Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ADIPOQ (adiponectin, C1Q and collagen domain containing)

Identity

Alias_namesACDC
adipocyte
Alias_symbol (synonym)ACRP30
AdipoQ
apM1
GBP28
adiponectin
Other aliasADIPQTL1
ADPN
APM-1
APM1
HGNC (Hugo) ADIPOQ
LocusID (NCBI) 9370
Atlas_Id 46188
Location 3q27.3  [Link to chromosome band 3q27]
Location_base_pair Starts at 186842674 and ends at 186858463 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADIPOQ (3q27.3) / PCNT (21q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADIPOQ   13633
Cards
Entrez_Gene (NCBI)ADIPOQ  9370  adiponectin, C1Q and collagen domain containing
AliasesACDC; ACRP30; ADIPQTL1; ADPN; 
APM-1; APM1; GBP28
GeneCards (Weizmann)ADIPOQ
Ensembl hg19 (Hinxton)ENSG00000181092 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181092 [Gene_View]  ENSG00000181092 [Sequence]  chr3:186842674-186858463 [Contig_View]  ADIPOQ [Vega]
ICGC DataPortalENSG00000181092
TCGA cBioPortalADIPOQ
AceView (NCBI)ADIPOQ
Genatlas (Paris)ADIPOQ
WikiGenes9370
SOURCE (Princeton)ADIPOQ
Genetics Home Reference (NIH)ADIPOQ
Genomic and cartography
GoldenPath hg38 (UCSC)ADIPOQ  -     chr3:186842674-186858463 +  3q27.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADIPOQ  -     3q27.3   [Description]    (hg19-Feb_2009)
ADIPOQ - 3q27.3 [CytoView hg19]  ADIPOQ - 3q27.3 [CytoView hg38]
Mapping of homologs : NCBIADIPOQ [Mapview hg19]  ADIPOQ [Mapview hg38]
OMIM605441   612556   
Gene and transcription
Genbank (Entrez)AK291525 AK312868 AL832470 AX767959 BC054496
RefSeq transcript (Entrez)NM_001177800 NM_004797
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADIPOQ
Cluster EST : UnigeneHs.80485 [ NCBI ]
CGAP (NCI)Hs.80485
Alternative Splicing GalleryENSG00000181092
Gene ExpressionADIPOQ [ NCBI-GEO ]   ADIPOQ [ EBI - ARRAY_EXPRESS ]   ADIPOQ [ SEEK ]   ADIPOQ [ MEM ]
Gene Expression Viewer (FireBrowse)ADIPOQ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9370
GTEX Portal (Tissue expression)ADIPOQ
Human Protein AtlasENSG00000181092-ADIPOQ [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15848   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15848  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15848
Splice isoforms : SwissVarQ15848
PhosPhoSitePlusQ15848
Domaine pattern : Prosite (Expaxy)C1Q (PS50871)   
Domains : Interpro (EBI)C1q_dom    Collagen    Tumour_necrosis_fac-like_dom   
Domain families : Pfam (Sanger)C1q (PF00386)    Collagen (PF01391)   
Domain families : Pfam (NCBI)pfam00386    pfam01391   
Domain families : Smart (EMBL)C1Q (SM00110)  
Conserved Domain (NCBI)ADIPOQ
DMDM Disease mutations9370
Blocks (Seattle)ADIPOQ
PDB (RSDB)4DOU   
PDB Europe4DOU   
PDB (PDBSum)4DOU   
PDB (IMB)4DOU   
Structural Biology KnowledgeBase4DOU   
SCOP (Structural Classification of Proteins)4DOU   
CATH (Classification of proteins structures)4DOU   
SuperfamilyQ15848
Human Protein Atlas [tissue]ENSG00000181092-ADIPOQ [tissue]
Peptide AtlasQ15848
HPRD05671
IPIIPI00020019   
Protein Interaction databases
DIP (DOE-UCLA)Q15848
IntAct (EBI)Q15848
FunCoupENSG00000181092
BioGRIDADIPOQ
STRING (EMBL)ADIPOQ
ZODIACADIPOQ
Ontologies - Pathways
QuickGOQ15848
Ontology : AmiGOresponse to hypoxia  positive regulation of protein phosphorylation  signaling receptor binding  cytokine activity  hormone activity  extracellular matrix structural constituent  protein binding  extracellular region  extracellular region  collagen trimer  extracellular space  endoplasmic reticulum  glucose metabolic process  generation of precursor metabolites and energy  fatty acid beta-oxidation  response to nutrient  circadian rhythm  response to bacterium  response to sucrose  response to glucose  positive regulation of signal transduction  cell surface  regulation of signaling receptor activity  negative regulation of platelet-derived growth factor receptor signaling pathway  positive regulation of protein kinase A signaling  negative regulation of macrophage derived foam cell differentiation  negative regulation of tumor necrosis factor-mediated signaling pathway  positive regulation of cholesterol efflux  regulation of glucose metabolic process  response to activity  fatty acid oxidation  negative regulation of cell migration  negative regulation of granulocyte differentiation  negative regulation of protein autophosphorylation  positive regulation of cellular protein metabolic process  negative regulation of tumor necrosis factor production  positive regulation of interleukin-8 production  cellular response to insulin stimulus  positive regulation of myeloid cell apoptotic process  sialic acid binding  negative regulation of heterotypic cell-cell adhesion  low-density lipoprotein particle clearance  response to tumor necrosis factor  cellular response to drug  regulation of fatty acid biosynthetic process  glucose homeostasis  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of MAP kinase activity  response to ethanol  negative regulation of fat cell differentiation  negative regulation of macrophage differentiation  negative regulation of low-density lipoprotein particle receptor biosynthetic process  negative regulation of gluconeogenesis  negative regulation of blood pressure  negative regulation of transcription, DNA-templated  positive regulation of fatty acid metabolic process  positive regulation of glucose import  negative regulation of hormone secretion  negative regulation of inflammatory response  negative regulation of inflammatory response  positive regulation of peptidyl-tyrosine phosphorylation  negative regulation of phagocytosis  negative regulation of synaptic transmission  brown fat cell differentiation  protein homooligomerization  response to glucocorticoid  collagen-containing extracellular matrix  protein heterotrimerization  negative regulation of ERK1 and ERK2 cascade  response to linoleic acid  detection of oxidative stress  cellular response to cAMP  positive regulation of monocyte chemotactic protein-1 production  cellular response to epinephrine stimulus  protein localization to plasma membrane  negative regulation of intracellular protein transport  positive regulation of cold-induced thermogenesis  negative regulation of cold-induced thermogenesis  negative regulation of receptor binding  negative regulation of vascular smooth muscle cell proliferation  negative regulation of vascular associated smooth muscle cell migration  negative regulation of DNA biosynthetic process  positive regulation of glycogen (starch) synthase activity  positive regulation of metanephric glomerular visceral epithelial cell development  positive regulation of cAMP-dependent protein kinase activity  positive regulation of renal albumin absorption  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway  negative regulation of metanephric mesenchymal cell migration  
Ontology : EGO-EBIresponse to hypoxia  positive regulation of protein phosphorylation  signaling receptor binding  cytokine activity  hormone activity  extracellular matrix structural constituent  protein binding  extracellular region  extracellular region  collagen trimer  extracellular space  endoplasmic reticulum  glucose metabolic process  generation of precursor metabolites and energy  fatty acid beta-oxidation  response to nutrient  circadian rhythm  response to bacterium  response to sucrose  response to glucose  positive regulation of signal transduction  cell surface  regulation of signaling receptor activity  negative regulation of platelet-derived growth factor receptor signaling pathway  positive regulation of protein kinase A signaling  negative regulation of macrophage derived foam cell differentiation  negative regulation of tumor necrosis factor-mediated signaling pathway  positive regulation of cholesterol efflux  regulation of glucose metabolic process  response to activity  fatty acid oxidation  negative regulation of cell migration  negative regulation of granulocyte differentiation  negative regulation of protein autophosphorylation  positive regulation of cellular protein metabolic process  negative regulation of tumor necrosis factor production  positive regulation of interleukin-8 production  cellular response to insulin stimulus  positive regulation of myeloid cell apoptotic process  sialic acid binding  negative regulation of heterotypic cell-cell adhesion  low-density lipoprotein particle clearance  response to tumor necrosis factor  cellular response to drug  regulation of fatty acid biosynthetic process  glucose homeostasis  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of MAP kinase activity  response to ethanol  negative regulation of fat cell differentiation  negative regulation of macrophage differentiation  negative regulation of low-density lipoprotein particle receptor biosynthetic process  negative regulation of gluconeogenesis  negative regulation of blood pressure  negative regulation of transcription, DNA-templated  positive regulation of fatty acid metabolic process  positive regulation of glucose import  negative regulation of hormone secretion  negative regulation of inflammatory response  negative regulation of inflammatory response  positive regulation of peptidyl-tyrosine phosphorylation  negative regulation of phagocytosis  negative regulation of synaptic transmission  brown fat cell differentiation  protein homooligomerization  response to glucocorticoid  collagen-containing extracellular matrix  protein heterotrimerization  negative regulation of ERK1 and ERK2 cascade  response to linoleic acid  detection of oxidative stress  cellular response to cAMP  positive regulation of monocyte chemotactic protein-1 production  cellular response to epinephrine stimulus  protein localization to plasma membrane  negative regulation of intracellular protein transport  positive regulation of cold-induced thermogenesis  negative regulation of cold-induced thermogenesis  negative regulation of receptor binding  negative regulation of vascular smooth muscle cell proliferation  negative regulation of vascular associated smooth muscle cell migration  negative regulation of DNA biosynthetic process  positive regulation of glycogen (starch) synthase activity  positive regulation of metanephric glomerular visceral epithelial cell development  positive regulation of cAMP-dependent protein kinase activity  positive regulation of renal albumin absorption  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway  negative regulation of metanephric mesenchymal cell migration  
Pathways : KEGGPPAR signaling pathway    Adipocytokine signaling pathway    Type II diabetes mellitus    Non-alcoholic fatty liver disease (NAFLD)   
NDEx NetworkADIPOQ
Atlas of Cancer Signalling NetworkADIPOQ
Wikipedia pathwaysADIPOQ
Orthology - Evolution
OrthoDB9370
GeneTree (enSembl)ENSG00000181092
Phylogenetic Trees/Animal Genes : TreeFamADIPOQ
HOGENOMQ15848
Homologs : HomoloGeneADIPOQ
Homology/Alignments : Family Browser (UCSC)ADIPOQ
Gene fusions - Rearrangements
Fusion : QuiverADIPOQ
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADIPOQ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADIPOQ
dbVarADIPOQ
ClinVarADIPOQ
1000_GenomesADIPOQ 
Exome Variant ServerADIPOQ
ExAC (Exome Aggregation Consortium)ENSG00000181092
GNOMAD BrowserENSG00000181092
Varsome BrowserADIPOQ
Genetic variants : HAPMAP9370
Genomic Variants (DGV)ADIPOQ [DGVbeta]
DECIPHERADIPOQ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADIPOQ 
Mutations
ICGC Data PortalADIPOQ 
TCGA Data PortalADIPOQ 
Broad Tumor PortalADIPOQ
OASIS PortalADIPOQ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADIPOQ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADIPOQ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADIPOQ
DgiDB (Drug Gene Interaction Database)ADIPOQ
DoCM (Curated mutations)ADIPOQ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADIPOQ (select a term)
intoGenADIPOQ
Cancer3DADIPOQ(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605441    612556   
Orphanet
DisGeNETADIPOQ
MedgenADIPOQ
Genetic Testing Registry ADIPOQ
NextProtQ15848 [Medical]
TSGene9370
GENETestsADIPOQ
Target ValidationADIPOQ
Huge Navigator ADIPOQ [HugePedia]
snp3D : Map Gene to Disease9370
BioCentury BCIQADIPOQ
ClinGenADIPOQ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9370
Chemical/Pharm GKB GenePA134933118
Clinical trialADIPOQ
Miscellaneous
canSAR (ICR)ADIPOQ (select the gene name)
DataMed IndexADIPOQ
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADIPOQ
EVEXADIPOQ
GoPubMedADIPOQ
iHOPADIPOQ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 21 15:35:11 CET 2019
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