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ADIPOR2 (adiponectin receptor 2)

Identity

Alias (NCBI)ACDCR2
PAQR2
HGNC (Hugo) ADIPOR2
HGNC Alias symbPAQR2
ACDCR2
LocusID (NCBI) 79602
Atlas_Id 46466
Location 12p13.33  [Link to chromosome band 12p13]
Location_base_pair Starts at 1691070 and ends at 1788673 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADIPOR2 (12p13.33) / ANKRD42 (11q14.1)ADIPOR2 (12p13.33) / BOLA2 (16p11.2)ADIPOR2 (12p13.33) / DCP1B (12p13.33)
ADIPOR2 (12p13.33) / ERC1 (12p13.33)ADIPOR2 (12p13.33) / FOXJ2 (12p13.31)ADIPOR2 (12p13.33) / NINJ2 (12p13.33)
ADIPOR2 (12p13.33) / WNT5B (12p13.33)ITPR2 (12p12.1) / ADIPOR2 (12p13.33)LOC100124692 () / ADIPOR2 (12p13.33)
ADIPOR2 12p13.33 / DCP1B 12p13.33ADIPOR2 12p13.33 / ERC1 12p13.33ADIPOR2 12p13.33 / FOXJ2 12p13.31
ADIPOR2 12p13.33 / NINJ2 12p13.33ADIPOR2 12p13.33 / WNT5B 12p13.33ITPR2 12p12.1 / ADIPOR2 12p13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ADIPOR2   24041
Cards
Entrez_Gene (NCBI)ADIPOR2    adiponectin receptor 2
AliasesACDCR2; PAQR2
GeneCards (Weizmann)ADIPOR2
Ensembl hg19 (Hinxton)ENSG00000006831 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000006831 [Gene_View]  ENSG00000006831 [Sequence]  chr12:1691070-1788673 [Contig_View]  ADIPOR2 [Vega]
ICGC DataPortalENSG00000006831
TCGA cBioPortalADIPOR2
AceView (NCBI)ADIPOR2
Genatlas (Paris)ADIPOR2
SOURCE (Princeton)ADIPOR2
Genetics Home Reference (NIH)ADIPOR2
Genomic and cartography
GoldenPath hg38 (UCSC)ADIPOR2  -     chr12:1691070-1788673 +  12p13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADIPOR2  -     12p13.33   [Description]    (hg19-Feb_2009)
GoldenPathADIPOR2 - 12p13.33 [CytoView hg19]  ADIPOR2 - 12p13.33 [CytoView hg38]
ImmunoBaseENSG00000006831
Genome Data Viewer NCBIADIPOR2 [Mapview hg19]  
OMIM607946   
Gene and transcription
Genbank (Entrez)AK025085 AK127196 AK128511 AY424280 BC004906
RefSeq transcript (Entrez)NM_001375363 NM_001375364 NM_001375365 NM_024551
Consensus coding sequences : CCDS (NCBI)ADIPOR2
Gene ExpressionADIPOR2 [ NCBI-GEO ]   ADIPOR2 [ EBI - ARRAY_EXPRESS ]   ADIPOR2 [ SEEK ]   ADIPOR2 [ MEM ]
Gene Expression Viewer (FireBrowse)ADIPOR2 [ Firebrowse - Broad ]
GenevisibleExpression of ADIPOR2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79602
GTEX Portal (Tissue expression)ADIPOR2
Human Protein AtlasENSG00000006831-ADIPOR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86V24   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86V24  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86V24
PhosPhoSitePlusQ86V24
Domains : Interpro (EBI)AdipoR/HlyIII-related   
Domain families : Pfam (Sanger)HlyIII (PF03006)   
Domain families : Pfam (NCBI)pfam03006   
Conserved Domain (NCBI)ADIPOR2
PDB (RSDB)5LWY    5LX9    5LXA    6KS1   
PDB Europe5LWY    5LX9    5LXA    6KS1   
PDB (PDBSum)5LWY    5LX9    5LXA    6KS1   
PDB (IMB)5LWY    5LX9    5LXA    6KS1   
Structural Biology KnowledgeBase5LWY    5LX9    5LXA    6KS1   
SCOP (Structural Classification of Proteins)5LWY    5LX9    5LXA    6KS1   
CATH (Classification of proteins structures)5LWY    5LX9    5LXA    6KS1   
SuperfamilyQ86V24
AlphaFold pdb e-kbQ86V24   
Human Protein Atlas [tissue]ENSG00000006831-ADIPOR2 [tissue]
HPRD06403
Protein Interaction databases
DIP (DOE-UCLA)Q86V24
IntAct (EBI)Q86V24
BioGRIDADIPOR2
STRING (EMBL)ADIPOR2
ZODIACADIPOR2
Ontologies - Pathways
QuickGOQ86V24
Ontology : AmiGOpositive regulation of protein phosphorylation  protein binding  plasma membrane  plasma membrane  heart development  female pregnancy  response to nutrient  response to fructose  hormone-mediated signaling pathway  negative regulation of gene expression  response to amine  integral component of membrane  fatty acid oxidation  negative regulation of cell growth  intrinsic component of plasma membrane  response to lipopolysaccharide  adiponectin-activated signaling pathway  adiponectin-activated signaling pathway  signaling receptor activity  regulation of fatty acid biosynthetic process  response to drug  glucose homeostasis  response to ethanol  positive regulation of glucose import  metal ion binding  adiponectin binding  vascular wound healing  negative regulation of hepatic stellate cell migration  cellular response to fatty acid  adipokinetic hormone receptor activity  positive regulation of cold-induced thermogenesis  
Ontology : EGO-EBIpositive regulation of protein phosphorylation  protein binding  plasma membrane  plasma membrane  heart development  female pregnancy  response to nutrient  response to fructose  hormone-mediated signaling pathway  negative regulation of gene expression  response to amine  integral component of membrane  fatty acid oxidation  negative regulation of cell growth  intrinsic component of plasma membrane  response to lipopolysaccharide  adiponectin-activated signaling pathway  adiponectin-activated signaling pathway  signaling receptor activity  regulation of fatty acid biosynthetic process  response to drug  glucose homeostasis  response to ethanol  positive regulation of glucose import  metal ion binding  adiponectin binding  vascular wound healing  negative regulation of hepatic stellate cell migration  cellular response to fatty acid  adipokinetic hormone receptor activity  positive regulation of cold-induced thermogenesis  
Pathways : KEGGAdipocytokine signaling pathway    Non-alcoholic fatty liver disease (NAFLD)   
NDEx NetworkADIPOR2
Atlas of Cancer Signalling NetworkADIPOR2
Wikipedia pathwaysADIPOR2
Orthology - Evolution
OrthoDB79602
GeneTree (enSembl)ENSG00000006831
Phylogenetic Trees/Animal Genes : TreeFamADIPOR2
Homologs : HomoloGeneADIPOR2
Homology/Alignments : Family Browser (UCSC)ADIPOR2
Gene fusions - Rearrangements
Fusion : MitelmanADIPOR2/DCP1B [12p13.33/12p13.33]  
Fusion : MitelmanADIPOR2/ERC1 [12p13.33/12p13.33]  
Fusion : MitelmanADIPOR2/FOXJ2 [12p13.33/12p13.31]  
Fusion : MitelmanADIPOR2/NINJ2 [12p13.33/12p13.33]  
Fusion : MitelmanADIPOR2/WNT5B [12p13.33/12p13.33]  
Fusion : MitelmanITPR2/ADIPOR2 [12p12.1/12p13.33]  
Fusion : QuiverADIPOR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADIPOR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADIPOR2
dbVarADIPOR2
ClinVarADIPOR2
MonarchADIPOR2
1000_GenomesADIPOR2 
Exome Variant ServerADIPOR2
GNOMAD BrowserENSG00000006831
Varsome BrowserADIPOR2
ACMGADIPOR2 variants
VarityQ86V24
Genomic Variants (DGV)ADIPOR2 [DGVbeta]
DECIPHERADIPOR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADIPOR2 
Mutations
ICGC Data PortalADIPOR2 
TCGA Data PortalADIPOR2 
Broad Tumor PortalADIPOR2
OASIS PortalADIPOR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADIPOR2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DADIPOR2
Mutations and Diseases : HGMDADIPOR2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaADIPOR2
DgiDB (Drug Gene Interaction Database)ADIPOR2
DoCM (Curated mutations)ADIPOR2
CIViC (Clinical Interpretations of Variants in Cancer)ADIPOR2
Cancer3DADIPOR2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607946   
Orphanet
DisGeNETADIPOR2
MedgenADIPOR2
Genetic Testing Registry ADIPOR2
NextProtQ86V24 [Medical]
GENETestsADIPOR2
Target ValidationADIPOR2
Huge Navigator ADIPOR2 [HugePedia]
ClinGenADIPOR2
Clinical trials, drugs, therapy
MyCancerGenomeADIPOR2
Protein Interactions : CTDADIPOR2
Pharm GKB GenePA128394711
PharosQ86V24
Clinical trialADIPOR2
Miscellaneous
canSAR (ICR)ADIPOR2
HarmonizomeADIPOR2
DataMed IndexADIPOR2
Probes
Litterature
PubMed154 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXADIPOR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:58:40 CEST 2021

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