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ADI1 (acireductone dioxygenase 1)

Identity

Alias_symbol (synonym)SIPL
MTCBP-1
ARD
APL1
FLJ10913
HMFT1638
mtnD
Other aliasFe-ARD
MTCBP1
Ni-ARD
HGNC (Hugo) ADI1
LocusID (NCBI) 55256
Atlas_Id 45729
Location 2p25.3  [Link to chromosome band 2p25]
Location_base_pair Starts at 3497919 and ends at 3517747 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADI1 (2p25.3) / ADI1 (2p25.3)ADI1 (2p25.3) / KHDRBS3 (8q24.23)ADI1 (2p25.3) / RP13-512J5.1 ()
ADI1 (2p25.3) / TRIM14 (9q22.33)ADI1 (2p25.3) / TUBB6 (18p11.21)ADI1 (2p25.3) / ZFP91 (11q12.1)
KHDRBS3 (8q24.23) / ADI1 (2p25.3)ZNF626 (19p12) / ADI1 (2p25.3)ADI1 2p25.3 / KHDRBS3 8q24.23
ADI1 2p25.3 RP13-512J5.1ADI1 2p25.3 / ZFP91 11q12.1KHDRBS3 8q24.23 / ADI1 2p25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADI1   30576
Cards
Entrez_Gene (NCBI)ADI1  55256  acireductone dioxygenase 1
AliasesAPL1; ARD; Fe-ARD; HMFT1638; 
MTCBP1; Ni-ARD; SIPL; mtnD
GeneCards (Weizmann)ADI1
Ensembl hg19 (Hinxton)ENSG00000182551 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182551 [Gene_View]  chr2:3497919-3517747 [Contig_View]  ADI1 [Vega]
ICGC DataPortalENSG00000182551
TCGA cBioPortalADI1
AceView (NCBI)ADI1
Genatlas (Paris)ADI1
WikiGenes55256
SOURCE (Princeton)ADI1
Genetics Home Reference (NIH)ADI1
Genomic and cartography
GoldenPath hg38 (UCSC)ADI1  -     chr2:3497919-3517747 -  2p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADI1  -     2p25.3   [Description]    (hg19-Feb_2009)
EnsemblADI1 - 2p25.3 [CytoView hg19]  ADI1 - 2p25.3 [CytoView hg38]
Mapping of homologs : NCBIADI1 [Mapview hg19]  ADI1 [Mapview hg38]
OMIM613400   
Gene and transcription
Genbank (Entrez)AB073609 AB158319 AF087863 AF403478 AK001775
RefSeq transcript (Entrez)NM_001306077 NM_018269
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_187522
Consensus coding sequences : CCDS (NCBI)ADI1
Cluster EST : UnigeneHs.502773 [ NCBI ]
CGAP (NCI)Hs.502773
Alternative Splicing GalleryENSG00000182551
Gene ExpressionADI1 [ NCBI-GEO ]   ADI1 [ EBI - ARRAY_EXPRESS ]   ADI1 [ SEEK ]   ADI1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55256
GTEX Portal (Tissue expression)ADI1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BV57   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BV57  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BV57
Splice isoforms : SwissVarQ9BV57
PhosPhoSitePlusQ9BV57
Domains : Interpro (EBI)ARD    ARD_euk    RmlC-like_jellyroll    RmlC_Cupin   
Domain families : Pfam (Sanger)ARD (PF03079)   
Domain families : Pfam (NCBI)pfam03079   
Conserved Domain (NCBI)ADI1
DMDM Disease mutations55256
Blocks (Seattle)ADI1
PDB (SRS)4QGN   
PDB (PDBSum)4QGN   
PDB (IMB)4QGN   
PDB (RSDB)4QGN   
Structural Biology KnowledgeBase4QGN   
SCOP (Structural Classification of Proteins)4QGN   
CATH (Classification of proteins structures)4QGN   
SuperfamilyQ9BV57
Human Protein AtlasENSG00000182551
Peptide AtlasQ9BV57
HPRD17607
IPIIPI00651738   IPI00470791   IPI00893165   
Protein Interaction databases
DIP (DOE-UCLA)Q9BV57
IntAct (EBI)Q9BV57
FunCoupENSG00000182551
BioGRIDADI1
STRING (EMBL)ADI1
ZODIACADI1
Ontologies - Pathways
QuickGOQ9BV57
Ontology : AmiGOprotein binding  nucleus  cytoplasm  cytosol  plasma membrane  acireductone dioxygenase [iron(II)-requiring] activity  oxidoreductase activity  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  metal ion binding  oxidation-reduction process  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  cytosol  plasma membrane  acireductone dioxygenase [iron(II)-requiring] activity  oxidoreductase activity  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  metal ion binding  oxidation-reduction process  
Pathways : KEGGCysteine and methionine metabolism   
NDEx NetworkADI1
Atlas of Cancer Signalling NetworkADI1
Wikipedia pathwaysADI1
Orthology - Evolution
OrthoDB55256
GeneTree (enSembl)ENSG00000182551
Phylogenetic Trees/Animal Genes : TreeFamADI1
HOVERGENQ9BV57
HOGENOMQ9BV57
Homologs : HomoloGeneADI1
Homology/Alignments : Family Browser (UCSC)ADI1
Gene fusions - Rearrangements
Fusion : MitelmanADI1/KHDRBS3 [2p25.3/8q24.23]  
Fusion : MitelmanADI1/ZFP91 [2p25.3/11q12.1]  [t(2;11)(p25;q12)]  
Fusion : MitelmanKHDRBS3/ADI1 [8q24.23/2p25.3]  [t(2;8)(p25;q24)]  
Fusion: TCGAADI1 2p25.3 KHDRBS3 8q24.23 BRCA
Fusion: TCGAADI1 2p25.3 RP13-512J5.1 LUAD
Fusion: TCGAADI1 2p25.3 ZFP91 11q12.1 PRAD
Fusion: TCGAKHDRBS3 8q24.23 ADI1 2p25.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADI1
dbVarADI1
ClinVarADI1
1000_GenomesADI1 
Exome Variant ServerADI1
ExAC (Exome Aggregation Consortium)ADI1 (select the gene name)
Genetic variants : HAPMAP55256
Genomic Variants (DGV)ADI1 [DGVbeta]
DECIPHERADI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADI1 
Mutations
ICGC Data PortalADI1 
TCGA Data PortalADI1 
Broad Tumor PortalADI1
OASIS PortalADI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADI1
DgiDB (Drug Gene Interaction Database)ADI1
DoCM (Curated mutations)ADI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADI1 (select a term)
intoGenADI1
Cancer3DADI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613400   
Orphanet
MedgenADI1
Genetic Testing Registry ADI1
NextProtQ9BV57 [Medical]
TSGene55256
GENETestsADI1
Huge Navigator ADI1 [HugePedia]
snp3D : Map Gene to Disease55256
BioCentury BCIQADI1
ClinGenADI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55256
Chemical/Pharm GKB GenePA143485291
Clinical trialADI1
Miscellaneous
canSAR (ICR)ADI1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADI1
EVEXADI1
GoPubMedADI1
iHOPADI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:05:13 CEST 2017

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