Alignments : Family Browser (UCSC)ADGRG6
Gene fusions - Rearrangements
Tumor Fusion PortalADGRG6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADGRG6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADGRG6
dbVarADGRG6
ClinVarADGRG6
1000_GenomesADGRG6 
Exome Variant ServerADGRG6
ExAC (Exome Aggregation Consortium)ENSG00000112414
GNOMAD BrowserENSG00000112414
Genetic variants : HAPMAP57211
Genomic Variants (DGV)ADGRG6 [DGVbeta]
DECIPHERADGRG6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADGRG6 
Mutations
ICGC Data PortalADGRG6 
TCGA Data PortalADGRG6 
Broad Tumor PortalADGRG6
OASIS PortalADGRG6 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDADGRG6
BioMutasearch ADGRG6
DgiDB (Drug Gene Interaction Database)ADGRG6
DoCM (Curated mutations)ADGRG6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADGRG6 (select a term)
intoGenADGRG6
Cancer3DADGRG6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612243    616503   
Orphanet
DisGeNETADGRG6
MedgenADGRG6
Genetic Testing Registry ADGRG6
NextProtQ86SQ4 [Medical]
TSGene57211
GENETestsADGRG6
Target ValidationADGRG6
Huge Navigator ADGRG6 [HugePedia]
snp3D : Map Gene to Disease57211
BioCentury BCIQADGRG6
ClinGenADGRG6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57211
Chemical/Pharm GKB GenePA134878328
Clinical trialADGRG6
Miscellaneous
canSAR (ICR)ADGRG6 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADGRG6
EVEXADGRG6
GoPubMedADGRG6
iHOPADGRG6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Dec 27 18:23:51 CET 2017

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