ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent)

2014-11-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
C17orf48,MDS006,NBLA03831
FUSION GENES

Other Information

Locus ID:

NCBI: 56985
HGNC: 30925
Ensembl: ENSG00000170222

Variants:

dbSNP: 56985
ClinVar: 56985
TCGA: ENSG00000170222
COSMIC: ADPRM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170222ENST00000379774Q3LIE5
ENSG00000170222ENST00000379774W0NWJ0
ENSG00000170222ENST00000468843Q3LIE5
ENSG00000170222ENST00000609540V9GYR6

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Glycerophospholipid metabolismKEGGko00564
Purine metabolismKEGGhsa00230
Glycerophospholipid metabolismKEGGhsa00564
MetabolismREACTOMER-HSA-1430728
Metabolism of nucleotidesREACTOMER-HSA-15869
Phosphate bond hydrolysis by NUDT proteinsREACTOMER-HSA-2393930

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
256924882015Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase.1

Citation

Dessen P

ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60172/adprm