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ADH6 (alcohol dehydrogenase 6 (class V))

Identity

Alias_symbol (synonym)ADH-5
Other alias
HGNC (Hugo) ADH6
LocusID (NCBI) 130
Atlas_Id 46776
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 99204722 and ends at 99219246 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TET2 (4q24) / ADH6 (4q23)TET2 4q24 / ADH6 4q23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADH6   255
Cards
Entrez_Gene (NCBI)ADH6  130  alcohol dehydrogenase 6 (class V)
AliasesADH-5
GeneCards (Weizmann)ADH6
Ensembl hg19 (Hinxton)ENSG00000172955 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172955 [Gene_View]  chr4:99204722-99219246 [Contig_View]  ADH6 [Vega]
ICGC DataPortalENSG00000172955
TCGA cBioPortalADH6
AceView (NCBI)ADH6
Genatlas (Paris)ADH6
WikiGenes130
SOURCE (Princeton)ADH6
Genetics Home Reference (NIH)ADH6
Genomic and cartography
GoldenPath hg38 (UCSC)ADH6  -     chr4:99204722-99219246 -  4q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADH6  -     4q23   [Description]    (hg19-Feb_2009)
EnsemblADH6 - 4q23 [CytoView hg19]  ADH6 - 4q23 [CytoView hg38]
Mapping of homologs : NCBIADH6 [Mapview hg19]  ADH6 [Mapview hg38]
OMIM103735   
Gene and transcription
Genbank (Entrez)AJ278908 AK092768 AK298290 AK316326 BC039065
RefSeq transcript (Entrez)NM_000672 NM_001102470
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADH6
Cluster EST : UnigeneHs.586161 [ NCBI ]
CGAP (NCI)Hs.586161
Alternative Splicing GalleryENSG00000172955
Gene ExpressionADH6 [ NCBI-GEO ]   ADH6 [ EBI - ARRAY_EXPRESS ]   ADH6 [ SEEK ]   ADH6 [ MEM ]
Gene Expression Viewer (FireBrowse)ADH6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130
GTEX Portal (Tissue expression)ADH6
Human Protein AtlasENSG00000172955-ADH6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28332   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28332  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28332
Splice isoforms : SwissVarP28332
PhosPhoSitePlusP28332
Domaine pattern : Prosite (Expaxy)ADH_ZINC (PS00059)   
Domains : Interpro (EBI)ADH_C    ADH_N    ADH_Zn_CS    GroES-like    NAD(P)-bd_dom    PKS_ER   
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
Domain families : Smart (EMBL)PKS_ER (SM00829)  
Conserved Domain (NCBI)ADH6
DMDM Disease mutations130
Blocks (Seattle)ADH6
SuperfamilyP28332
Human Protein Atlas [tissue]ENSG00000172955-ADH6 [tissue]
Peptide AtlasP28332
HPRD00067
IPIIPI00292698   IPI00939339   IPI00791428   IPI00965480   IPI00216792   IPI00965781   IPI00966014   
Protein Interaction databases
DIP (DOE-UCLA)P28332
IntAct (EBI)P28332
FunCoupENSG00000172955
BioGRIDADH6
STRING (EMBL)ADH6
ZODIACADH6
Ontologies - Pathways
QuickGOP28332
Ontology : AmiGOalcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  cytosol  ethanol oxidation  ethanol oxidation  zinc ion binding  response to ethanol  extracellular exosome  
Ontology : EGO-EBIalcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  cytosol  ethanol oxidation  ethanol oxidation  zinc ion binding  response to ethanol  extracellular exosome  
Pathways : KEGG   
NDEx NetworkADH6
Atlas of Cancer Signalling NetworkADH6
Wikipedia pathwaysADH6
Orthology - Evolution
OrthoDB130
GeneTree (enSembl)ENSG00000172955
Phylogenetic Trees/Animal Genes : TreeFamADH6
HOVERGENP28332
HOGENOMP28332
Homologs : HomoloGeneADH6
Homology/Alignments : Family Browser (UCSC)ADH6
Gene fusions - Rearrangements
Fusion: TCGA_MDACCTET2 4q24 ADH6 4q23 LGG
Tumor Fusion PortalADH6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADH6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADH6
dbVarADH6
ClinVarADH6
1000_GenomesADH6 
Exome Variant ServerADH6
ExAC (Exome Aggregation Consortium)ENSG00000172955
GNOMAD BrowserENSG00000172955
Genetic variants : HAPMAP130
Genomic Variants (DGV)ADH6 [DGVbeta]
DECIPHERADH6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADH6 
Mutations
ICGC Data PortalADH6 
TCGA Data PortalADH6 
Broad Tumor PortalADH6
OASIS PortalADH6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADH6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADH6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADH6
DgiDB (Drug Gene Interaction Database)ADH6
DoCM (Curated mutations)ADH6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADH6 (select a term)
intoGenADH6
Cancer3DADH6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103735   
Orphanet
DisGeNETADH6
MedgenADH6
Genetic Testing Registry ADH6
NextProtP28332 [Medical]
TSGene130
GENETestsADH6
Target ValidationADH6
Huge Navigator ADH6 [HugePedia]
snp3D : Map Gene to Disease130
BioCentury BCIQADH6
ClinGenADH6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130
Chemical/Pharm GKB GenePA24576
Clinical trialADH6
Miscellaneous
canSAR (ICR)ADH6 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADH6
EVEXADH6
GoPubMedADH6
iHOPADH6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:02:16 CET 2017

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