ADO (2-aminoethanethiol dioxygenase)

2014-11-01  

Identity

HGNC
LOCATION
10q21.3
LOCUSID
ALIAS
C10orf22
FUSION GENES

Other Information

Locus ID:

NCBI: 84890
MIM: 611392
HGNC: 23506
Ensembl: ENSG00000181915

Variants:

dbSNP: 84890
ClinVar: 84890
TCGA: ENSG00000181915
COSMIC: ADO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181915ENST00000373783Q96SZ5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Taurine and hypotaurine metabolismKEGGko00430
Taurine and hypotaurine metabolismKEGGhsa00430
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Sulfur amino acid metabolismREACTOMER-HSA-1614635
Degradation of cysteine and homocysteineREACTOMER-HSA-1614558

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA444552HypertensionDiseaseClinicalAnnotationassociatedPD31327267
PA449899hydrochlorothiazideChemicalClinicalAnnotationassociatedPD31327267

References

Pubmed IDYearTitleCitations
175818192007Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase.31
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
312731182019Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants.10

Citation

Dessen P

ADO (2-aminoethanethiol dioxygenase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60167/ado