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ADRA1D (adrenoceptor alpha 1D)

Identity

Alias_namesadrenergic
Alias_symbol (synonym)ADRA1R
ADRA1A
ADRA1
Other aliasALPHA1
DAR
dJ779E11.2
HGNC (Hugo) ADRA1D
LocusID (NCBI) 146
Atlas_Id 55369
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 4201278 and ends at 4229659 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADRA1D (20p13) / ADRA1D (20p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADRA1D   280
Cards
Entrez_Gene (NCBI)ADRA1D  146  adrenoceptor alpha 1D
AliasesADRA1; ADRA1A; ADRA1R; ALPHA1; 
DAR; dJ779E11.2
GeneCards (Weizmann)ADRA1D
Ensembl hg19 (Hinxton)ENSG00000171873 [Gene_View]  chr20:4201278-4229659 [Contig_View]  ADRA1D [Vega]
Ensembl hg38 (Hinxton)ENSG00000171873 [Gene_View]  chr20:4201278-4229659 [Contig_View]  ADRA1D [Vega]
ICGC DataPortalENSG00000171873
TCGA cBioPortalADRA1D
AceView (NCBI)ADRA1D
Genatlas (Paris)ADRA1D
WikiGenes146
SOURCE (Princeton)ADRA1D
Genetics Home Reference (NIH)ADRA1D
Genomic and cartography
GoldenPath hg19 (UCSC)ADRA1D  -     chr20:4201278-4229659 -  20p13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ADRA1D  -     20p13   [Description]    (hg38-Dec_2013)
EnsemblADRA1D - 20p13 [CytoView hg19]  ADRA1D - 20p13 [CytoView hg38]
Mapping of homologs : NCBIADRA1D [Mapview hg19]  ADRA1D [Mapview hg38]
OMIM104219   
Gene and transcription
Genbank (Entrez)L31772 S70782 U03864
RefSeq transcript (Entrez)NM_000678
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)ADRA1D
Cluster EST : UnigeneHs.557 [ NCBI ]
CGAP (NCI)Hs.557
Alternative Splicing GalleryENSG00000171873
Gene ExpressionADRA1D [ NCBI-GEO ]   ADRA1D [ EBI - ARRAY_EXPRESS ]   ADRA1D [ SEEK ]   ADRA1D [ MEM ]
Gene Expression Viewer (FireBrowse)ADRA1D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)146
GTEX Portal (Tissue expression)ADRA1D
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25100   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25100  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25100
Splice isoforms : SwissVarP25100
PhosPhoSitePlusP25100
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)ADR_fam    ADRA1D_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)ADRA1D
DMDM Disease mutations146
Blocks (Seattle)ADRA1D
SuperfamilyP25100
Human Protein AtlasENSG00000171873
Peptide AtlasP25100
HPRD00079
IPIIPI00012725   
Protein Interaction databases
DIP (DOE-UCLA)P25100
IntAct (EBI)P25100
FunCoupENSG00000171873
BioGRIDADRA1D
STRING (EMBL)ADRA1D
ZODIACADRA1D
Ontologies - Pathways
QuickGOP25100
Ontology : AmiGOnorepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure  alpha1-adrenergic receptor activity  protein binding  plasma membrane  integral component of plasma membrane  DNA metabolic process  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  cell-cell signaling  multicellular organism development  cell proliferation  positive regulation of cell proliferation  positive regulation of vasoconstriction  positive regulation of smooth muscle contraction  adenylate cyclase-activating adrenergic receptor signaling pathway  
Ontology : EGO-EBInorepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure  alpha1-adrenergic receptor activity  protein binding  plasma membrane  integral component of plasma membrane  DNA metabolic process  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  cell-cell signaling  multicellular organism development  cell proliferation  positive regulation of cell proliferation  positive regulation of vasoconstriction  positive regulation of smooth muscle contraction  adenylate cyclase-activating adrenergic receptor signaling pathway  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Adrenergic signaling in cardiomyocytes    Vascular smooth muscle contraction    Salivary secretion   
NDEx NetworkADRA1D
Atlas of Cancer Signalling NetworkADRA1D
Wikipedia pathwaysADRA1D
Orthology - Evolution
OrthoDB146
GeneTree (enSembl)ENSG00000171873
Phylogenetic Trees/Animal Genes : TreeFamADRA1D
HOVERGENP25100
HOGENOMP25100
Homologs : HomoloGeneADRA1D
Homology/Alignments : Family Browser (UCSC)ADRA1D
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADRA1D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADRA1D
dbVarADRA1D
ClinVarADRA1D
1000_GenomesADRA1D 
Exome Variant ServerADRA1D
ExAC (Exome Aggregation Consortium)ADRA1D (select the gene name)
Genetic variants : HAPMAP146
Genomic Variants (DGV)ADRA1D [DGVbeta]
DECIPHER (Syndromes)20:4201278-4229659  ENSG00000171873
CONAN: Copy Number AnalysisADRA1D 
Mutations
ICGC Data PortalADRA1D 
TCGA Data PortalADRA1D 
Broad Tumor PortalADRA1D
OASIS PortalADRA1D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADRA1D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADRA1D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADRA1D
DgiDB (Drug Gene Interaction Database)ADRA1D
DoCM (Curated mutations)ADRA1D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADRA1D (select a term)
intoGenADRA1D
Cancer3DADRA1D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104219   
Orphanet
MedgenADRA1D
Genetic Testing Registry ADRA1D
NextProtP25100 [Medical]
TSGene146
GENETestsADRA1D
Huge Navigator ADRA1D [HugePedia]
snp3D : Map Gene to Disease146
BioCentury BCIQADRA1D
ClinGenADRA1D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD146
Chemical/Pharm GKB GenePA24597
Clinical trialADRA1D
Miscellaneous
canSAR (ICR)ADRA1D (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADRA1D
EVEXADRA1D
GoPubMedADRA1D
iHOPADRA1D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:46:52 CEST 2017

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