ADIPOR2 (adiponectin receptor 2)

2007-02-01  

Identity

HGNC
LOCATION
12p13.33
LOCUSID
ALIAS
ACDCR2,PAQR2
FUSION GENES

Other Information

Locus ID:

NCBI: 79602
MIM: 607946
HGNC: 24041
Ensembl: ENSG00000006831

Variants:

dbSNP: 79602
ClinVar: 79602
TCGA: ENSG00000006831
COSMIC: ADIPOR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006831ENST00000357103Q86V24

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Adipocytokine signaling pathwayKEGGko04920
Adipocytokine signaling pathwayKEGGhsa04920
Non-alcoholic fatty liver disease (NAFLD)KEGGhsa04932
Non-alcoholic fatty liver disease (NAFLD)KEGGko04932
AMPK signaling pathwayKEGGhsa04152
AMPK signaling pathwayKEGGko04152
MetabolismREACTOMER-HSA-1430728
Integration of energy metabolismREACTOMER-HSA-163685
AMPK inhibits chREBP transcriptional activation activityREACTOMER-HSA-163680
Longevity regulating pathwayKEGGhsa04211

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
128023372003Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.639
154540912004Adiponectin and its receptors are expressed in bone-forming cells.108
206826872010Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.88
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
166781252006Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cells.83
233556302013Molecular pathways: adiponectin and leptin signaling in cancer.68
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
162058832005Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.51
146519882003Expression of adiponectin receptors in pancreatic beta cells.47
151059892004Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes.42

Citation

Dessen P

ADIPOR2 (adiponectin receptor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46466/adipor2