Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 126
MIM: 103730
HGNC: 251
Ensembl: ENSG00000248144
Variants:
dbSNP: 126
ClinVar: 126
TCGA: ENSG00000248144
COSMIC: ADH1C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000248144 | ENST00000510055 | A0A087WU81 |
| ENSG00000248144 | ENST00000511397 | A0A087WUC4 |
| ENSG00000248144 | ENST00000515683 | P00326 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166156476 | rs698 | Variant | VipGene | associated | 16792560, 14693654 | ||
| PA443309 | Alcoholism | Disease | ClinicalAnnotation, VipGene | associated | PD | 17285601, 17134660, 32451486 | |
| PA445204 | Ovarian Neoplasms | Disease | ClinicalAnnotation | associated | PD | 24533712 | |
| PA448004 | abacavir | Chemical | Pathway | associated | 24625462 | ||
| PA448073 | ethanol | Chemical | ClinicalAnnotation, VipGene | associated | PD | 14693654, 32451486 | |
| PA449014 | cisplatin | Chemical | ClinicalAnnotation | associated | PD | 24533712 | |
| PA449165 | cyclophosphamide | Chemical | ClinicalAnnotation | associated | PD | 24533712 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37890508 | 2024 | LncRNA LINC01339 Hinders the Development of Wilms' Tumor via MiR-135b-3p/ADH1C Axis. | 0 |
| 37890508 | 2024 | LncRNA LINC01339 Hinders the Development of Wilms' Tumor via MiR-135b-3p/ADH1C Axis. | 0 |
| 37378938 | 2023 | Association of ADH1B rs1229984, ADH1C rs698, and ALDH2 rs671 with Alcohol abuse and Alcoholic Cirrhosis in People Living in Northeast Vietnam. | 1 |
| 37510297 | 2023 | ADH1B, ADH1B/C and CYP2E1 Gene Polymorphism and the Risk of Fetal Alcohol Spectrum Disorder. | 1 |
| 37378938 | 2023 | Association of ADH1B rs1229984, ADH1C rs698, and ALDH2 rs671 with Alcohol abuse and Alcoholic Cirrhosis in People Living in Northeast Vietnam. | 1 |
| 37510297 | 2023 | ADH1B, ADH1B/C and CYP2E1 Gene Polymorphism and the Risk of Fetal Alcohol Spectrum Disorder. | 1 |
| 35612423 | 2022 | ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells. | 4 |
| 36580007 | 2022 | Single Nucleotide Polymorphisms of ADH1B, ADH1C and ALDH2 Genes in 235 People Living in Thai Nguyen Province of Vietnam. | 2 |
| 36701787 | 2022 | INVESTIGATION OF ALCOHOL DEHYDROGENASE (ADH3) GENE POLYMOPHISM IN PATIENTS WITH CHRONIC ALCOHOLIC PANCRATITIS IN AZERBAIJAN POPULATION. | 0 |
| 35612423 | 2022 | ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells. | 4 |
| 36580007 | 2022 | Single Nucleotide Polymorphisms of ADH1B, ADH1C and ALDH2 Genes in 235 People Living in Thai Nguyen Province of Vietnam. | 2 |
| 36701787 | 2022 | INVESTIGATION OF ALCOHOL DEHYDROGENASE (ADH3) GENE POLYMOPHISM IN PATIENTS WITH CHRONIC ALCOHOLIC PANCRATITIS IN AZERBAIJAN POPULATION. | 0 |
| 34293286 | 2021 | The role of alcohol dehydrogenase 1C in regulating inflammatory responses in ulcerative colitis. | 6 |
| 34293286 | 2021 | The role of alcohol dehydrogenase 1C in regulating inflammatory responses in ulcerative colitis. | 6 |
| 32107439 | 2020 | Association of alcohol dehydrogenase and aldehyde dehydrogenase Polymorphism with Spontaneous Deep Intracerebral Haemorrhage in the Taiwan population. | 6 |
Citation
Dessen P
ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53084/adh1c
