ADRM1 (ADRM1 26S proteasome ubiquitin receptor)

2003-06-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
ARM-1,ARM1,GP110,PSMD16
FUSION GENES

Other Information

Locus ID:

NCBI: 11047
MIM: 610650
HGNC: 15759
Ensembl: ENSG00000130706

Variants:

dbSNP: 11047
ClinVar: 11047
TCGA: ENSG00000130706
COSMIC: ADRM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130706ENST00000253003Q16186
ENSG00000130706ENST00000462554A0A087WUX6
ENSG00000130706ENST00000491935Q16186
ENSG00000130706ENST00000620230A0A087WX59

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
ProteasomeKEGGko03050
ProteasomeKEGGhsa03050
Proteasome, 19S regulatory particle (PA700)KEGGhsa_M00341
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
Proteasome, 19S regulatory particle (PA700)KEGGM00341
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DeubiquitinationREACTOMER-HSA-5688426
UCH proteinasesREACTOMER-HSA-5689603
Ub-specific processing proteasesREACTOMER-HSA-5689880

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381510172024hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.3
388903912024The high expression of ADRM1 in hepatocellular carcinoma is closely related to tumor immune infiltration and is regulated by miR-891a-5p.0
381510172024hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.3
388903912024The high expression of ADRM1 in hepatocellular carcinoma is closely related to tumor immune infiltration and is regulated by miR-891a-5p.0
372684712023Potential of adhesion-regulating molecule 1 (ADRM1) as a biomarker for patients with renal clear-cell carcinoma or papillary-cell carcinoma.0
375183562023LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models.0
372684712023Potential of adhesion-regulating molecule 1 (ADRM1) as a biomarker for patients with renal clear-cell carcinoma or papillary-cell carcinoma.0
375183562023LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models.0
324242942021Proteomic analysis identifies mechanism(s) of overcoming bortezomib resistance via targeting ubiquitin receptor Rpn13.12
329160392021ADRM1 as a therapeutic target in hepatocellular carcinoma.5
334415352021Identification of novel anti-tumor therapeutic target via proteomic characterization of ubiquitin receptor ADRM1/Rpn13.9
349164942021Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.11
324242942021Proteomic analysis identifies mechanism(s) of overcoming bortezomib resistance via targeting ubiquitin receptor Rpn13.12
329160392021ADRM1 as a therapeutic target in hepatocellular carcinoma.5
334415352021Identification of novel anti-tumor therapeutic target via proteomic characterization of ubiquitin receptor ADRM1/Rpn13.9

Citation

Dessen P

ADRM1 (ADRM1 26S proteasome ubiquitin receptor)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/591/adrm1