| Nomenclature |
|---|
| HGNC (Hugo) | ADH1B 250 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ADH1B 125 alcohol dehydrogenase 1B (class I), beta polypeptide |
| Aliases | ADH2; HEL-S-117 |
| GeneCards (Weizmann) | ADH1B |
| Ensembl hg19 (Hinxton) | ENSG00000196616 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000196616 [Gene_View] ENSG00000196616 [Sequence] chr4:99306387-99321442 [Contig_View] ADH1B [Vega] |
| ICGC DataPortal | ENSG00000196616 |
| TCGA cBioPortal | ADH1B |
| AceView (NCBI) | ADH1B |
| Genatlas (Paris) | ADH1B |
| WikiGenes | 125 |
| SOURCE (Princeton) | ADH1B |
| Genetics Home Reference (NIH) | ADH1B |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ADH1B - chr4:99306387-99321442 - 4q23 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ADH1B - 4q23 [Description] (hg19-Feb_2009) |
| Ensembl | ADH1B - 4q23 [CytoView hg19] ADH1B - 4q23 [CytoView hg38] |
| Mapping of homologs : NCBI | ADH1B [Mapview hg19] ADH1B [Mapview hg38] |
| OMIM | 103720 103780 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF153821 AI702614 AK299409 AK301018 AK303945 |
| RefSeq transcript (Entrez) | NM_000668 NM_001286650 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ADH1B |
| Cluster EST : Unigene | Hs.4 [ NCBI ] |
| CGAP (NCI) | Hs.4 |
| Alternative Splicing Gallery | ENSG00000196616 |
| Gene Expression | ADH1B [ NCBI-GEO ] ADH1B [ EBI - ARRAY_EXPRESS ]
ADH1B [ SEEK ] ADH1B [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ADH1B [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 125 |
| GTEX Portal (Tissue expression) | ADH1B |
| Human Protein Atlas | ENSG00000196616-ADH1B [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P00325 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P00325 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P00325 |
| Splice isoforms : SwissVar | P00325 |
| Catalytic activity : Enzyme | 1.1.1.1 [ Enzyme-Expasy ] 1.1.1.11.1.1.1 [ IntEnz-EBI ] 1.1.1.1 [ BRENDA ] 1.1.1.1 [ KEGG ] |
| PhosPhoSitePlus | P00325 |
| Domaine pattern : Prosite (Expaxy) | ADH_ZINC (PS00059) |
| Domains : Interpro (EBI) | ADH_C ADH_N ADH_Zn_CS GroES-like_sf NAD(P)-bd_dom_sf PKS_ER |
| Domain families : Pfam (Sanger) | ADH_N (PF08240) ADH_zinc_N (PF00107) |
| Domain families : Pfam (NCBI) | pfam08240 pfam00107 |
| Domain families : Smart (EMBL) | PKS_ER (SM00829) |
| Conserved Domain (NCBI) | ADH1B |
| DMDM Disease mutations | 125 |
| Blocks (Seattle) | ADH1B |
| PDB (RSDB) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| PDB Europe | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| PDB (PDBSum) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| PDB (IMB) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| Structural Biology KnowledgeBase | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| SCOP (Structural Classification of Proteins) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| CATH (Classification of proteins structures) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
| Superfamily | P00325 |
| Human Protein Atlas [tissue] | ENSG00000196616-ADH1B [tissue] |
| Peptide Atlas | P00325 |
| HPRD | 00065 |
| IPI | IPI00473031 IPI00872991 IPI01018979 IPI00965164 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P00325 |
| IntAct (EBI) | P00325 |
| FunCoup | ENSG00000196616 |
| BioGRID | ADH1B |
| STRING (EMBL) | ADH1B |
| ZODIAC | ADH1B |
| Ontologies - Pathways |
|---|
| QuickGO | P00325 |
| Ontology : AmiGO | alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent retinol dehydrogenase activity nucleoplasm cytosol cytosol cytosol plasma membrane ethanol oxidation ethanol oxidation ethanol oxidation zinc ion binding zinc ion binding retinol metabolic process retinoic acid metabolic process |
| Ontology : EGO-EBI | alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent retinol dehydrogenase activity nucleoplasm cytosol cytosol cytosol plasma membrane ethanol oxidation ethanol oxidation ethanol oxidation zinc ion binding zinc ion binding retinol metabolic process retinoic acid metabolic process |
| Pathways : KEGG | Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Chemical carcinogenesis |
| NDEx Network | ADH1B |
| Atlas of Cancer Signalling Network | ADH1B |
| Wikipedia pathways | ADH1B |
| Orthology - Evolution |
|---|
| OrthoDB | 125 |
| GeneTree (enSembl) | ENSG00000196616 |
| Phylogenetic Trees/Animal Genes : TreeFam | ADH1B |
| HOGENOM | P00325 |
| Homologs : HomoloGene | ADH1B |
| Homology/Alignments : Family Browser (UCSC) | ADH1B |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ADH1B |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ADH1B [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ADH1B |
| dbVar | ADH1B |
| ClinVar | ADH1B |
| 1000_Genomes | ADH1B |
| Exome Variant Server | ADH1B |
| ExAC (Exome Aggregation Consortium) | ENSG00000196616 |
| GNOMAD Browser | ENSG00000196616 |
| Varsome Browser | ADH1B |
| Genetic variants : HAPMAP | 125 |
| Genomic Variants (DGV) | ADH1B [DGVbeta] |
| DECIPHER | ADH1B [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ADH1B |
| Mutations |
|---|
| ICGC Data Portal | ADH1B |
| TCGA Data Portal | ADH1B |
| Broad Tumor Portal | ADH1B |
| OASIS Portal | ADH1B [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ADH1B [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | ADH1B |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search ADH1B |
| DgiDB (Drug Gene Interaction Database) | ADH1B |
| DoCM (Curated mutations) | ADH1B (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ADH1B (select a term) |
| intoGen | ADH1B |
| Cancer3D | ADH1B(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 103720 103780 |
| Orphanet | |
| DisGeNET | ADH1B |
| Medgen | ADH1B |
| Genetic Testing Registry | ADH1B
|
| NextProt | P00325 [Medical] |
| TSGene | 125 |
| GENETests | ADH1B |
| Target Validation | ADH1B |
| Huge Navigator |
ADH1B [HugePedia] |
| snp3D : Map Gene to Disease | 125 |
| BioCentury BCIQ | ADH1B |
| ClinGen | ADH1B |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 125 |
| Chemical/Pharm GKB Gene | PA24571 |
| Clinical trial | ADH1B |
| Miscellaneous |
|---|
| canSAR (ICR) | ADH1B (select the gene name) |
| DataMed Index | ADH1B |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 367 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ADH1B |
| EVEX | ADH1B |
| GoPubMed | ADH1B |
| iHOP | ADH1B |
