| Nomenclature |
HGNC (Hugo) | ADH1B 250 |
| Cards |
Entrez_Gene (NCBI) | ADH1B 125 alcohol dehydrogenase 1B (class I), beta polypeptide |
Aliases | ADH2; HEL-S-117 |
GeneCards (Weizmann) | ADH1B |
Ensembl hg19 (Hinxton) | ENSG00000196616 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000196616 [Gene_View]  ENSG00000196616 [Sequence] chr4:99306387-99321442 [Contig_View] ADH1B [Vega] |
ICGC DataPortal | ENSG00000196616 |
TCGA cBioPortal | ADH1B |
AceView (NCBI) | ADH1B |
Genatlas (Paris) | ADH1B |
WikiGenes | 125 |
SOURCE (Princeton) | ADH1B |
Genetics Home Reference (NIH) | ADH1B |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | ADH1B - chr4:99306387-99321442 - 4q23 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | ADH1B - 4q23 [Description] (hg19-Feb_2009) |
Ensembl | ADH1B - 4q23 [CytoView hg19] ADH1B - 4q23 [CytoView hg38] |
Mapping of homologs : NCBI | ADH1B [Mapview hg19] ADH1B [Mapview hg38] |
OMIM | 103720 103780 |
| Gene and transcription |
Genbank (Entrez) | AF153821 AI702614 AK299409 AK301018 AK303945 |
RefSeq transcript (Entrez) | NM_000668 NM_001286650 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | ADH1B |
Cluster EST : Unigene | Hs.4 [ NCBI ] |
CGAP (NCI) | Hs.4 |
Alternative Splicing Gallery | ENSG00000196616 |
Gene Expression | ADH1B [ NCBI-GEO ] ADH1B [ EBI - ARRAY_EXPRESS ]
ADH1B [ SEEK ] ADH1B [ MEM ] |
Gene Expression Viewer (FireBrowse) | ADH1B [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 125 |
GTEX Portal (Tissue expression) | ADH1B |
Human Protein Atlas | ENSG00000196616-ADH1B [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | P00325 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | P00325 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | P00325 |
Splice isoforms : SwissVar | P00325 |
Catalytic activity : Enzyme | 1.1.1.1 [ Enzyme-Expasy ] 1.1.1.11.1.1.1 [ IntEnz-EBI ] 1.1.1.1 [ BRENDA ] 1.1.1.1 [ KEGG ] |
PhosPhoSitePlus | P00325 |
Domaine pattern : Prosite (Expaxy) | ADH_ZINC (PS00059) |
Domains : Interpro (EBI) | ADH_C ADH_N ADH_Zn_CS GroES-like_sf NAD(P)-bd_dom_sf PKS_ER |
Domain families : Pfam (Sanger) | ADH_N (PF08240) ADH_zinc_N (PF00107) |
Domain families : Pfam (NCBI) | pfam08240 pfam00107 |
Domain families : Smart (EMBL) | PKS_ER (SM00829) |
Conserved Domain (NCBI) | ADH1B |
DMDM Disease mutations | 125 |
Blocks (Seattle) | ADH1B |
PDB (RSDB) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
PDB Europe | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
PDB (PDBSum) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
PDB (IMB) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
Structural Biology KnowledgeBase | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
SCOP (Structural Classification of Proteins) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
CATH (Classification of proteins structures) | 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD |
Superfamily | P00325 |
Human Protein Atlas [tissue] | ENSG00000196616-ADH1B [tissue] |
Peptide Atlas | P00325 |
HPRD | 00065 |
IPI | IPI00473031 IPI00872991 IPI01018979 IPI00965164 |
| Protein Interaction databases |
DIP (DOE-UCLA) | P00325 |
IntAct (EBI) | P00325 |
FunCoup | ENSG00000196616 |
BioGRID | ADH1B |
STRING (EMBL) | ADH1B |
ZODIAC | ADH1B |
| Ontologies - Pathways |
QuickGO | P00325 |
Ontology : AmiGO | alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent retinol dehydrogenase activity nucleoplasm cytosol cytosol cytosol plasma membrane ethanol oxidation ethanol oxidation ethanol oxidation zinc ion binding zinc ion binding retinol metabolic process retinoic acid metabolic process |
Ontology : EGO-EBI | alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent alcohol dehydrogenase activity, zinc-dependent retinol dehydrogenase activity nucleoplasm cytosol cytosol cytosol plasma membrane ethanol oxidation ethanol oxidation ethanol oxidation zinc ion binding zinc ion binding retinol metabolic process retinoic acid metabolic process |
Pathways : KEGG | Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Chemical carcinogenesis |
NDEx Network | ADH1B |
Atlas of Cancer Signalling Network | ADH1B |
Wikipedia pathways | ADH1B |
| Orthology - Evolution |
OrthoDB | 125 |
GeneTree (enSembl) | ENSG00000196616 |
Phylogenetic Trees/Animal Genes : TreeFam | ADH1B |
HOGENOM | P00325 |
Homologs : HomoloGene | ADH1B |
Homology/Alignments : Family Browser (UCSC) | ADH1B |
| Gene fusions - Rearrangements |
Fusion : Quiver | ADH1B |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | ADH1B [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | ADH1B |
dbVar | ADH1B |
ClinVar | ADH1B |
1000_Genomes | ADH1B |
Exome Variant Server | ADH1B |
ExAC (Exome Aggregation Consortium) | ENSG00000196616 |
GNOMAD Browser | ENSG00000196616 |
Varsome Browser | ADH1B |
Genetic variants : HAPMAP | 125 |
Genomic Variants (DGV) | ADH1B [DGVbeta] |
DECIPHER | ADH1B [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | ADH1B |
| Mutations |
ICGC Data Portal | ADH1B |
TCGA Data Portal | ADH1B |
Broad Tumor Portal | ADH1B |
OASIS Portal | ADH1B [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | ADH1B [overview] [genome browser] [tissue] [distribution] |
Mutations and Diseases : HGMD | ADH1B |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search ADH1B |
DgiDB (Drug Gene Interaction Database) | ADH1B |
DoCM (Curated mutations) | ADH1B (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | ADH1B (select a term) |
intoGen | ADH1B |
Cancer3D | ADH1B(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 103720 103780 |
Orphanet | |
DisGeNET | ADH1B |
Medgen | ADH1B |
Genetic Testing Registry | ADH1B
|
NextProt | P00325 [Medical] |
TSGene | 125 |
GENETests | ADH1B |
Target Validation | ADH1B |
Huge Navigator |
ADH1B [HugePedia] |
snp3D : Map Gene to Disease | 125 |
BioCentury BCIQ | ADH1B |
ClinGen | ADH1B |
| Clinical trials, drugs, therapy |
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Chemical/Protein Interactions : CTD | 125 |
Chemical/Pharm GKB Gene | PA24571 |
Clinical trial | ADH1B |
| Miscellaneous |
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canSAR (ICR) | ADH1B (select the gene name) |
DataMed Index | ADH1B |
| Probes |
---|
| Litterature |
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PubMed | 367 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | ADH1B |
EVEX | ADH1B |
GoPubMed | ADH1B |
iHOP | ADH1B |