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ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide)

Identity

Alias_namesADH1
Other alias
HGNC (Hugo) ADH1A
LocusID (NCBI) 124
Atlas_Id 53093
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 99276366 and ends at 99291028 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADH1A   249
Cards
Entrez_Gene (NCBI)ADH1A  124  alcohol dehydrogenase 1A (class I), alpha polypeptide
AliasesADH1
GeneCards (Weizmann)ADH1A
Ensembl hg19 (Hinxton)ENSG00000187758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187758 [Gene_View]  chr4:99276366-99291028 [Contig_View]  ADH1A [Vega]
ICGC DataPortalENSG00000187758
TCGA cBioPortalADH1A
AceView (NCBI)ADH1A
Genatlas (Paris)ADH1A
WikiGenes124
SOURCE (Princeton)ADH1A
Genetics Home Reference (NIH)ADH1A
Genomic and cartography
GoldenPath hg38 (UCSC)ADH1A  -     chr4:99276366-99291028 -  4q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADH1A  -     4q23   [Description]    (hg19-Feb_2009)
EnsemblADH1A - 4q23 [CytoView hg19]  ADH1A - 4q23 [CytoView hg38]
Mapping of homologs : NCBIADH1A [Mapview hg19]  ADH1A [Mapview hg38]
OMIM103700   
Gene and transcription
Genbank (Entrez)AK290558 AK309597 BC074738 BC117442 BC126306
RefSeq transcript (Entrez)NM_000667
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADH1A
Cluster EST : UnigeneHs.654433 [ NCBI ]
CGAP (NCI)Hs.654433
Alternative Splicing GalleryENSG00000187758
Gene ExpressionADH1A [ NCBI-GEO ]   ADH1A [ EBI - ARRAY_EXPRESS ]   ADH1A [ SEEK ]   ADH1A [ MEM ]
Gene Expression Viewer (FireBrowse)ADH1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124
GTEX Portal (Tissue expression)ADH1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07327   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07327  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07327
Splice isoforms : SwissVarP07327
Catalytic activity : Enzyme1.1.1.1 [ Enzyme-Expasy ]   1.1.1.11.1.1.1 [ IntEnz-EBI ]   1.1.1.1 [ BRENDA ]   1.1.1.1 [ KEGG ]   
PhosPhoSitePlusP07327
Domaine pattern : Prosite (Expaxy)ADH_ZINC (PS00059)   
Domains : Interpro (EBI)ADH_C    ADH_N    ADH_Zn_CS    GroES-like    NAD(P)-bd_dom    PKS_ER   
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
Domain families : Smart (EMBL)PKS_ER (SM00829)  
Conserved Domain (NCBI)ADH1A
DMDM Disease mutations124
Blocks (Seattle)ADH1A
PDB (SRS)1HSO    1U3T   
PDB (PDBSum)1HSO    1U3T   
PDB (IMB)1HSO    1U3T   
PDB (RSDB)1HSO    1U3T   
Structural Biology KnowledgeBase1HSO    1U3T   
SCOP (Structural Classification of Proteins)1HSO    1U3T   
CATH (Classification of proteins structures)1HSO    1U3T   
SuperfamilyP07327
Human Protein AtlasENSG00000187758
Peptide AtlasP07327
HPRD00063
IPIIPI00218896   
Protein Interaction databases
DIP (DOE-UCLA)P07327
IntAct (EBI)P07327
FunCoupENSG00000187758
BioGRIDADH1A
STRING (EMBL)ADH1A
ZODIACADH1A
Ontologies - Pathways
QuickGOP07327
Ontology : AmiGOalcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  alcohol dehydrogenase activity, zinc-dependent  retinol dehydrogenase activity  protein binding  nucleoplasm  cytosol  cytosol  plasma membrane  alcohol metabolic process  ethanol oxidation  zinc ion binding  drug metabolic process  
Ontology : EGO-EBIalcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  alcohol dehydrogenase activity, zinc-dependent  retinol dehydrogenase activity  protein binding  nucleoplasm  cytosol  cytosol  plasma membrane  alcohol metabolic process  ethanol oxidation  zinc ion binding  drug metabolic process  
Pathways : KEGG   
NDEx NetworkADH1A
Atlas of Cancer Signalling NetworkADH1A
Wikipedia pathwaysADH1A
Orthology - Evolution
OrthoDB124
GeneTree (enSembl)ENSG00000187758
Phylogenetic Trees/Animal Genes : TreeFamADH1A
HOVERGENP07327
HOGENOMP07327
Homologs : HomoloGeneADH1A
Homology/Alignments : Family Browser (UCSC)ADH1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADH1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADH1A
dbVarADH1A
ClinVarADH1A
1000_GenomesADH1A 
Exome Variant ServerADH1A
ExAC (Exome Aggregation Consortium)ADH1A (select the gene name)
Genetic variants : HAPMAP124
Genomic Variants (DGV)ADH1A [DGVbeta]
DECIPHERADH1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADH1A 
Mutations
ICGC Data PortalADH1A 
TCGA Data PortalADH1A 
Broad Tumor PortalADH1A
OASIS PortalADH1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADH1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADH1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADH1A
DgiDB (Drug Gene Interaction Database)ADH1A
DoCM (Curated mutations)ADH1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADH1A (select a term)
intoGenADH1A
Cancer3DADH1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103700   
Orphanet
MedgenADH1A
Genetic Testing Registry ADH1A
NextProtP07327 [Medical]
TSGene124
GENETestsADH1A
Target ValidationADH1A
Huge Navigator ADH1A [HugePedia]
snp3D : Map Gene to Disease124
BioCentury BCIQADH1A
ClinGenADH1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD124
Chemical/Pharm GKB GenePA24570
Clinical trialADH1A
Miscellaneous
canSAR (ICR)ADH1A (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADH1A
EVEXADH1A
GoPubMedADH1A
iHOPADH1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:56:23 CEST 2017

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